Gestational diabetes mellitus (GDM), one of the complications associated with pregnancy is a big, characterized as a temporary form of diabetes caused by insulin resistance along with low / absent-adaptation pancreatic beta cells compensate for insulin demand increases, causing acute, long a term, and transgenerational health complications. The purpose of this study was to assess whether changes in gene expression of microRNAs associated with diabetes disease / cardiovascular / cerebrovascular present throughout the peripheral blood of children aged 3-11 years dropped from GDM complicated pregnancy.
A microRNA expression profiles to be substantially modified is found in children dropped from GDM pregnancies complicated. Almost all of microRNAs with the exception of miR-92A-3p, miR-155-5p, and miR-210-3p regulated. The microRNA expression profiles also differ between children after normal and GDM pregnancies complicated in relation to the presence of overweight / obesity, prehypertension / hypertension and / or heart valve problems and defects.
Always, screening by a combination of superior use microRNAs microRNAs individual, because the false positive rate of 10.0% was able to identify most children with aberrant expression of microRNA profiles (88.14% regardless of the clinical findings, 75.41% by clinically normal findings, and 96.49% with abnormal clinical findings). In addition, a higher incidence of heart valve problems and defects found in children with exposure before GDM.
Extensive file of the target prediction of all microRNAs aberrantly expressed in children dropped from GDM pregnancies complicated show that a large group of these genes are involved in ontology diabetes / cardiovascular / cerebrovascular disease. In general, children with exposure before GDM are at a higher risk of subsequent development of diabetes mellitus and cardiovascular / cerebrovascular disease, and would benefit from dispensarisation and implementation of primary prevention strategies.
MicroRNA expression profile in extracellular vesicles derived from ALV-J infected chicken semen
MicroRNA expression profiles in extracellular vesicles derived from ALV-J semen of infected chickens
MicroRNAs (miRNAs) have been reported to regulate the expression of genes in many processes. MiRNA in extracellular vesicles (EV) has also been studied, while no study miRNAs in EVS semen. Subgroup J Avian leukosis virus (ALV-J) can be transmitted v ertically, but the mechanism was not clear enough. This study was to examine the expression profile of miRNA in EVs semen and to investigate the relationship between it and the vertical transmission by gene ontology (GO) and pathway enrichment analysis.
Here, we first isolated and characterized EVS semen with Nanoparticle Tracking Analysis, Western Blot and transmission electron microscopy experiments. By sequencing in each EVS miRNA library, a typical 9 differentially expressed miRNA, including six up-regulated and 3 down-regulated, are identified . Target gene prediction, explanation GO and KEGG pathway enrichment analysis shows that the function may be associated with these miRNAs. Overall, these findings will improve our understanding of the content and composition of the miRNA in EVs semen and provide new insights into the critical role of regulation of miRNAs EVS semen in the transmission ALV-J.
