Proteomic and microRNA-omic profiles and potential mechanisms of dysfunction in pancreatic islet cells primed by inflammation

Diabetes is an inflammatory disease that induces the dysfunction of pancreatic islands. However, at best our knowledge, the potential underlying molecular mechanisms of this inflammatory process remain unknown. This study investigated microarna expression profiles (MIRNA / MIR) and protein through proteomics and mIRNA-OMICS. The lipopolysaccharide macrophage cellular medium (LRM) was used to stimulate the inflammation of Beta-TC-6 mouse island cells. Protein analysis revealed that 87 proteins were regulated and 42 proteins were regulated in the BETA-TC-6 cells treated with the LRR with respect to control cells.

In addition, MIRNA’s analysis revealed that 11 miRNas were regulated, while 28 miRNas were carried out in the Beta-TC-6 cells treated with the LRR with respect to control cells. The island cells exposed to inflammation have presented significant transcription protein levels of the MAFA transcription factor, pancreatic and duodenal homeobox 1, panel 6, HomeOBOX NKX-2.2 protein, protein associated with synaptosomale 25, glucagon and Insulin-2, while the expression of MIR-146A -5P and MIR-21A-5P have been regulated. It has also been determined that utility levels MIR-146A-5P and MIR-21A-5P can be mediated by NF-κB activation. The regulation of the decline of the Islet Factor Factor MRNA has been partially reversed by treating island cells with a MIR-21A-5P inhibitor. However, treatment with a mir-146a-5p inhibitor has not exercised the same effect.

Overall, the present study determined the molecular profiles of the cellular ignition of islets based on proteomics and mIRNA-OMICS, and indicated that proteins and mirnas with modified expressions can form a large network that serves as a role in The dysfunction of islets. In particular, the regulation of MIR-21A-5P in response to inflammation can contribute to the malfunction of the ist cells. However, how these mushas have settled the expression of some RNAs and proteins in the inflammation of ist cells requires further investigation.

The ancient microornas profiles of a sample of 14,300 years Canid confirm the taxonomic origin and give insights in the regulation of specific genes of the pleistocene tissues

The sequencing of the DNA is the current key technology of historical or old biological samples and has led to many exciting discoveries in the field of paleoganomics. However, functional information on tissue identity, cell composition or gene regulation can not be won from the DNA. Recent analyzes have shown that, under favorable conditions, RNA can also be sequenced by ancient samples, allowing studies at transcriptomic and regulatory level. Analysis of ancient RNA data from a Pleistocene Canid, we find hundreds of intact micro portions that are taxonomic informative, have a specificity of tissues and have functionally predictive characteristics. With an extraordinary age of 14,300 years, these microad sequences are by far the oldest ever reported.

The authenticity of the sequences is further supported by a) the presence of sequences specific to Canid / craniform which has never evolved outside this clade, b) patterns of expression specific to a fabric (cartilage, liver and muscle) that resemble those of modern dogs and c) RNA damage models that are clearly distinct from fresh samples. By performing enrichment analyzes of the IT micro-merchandemic target on ancient sequences, we predict the functions of the micro-lead compatible with their tissue expression model.

For example, we find a liver-specific Microrna that regulates metabolism of carbohydrates and famine responses in the canids. In summary, we show that simple micro-micro-microornaomicscriptomic analyzes can give functional insights in tissue identity, the cellular composition and the regulatory activity of the old samples and the biological processes that took place in the pleistocene, Thus holding a great promise for deeper ideas in the regulation of genes in animals off extinct animals. Based on the old sequencing of RNA.

 Proteomic and microRNA-omic profiles and potential mechanisms of dysfunction in pancreatic islet cells primed by inflammation
Proteomic and microRNA-omic profiles and potential mechanisms of dysfunction in pancreatic islet cells primed by inflammation

Exosomes derived from the human periodontal ligament cell promote bone regeneration by modifying microad profiles

The role and underlying mechanism of exosomes derived from human periodontal ligament stem cells (PDLSC) in osteogenesis are unclear. In this study, we identified PDLSC’s derived exosomes and found that osteogenic induction can improve the osteogenic capacity of PDLSC derived exosomes in promoting osteogenic differentiation of rat bone bone marrow stem cells (BMSCS). To study the underlying mechanism, we analyzed the exosomal expression profiles of Mirna of the infronted and osteogenic differentiated differentiated PDLSC by sequencing RNA. The results showed that seventy-two mirnas were regulated and thirty-five mirnas were regulated after osteogenic induction.

Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) Antibody

abx238835-100ug 100 ug
EUR 509

ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE101020-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE101020-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE101020-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Mouse Troponin C, slow skeletal and cardiac muscles, Tnnc1 ELISA

ELI-36461m 96 Tests
EUR 865

Bovine Troponin C, slow skeletal and cardiac muscles, TNNC1 ELIS

ELI-17222b 96 Tests
EUR 928

Porcine Troponin C, slow skeletal and cardiac muscles, TNNC1 ELI

ELI-39993p 96 Tests
EUR 928

Human Troponin C, slow skeletal and cardiac muscles, TNNC1 ELISA

ELI-40072h 96 Tests
EUR 824

Human TNNC1/ Troponin C, slow skeletal and cardiac muscles ELISA Kit

E2558Hu 1 Kit
EUR 605

Chicken Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555347-96tests 96 tests
EUR 911

Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555435-96tests 96 tests
EUR 786

Mouse Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555608-96tests 96 tests
EUR 739

Pig Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555672-96tests 96 tests
EUR 911

Cow Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555769-96tests 96 tests
EUR 911

Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx352187-96tests 96 tests
EUR 786

Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

20-abx153332
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Human Troponin C, slow skeletal and cardiac muscles

EK3670 96 tests
EUR 670
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Troponin C, slow skeletal and cardiac muscles in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE70102-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE70102-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE70102-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6)

KTE50026-48T 48T
EUR 425
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6)

KTE50026-5platesof96wells 5 plates of 96 wells
EUR 3026
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6)

KTE50026-96T 96T
EUR 756
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE30009-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE30009-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE30009-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Custom production of antibodies in 5 Rats using customer supplied antigen (std 63 days protocol)

RAT-5 1
EUR 1138

Rat Skeletal Muscle Tissue Lysate

LYSATE0010 200ug
EUR 150
Description: This cell lysate is prepared from rat skeletal muscle tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Total Protein Extraction Kit for Muscles (50 tests)

P5A06 - Ask for price

Rat Skeletal Muscle Whole tissue lysate

RAL-1467 1 mg
EUR 524

rno-miRNome MicroRNA Profiling Kit [Rat]

RA680B-1 20 complete profiles
EUR 1672

Myosin antibody (skeletal)

10R-7875 100 ug
EUR 322
Description: Mouse monoclonal Myosin antibody

Myosin antibody (skeletal)

10R-7876 100 ug
EUR 322
Description: Mouse monoclonal Myosin antibody

Skeletal Muscle Lysate

1407 0.1 mg
EUR 191
Description: Skeletal Muscle tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Skeletal Muscle Lysate

1467 0.1 mg
EUR 191
Description: Skeletal Muscle tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Skeletal Muscle Lysate

21-107 0.1 mg
EUR 285.5
Description: Bovine skeletal muscle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The bovine skeletal muscle tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the skeletal muscle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The skeletal muscle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Skeletal Muscle Lysate

21-197 0.1 mg
EUR 285.5
Description: Monkey (Cynomolgus) skeletal muscle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The monkey (Cynomolgus) skeletal muscle tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the skeletal muscle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The skeletal muscle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Skeletal Muscle Lysate

1375 0.1 mg
EUR 191
Description: Skeletal Muscle tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

MicroRNA Isolation Kit

KS341025 1 kit
EUR 256
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rat Muscle PrimaCell1: Normal Skeletal Muscle Cells