EZ-10 Spin Column Viral DNA Miniprep Kit
VT81812
Bio Basic
50Preps
EUR 268.8
EZ-10 Spin Column Viral DNA Miniprep Kit
VT81813
Bio Basic
250preps
EUR 1011.6
EZ-10 Spin Column Fungal RNA Miniprep Kit
BS91915
Bio Basic
50Preps
EUR 128.51
EZ-10 Spin Column DNA Cleanup Miniprep Kit
BS367
Bio Basic
50Preps
EUR 91.97
EZ-10 Spin Column DNA Cleanup Miniprep Kit
BS368
Bio Basic
100preps
EUR 114.82
EZ-10 Spin Column Plasmid DNA Miniprep Kit
BS413
Bio Basic
50Preps
EUR 91.97
EZ-10 Spin Column Plasmid DNA Miniprep Kit
BS414
Bio Basic
100preps
EUR 114.82
EZ-10 Spin Column DNA Cleanup Miniprep Kit
BS668
Bio Basic
250preps
EUR 199.9
EZ-10 Spin Column Animal Total RNA Miniprep Kit
BS82312
Bio Basic
50Preps
EUR 116.64
EZ-10 Spin Column Animal Total RNA Miniprep Kit
BS82322
Bio Basic
250preps
EUR 298.55
EZ-10 Spin Column Yeast Plasmid DNA Miniprep Kit
BS467
Bio Basic
10Preps
EUR 78.28
EZ-10 Spin Column Yeast Plasmid DNA Miniprep Kit
BS468
Bio Basic
50Preps
EUR 133.08
EZ-10 Spin Column Yeast Plasmid DNA Miniprep Kit
BS469
Bio Basic
250preps
EUR 364.32
EZ-10 Spin Column Yeast Genomic DNA Miniprep Kit
BS8257
Bio Basic
50Preps
EUR 112.98
EZ-10 Spin Column Blood Genomic DNA Miniprep Kit
SK8253
Bio Basic
50Preps
EUR 100.08
EZ-10 Spin Column Blood Genomic DNA Miniprep Kit
SK8254
Bio Basic
100preps
EUR 144.86
EZ-10 Spin Column Plant Genomic DNA Miniprep Kit
SK8262
Bio Basic
100preps
EUR 144.86
EZ-10 Spin Column Animal Genomic DNA Miniprep Kit
BS427
Bio Basic
50Preps
EUR 98.36
EZ-10 Spin Column Animal Genomic DNA Miniprep Kit
BS628
Bio Basic
250preps
EUR 231.86
EZ-10 Spin Column Fungal Genomic DNA Miniprep Kit
FT82012
Bio Basic
50Preps
EUR 98.36
ApexPrep DNA Plasmid Miniprep Column Only
A5002-300
ApexBio
300 tests
EUR 296.4
ApexPrep DNA Plasmid Miniprep Column Only
A5002-50
ApexBio
50 tests
EUR 104.4
EZ-10 Spin Column Bacterial Genomic DNA Miniprep Kit
BS423
Bio Basic
50Preps
EUR 98.36
EZ-10 Spin Column Bacterial Genomic DNA Miniprep Kit
BS624
Bio Basic
250preps
EUR 231.86
EZ-10 Spin Column Total RNA Miniprep Super Kit
BS583
Bio Basic
20Preps
EUR 91.97
EZ-10 Spin Column Total RNA Miniprep Super Kit
BS584
Bio Basic
100preps
EUR 197.03
EZ-10 Spin Column Total RNA Miniprep Super Kit
BS784
Bio Basic
250preps
EUR 346.06
EZ-10 Spin Column Endotoxin-Free Plasmid DNA Miniprep Kit
BS71918
Bio Basic
50Preps
EUR 149.52
EZ-10 Spin Column Plasmid DNA Miniprep Kit, Low Copy Plasmid
BS4139
Bio Basic
50Preps
EUR 105.67
EZ-10 Spin Column Plasmid DNA Miniprep Kit, Low Copy Plasmid
BS4149
Bio Basic
100preps
EUR 136.74
Column-Pure Plasmid Mini-Prep Kit
D514
ABM
100 Preparations
EUR 105
Plasmid MiniPrep Kit
20-abx098081
Abbexa
Plasmid Miniprep Kit
K529-100
Biovision
each
EUR 352.8
Plasmid Miniprep Kit I
K1312-250
Biovision
each
EUR 444
Plasmid Miniprep Kit I
K1312-50
Biovision
each
EUR 339.6
Plasmid Miniprep Kit II