2-82573 1 Kit Ask for price

Rat Ryanodine Receptor 1, Skeletal (RYR1) Protein

20-abx654972
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Troponin-I Rat Skeletal Muscle, pure protein

TNIM50-N-25 25 ug
EUR 225

Rat Skeletal muscle Actinin Alpha ELISA kit

E02S0267-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Skeletal muscle Actinin Alpha ELISA kit

E02S0267-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Skeletal muscle Actinin Alpha ELISA kit

E02S0267-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

cDNA from Rat Normal Tissue: Skeletal Muscle

C1434171 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Troponin I Skeletal Protein

abx060758-100ug 100 ug
EUR 1574

Troponin T Skeletal Protein

abx060767-05mg 0.5 mg
EUR 1713

Skeletal Muscle Cytoplasmic Lysate

XBL-10851 0.1 mg
EUR 227.75
Description: human skeletal muscle tissue cytoplasmic protein lysate was prepared by isolating the cytoplasmic protein from whole tissue homogenates using a proprietary technique. The human skeletal muscle tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The cytoplasmic protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, glycerol, and a cocktail of protease inhibitors. For quality control purposes, the isolated Skeletal Muscle tissue cytoplasmic protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated Skeletal Muscle tissue cytoplasmic protein is then Western analyzed by GAPDH antibody, and the expression level is consistent with each lot.

Skeletal Muscle Membrane Lysate

XBL-10852 0.1 mg
EUR 516.5
Description: human skeletal muscle tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human skeletal muscle tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated Skeletal Muscle tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated Skeletal Muscle tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

anti-fast skeletal Myosin

YF-PA13308 50 ug
EUR 363
Description: Mouse polyclonal to fast skeletal Myosin

anti-fast skeletal Myosin

YF-PA24194 50 ul
EUR 334
Description: Mouse polyclonal to fast skeletal Myosin

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-10x96wellstestplate 10x96-wells test plate
EUR 5124.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-1x48wellstestplate 1x48-wells test plate
EUR 509.64
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-1x96wellstestplate 1x96-wells test plate
EUR 685.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-5x96wellstestplate 5x96-wells test plate
EUR 2783.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

4-SEC773Ra
  • EUR 5175.00
  • EUR 2734.00
  • EUR 686.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Ryanodine Receptor 1, Skeletal ELISA Kit (RYR1)

RK03928 96 Tests
EUR 521

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RD-RYR1-Ra-48Tests 48 Tests
EUR 557

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RD-RYR1-Ra-96Tests 96 Tests
EUR 775

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

DLR-RYR1-Ra-48T 48T
EUR 549
Description: A sandwich quantitative ELISA assay kit for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

DLR-RYR1-Ra-96T 96T
EUR 718
Description: A sandwich quantitative ELISA assay kit for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) CLIA Kit

20-abx493893
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Slow Skeletal Troponin I (TNNI1) CLIA Kit

20-abx494152
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Fast Skeletal Troponin I (TNNI2) CLIA Kit

20-abx494155
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Slow Skeletal Troponin T (TNNT1) CLIA Kit

20-abx494158
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

20-abx156055
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RDR-RYR1-Ra-48Tests 48 Tests
EUR 583

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RDR-RYR1-Ra-96Tests 96 Tests
EUR 811

Rat Ryanodine Receptor 1, Skeletal(RYR1)ELISA Kit

QY-E10032 96T
EUR 361

Genomic DNA from Rat Normal Tissue: Skeletal Muscle

D1434171 100 ug
EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Skeletal Muscle

R1434171-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit

E02M0028-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit

E02M0028-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit

E02M0028-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin Alpha 1, Skeletal Muscle ELISA kit

E02A0391-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin Alpha 1, Skeletal Muscle ELISA kit

E02A0391-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin Alpha 1, Skeletal Muscle ELISA kit

E02A0391-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit

E02A1218-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit

E02A1218-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit

E02A1218-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1172

Mouse Skeletal Muscle Tissue Lysate

LYSATE0021 200ug
EUR 150
Description: This cell lysate is prepared from mouse skeletal muscle tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