K1313-250
Biovision
each
EUR 444
Plasmid Miniprep Kit II
K1313-50
Biovision
each
EUR 339.6
Pure Plasmid Miniprep Kit
W0500-200
101Bio
-
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Pure Plasmid Miniprep Kit
W0500-50
101Bio
-
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PlantGene™ Miniprep Kit
10760052-1
Bio-WORLD
10 Prep(s)
EUR 43.56
PlantGene™ Miniprep Kit
10760052-2
Bio-WORLD
50 Prep(s)
EUR 133.34
PlantGene™ Miniprep Kit
10760052-3
Bio-WORLD
250 Prep(s)
EUR 453.32
Zenoquick RNA Miniprep Kit
Z5005-050
GenDepot
50 preps
EUR 343.2
Zenoquick RNA Miniprep Kit
Z5005-200
GenDepot
4x50 preps
EUR 1016.4
HiPure Plasmid MiniPrep Kit
20-abx098082
Abbexa
Plasmid Miniprep Kit (100 preps)
9K-006-0009
Bio Basic
100preps
EUR 246.88
Plasmid Miniprep Kit (200 preps)
9K-006-0010
Bio Basic
200preps, 200prep
EUR 328.31
EndoFree Plasmid Miniprep Kit
EP004
ELK Biotech
50T
EUR 151
ViraBind Adenovirus Miniprep Kit
VPK-099
Cell Biolabs
10 preps
EUR 734.4
Description: Purification of viruses via cesium chloride ultracentrifugation procedures can be tedious and time-consuming. ViraBind Adenovirus Purification Kits provide a much more efficient system for fast adenoviral purification with high yields. The ViraBind Adenovirus Miniprep Kit uses a special spin column to purify supernatant from a single T75 flask or 10cm dish per prep in about 30 minutes.
Pure Plasmid 96 Miniprep Kit
W0506-496
101Bio
-
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Whole Blood DNA MiniPrep Kit
EP008
ELK Biotech
50T
EUR 132
Zenoquick Plant RNA Miniprep Kit
Z5016-050
GenDepot
50 prep
EUR 343.2
ApexPrep DNA Plasmid Miniprep Kit
A5001-300
ApexBio
300 tests
EUR 338.4
ApexPrep DNA Plasmid Miniprep Kit
A5001-50
ApexBio
50 tests
EUR 115.2
EZ-10 DNAaway RNA Miniprep Kit
BS88133
Bio Basic
50Preps
EUR 155.92
EZ-10 DNAaway RNA Miniprep Kit
BS88136
Bio Basic
250preps
EUR 455.68
Endotoxin-Free Plasmid Miniprep Kit
W2106-50
101Bio
-
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LumiPure Plasmid spin miniprep Kit, 50
21583
Lumiprobe
50 preps
EUR 93.6
One-4-All Genomic DNA Miniprep Kit
BS88503
Bio Basic
50Preps
EUR 140.39
One-4-All Genomic DNA Miniprep Kit
BS88504
Bio Basic
100preps
EUR 204.7
One-4-All Genomic DNA Miniprep Kit
BS88505
Bio Basic
250preps
EUR 393.55
96-Well Plate Viral DNA Miniprep Kit
VT92032
Bio Basic
2XPlates, 192prep
EUR 495.86
Prolytic His-Tagged Protein Miniprep Kit
P6400-010
GenDepot
10 prep
EUR 303.6
Prolytic His-Tagged Protein Miniprep Kit
P6400-050
GenDepot
50 Prep
EUR 789.6
96-Well Plate DNA Cleanup Miniprep Kit
BS369
Bio Basic
5XPlates, 480prep
EUR 300.37
96-Well Plate DNA Cleanup Miniprep Kit
BS3692
Bio Basic
2xPlates, 192prep
EUR 186.19
96-Well Plate Plasmid DNA Miniprep Kit
BS415
Bio Basic
5XPlates, 480prep
EUR 300.37
96-Well Plate Plasmid DNA Miniprep Kit
BS4152
Bio Basic
2XPlates, 192prep
EUR 186.19
Zenoquick Plasmid Miniprep
Z1004-050
GenDepot
50 preps
EUR 183.6
Zenoquick Plasmid Miniprep
Z1004-200
GenDepot
200 preps
EUR 380.4
96 Well Plate Blood Genomic DNA Miniprep Kit
BT92031
Bio Basic
2Plates, 192prep
EUR 210.85
96 Well Plate Blood Genomic DNA Miniprep Kit
BT92032
Bio Basic
5Plates, 480prep
EUR 389.9
96 Well Plate Yeast Genomic DNA Miniprep Kit
BS8357
Bio Basic
2XPlates, 192prep
EUR 234.6
96-Well Plate Plant Genomic DNA Miniprep Kit
BS8361
Bio Basic
2XPlates, 192prep
EUR 234.6
96-Well Plate Animal Genomic DNA Miniprep Kit
BS437
Bio Basic
5XPlates, 480prep
EUR 435.58
96-Well Plate Animal Genomic DNA Miniprep Kit
BS4372
Bio Basic
2XPlates, 192prep
EUR 234.6
96-Well Plate Bacteria Genomic DNA Miniprep Kit
SK1292
Bio Basic
2XPlates, 192prep
EUR 210.85
96-Well Plate Bacteria Genomic DNA Miniprep Kit
SK1295
Bio Basic
5XPlates, 480prep
EUR 389.9
EZ-10 Total RNA Miniprep Kit (with Proteinase K)
BS88583
Bio Basic
50Preps
EUR 128.51
Zenoquick Yeast Plasmid Miniprep
Z1007-100
GenDepot
2x50 preps
EUR 278.4
Ultra-Fast 96-Well Plate Plasmid DNA Miniprep Kit
BS92028
Bio Basic
2XPlates, 192prep
EUR 254.7
Ultra-Fast 96-Well Plate Plasmid DNA Miniprep Kit
BS92029
Bio Basic
5XPlates, 480prep
EUR 437.4
Miniprep Kit For Plasmid DNA Extraction And Purification
MB1005-100Reactions
BosterBio
100 Reactions
EUR 171.6
Miniprep Kit For Plasmid DNA Extraction And Purification
MB1005-250Reactions
BosterBio
250 Reactions
EUR 310.8
Miniprep Kit For Plasmid DNA Extraction And Purification
MB1005-50Reactions
BosterBio
50 Reactions
EUR 144
All-In-One DNA/RNA Miniprep Kit (Cell, Tissue, Plant)
BS88203
Bio Basic
50Preps
EUR 146.78
All-In-One DNA/RNA/Protein Miniprep Kit (Cell, Tissue, Plant)
BS88003
Bio Basic
50Preps
EUR 155.92
96 Well Plate Bacterial Total RNA Miniprep Super Kit
BS585
Bio Basic
5XPlates, 480prep
EUR 585.38
96 Well Plate Bacterial Total RNA Miniprep Super Kit
BS5852
Bio Basic
2XPlates, 192prep
EUR 300.37
His-tag Protein Purification Mini Kit unit: 3-10mg/ column, 1 column
FYP101-5P
Yeastern Biotech
1 vial
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Micro desalting spin column set
MDC050
ProFoldin
50 columns
EUR 187.8
Description: This product includes 50 pre-packed spin-columns. Each column is to desalt 25 ul of sample. The volume of desalted sample is 25 to 30 ul.
Micro Phosphate Removal Column Set
MPR020
ProFoldin
20 columns
EUR 159.49
Description: This product includes 20 pre-packed spin-columns.
MicroRNA Isolation Kit
KS341025
Biochain
1 kit
EUR 247
Total RNA Plus Mini Kit (100 prep)-(gDNA removeal column)
FATRK-P_100
Favorgen
1 kit
EUR 110
Total RNA Plus Mini Kit (50 prep)-(gDNA removeal column)
FATRK-P_050
Favorgen
1 kit
EUR 62
Column Packing Kit
PACK-KIT
Next Advance
1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.
Plant MicroRNA Purification Kit
10760135-1
Bio-WORLD
25 Prep(s)
EUR 245.48
96-Well Plate Plasmid DNA Mini-Preps Kit (Vacuum Based)
B814152-0002
Bio Basic
2XPlates, 2XPlates
EUR 186.19
96-Well Plate Plasmid DNA Mini-Preps Kit (Vacuum Based)
B814152-0005
Bio Basic
5XPlates, 5XPlates
EUR 300.37
Human microrna-21(mir-21) ELISA Kit
SL3405Hu
Sunlong
96 Tests
EUR 468
microRNA-21-IN-1
T63879-10mg
TargetMol Chemicals
10mg
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Description: microRNA-21-IN-1
microRNA-21-IN-1
T63879-1mg
TargetMol Chemicals
1mg
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Description: microRNA-21-IN-1
microRNA-21-IN-1
T63879-50mg
TargetMol Chemicals
50mg
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Description: microRNA-21-IN-1
microRNA-21-IN-1
T63879-5mg
TargetMol Chemicals
5mg
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Description: microRNA-21-IN-1
microRNA-21-IN-2
T61093-10mg
TargetMol Chemicals
10mg
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Description: microRNA-21-IN-2
microRNA-21-IN-2
T61093-1mg
TargetMol Chemicals
1mg
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Description: microRNA-21-IN-2
microRNA-21-IN-2
T61093-50mg
TargetMol Chemicals
50mg
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Description: microRNA-21-IN-2
microRNA-21-IN-2
T61093-5mg
TargetMol Chemicals
5mg
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Description: microRNA-21-IN-2
rno-miRNome MicroRNA Profiling Kit [Rat]
RA680B-1
SBI
20 complete profiles
EUR 2006.4
hsa-miRNome MicroRNA Profiling Kit [Human]
RA660A-1
SBI
20 profiles
EUR 2212.8
mmu-miRNome MicroRNA Profiling Kit [Mouse]
RA670A-1
SBI
20 profiles
EUR 2046
EZ-10 Spin Column Plasmid DNA Min-preps Kit
BS614
Bio Basic
250preps
EUR 199.9
Preparative Membrane Protein Folding Column Set (column #1)
MFC01
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #1
Preparative Membrane Protein Folding Column Set (column #2)
MFC02
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #2
Preparative Membrane Protein Folding Column Set (column #3)
MFC03
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #3
Preparative Membrane Protein Folding Column Set (column #4)
MFC04
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #4
Preparative Membrane Protein Folding Column Set (column #5)
MFC05
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #5
Preparative Membrane Protein Folding Column Set (column #6)
MFC06
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #6
Preparative Membrane Protein Folding Column Set (column #7)
MFC07
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #7
Preparative Membrane Protein Folding Column Set (column #8)
MFC08
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #8
Preparative Membrane Protein Folding Column Set (column #9)
MFC09
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #9
Preparative Membrane Protein Folding Column Set (column #10)
MFC10
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent A, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #10
Preparative Membrane Protein Folding Column Set (column #11)
MFC11
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #11
Preparative Membrane Protein Folding Column Set (column #12)
MFC12
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #12
Preparative Membrane Protein Folding Column Set (column #13)
MFC13
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #13
Preparative Membrane Protein Folding Column Set (column #14)
MFC14
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #14
Preparative Membrane Protein Folding Column Set (column #15)
MFC15
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #15
Preparative Membrane Protein Folding Column Set (column #16)
MFC16
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #16
Preparative Membrane Protein Folding Column Set (column #17)
MFC17
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #17
Preparative Membrane Protein Folding Column Set (column #18)
MFC18
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #18
Preparative Membrane Protein Folding Column Set (column #19)
MFC19
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #19
Preparative Membrane Protein Folding Column Set (column #20)
MFC20
ProFoldin
kit
EUR 279.35
Description: This product includes 5ml of Reagent B, 8.4 ml of Reagent C, 15.4 ml of Solution S and 4 membrane protein folding columns #20
microRNAs (miRNAs) are small RNAs that regulate different biological processes. Our goal is to identify dysregulated miRNAs in the plasma and tissues of patients with abdominal aortic aneurysm (AAA) and exploring new potential targets involved in the AAA. Fifty-seven subjects were recruited for the study of plasma (30 patients with AAA, 16 healthy volunteers and 11 patients with atherosclerosis).