? skeletal muscle actin Monoclonal Antibody

EM1149-100ul 100ul
EUR 279
Description: A Mouse Monoclonal antibody against ? skeletal muscle actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

? skeletal muscle actin Monoclonal Antibody

EM1149-50ul 50ul
EUR 207
Description: A Mouse Monoclonal antibody against ? skeletal muscle actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

?-Skeletal Muscle Actin Polyclonal Antibody

EA047-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

?-Skeletal Muscle Actin Polyclonal Antibody

EA047-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

?-Skeletal Muscle Actin Polyclonal Antibody

ES1176-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA

?-Skeletal Muscle Actin Polyclonal Antibody

ES1176-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA

alpha Actin (skeletal muscle) Antibody

35512-100ul 100ul
EUR 390

Rabbit Skeletal Muscle Troponin-C

7-06205 1mg Ask for price

Rabbit Skeletal Muscle Troponin-C

7-06206 5mg Ask for price

Rabbit Skeletal Muscle Troponin-C

7-06207 10mg Ask for price

Troponin I Skeletal Muscle Antibody

abx020870-1mg 1 mg
EUR 815

Troponin I Skeletal Muscle Antibody

abx020871-1mg 1 mg
EUR 815

Troponin I antibody (Skeletal Muscle)

10R-T126a 1 mg
EUR 568
Description: Mouse monoclonal Troponin I antibody (Skeletal Muscle)

Troponin I antibody (Skeletal Muscle)

10R-T126b 1 mg
EUR 568
Description: Mouse monoclonal Troponin I antibody (Skeletal Muscle)

Troponin I antibody (Skeletal Muscle)

10R-T126c 1 mg
EUR 568
Description: Mouse monoclonal Troponin I antibody (Skeletal Muscle)

Troponin I antibody (Skeletal Muscle)

10-T126C 1 mg
EUR 469
Description: Mouse monoclonal Troponin I antibody (Skeletal Muscle)

Troponin I antibody (Skeletal Muscle)

10-T81B 1 mg
EUR 503
Description: Mouse monoclonal Troponin I antibody (Skeletal Muscle)

Troponin I protein (Skeletal muscle)

30-AT48 100 ug
EUR 589
Description: Purified native Human Troponin I protein (Skeletal muscle)

alpha Actin (Skeletal Muscle) (Rabbit)

30R-3107 1 mg
EUR 257
Description: Purified native alpha Actin (Skeletal Muscle) (Rabbit)

alpha Actin (Skeletal Muscle) (Mouse)

30R-3408 500 ug
EUR 1418
Description: Recombinant Mouse Actin, alpha skeletal muscle(Acta1)

Troponin T protein (Skeletal Muscle)

30R-AT042 100 ug
EUR 808
Description: Purified native Human Troponin T protein (Skeletal Muscle)

Troponin I protein (Skeletal Muscle)

30R-AT060 100 ug
EUR 1177
Description: Purified native Troponin I protein (Skeletal Muscle)

Skeletal Muscle Diabetic Disease Lysate

XBL-10369 0.1 mg
EUR 663.5
Description: human skeletal muscle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human skeletal muscle tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the Skeletal Muscle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The Skeletal Muscle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Anti-fast skeletal Myosin (2D9)

YF-MA10603 100 ug
EUR 363
Description: Mouse monoclonal to fast skeletal Myosin

Anti-fast skeletal Myosin (3H3)

YF-MA18264 100 ug
EUR 363
Description: Mouse monoclonal to fast skeletal Myosin

Anti-fast skeletal Myosin (1B22)

YF-MA19700 100 ug
EUR 363
Description: Mouse monoclonal to fast skeletal Myosin

Rat Troponin I, slow skeletal muscle(TNNI1) ELISA kit

CSB-EL024011RA-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin I, slow skeletal muscle (TNNI1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

The results of the analysis of the ontology of genes and the analysis of the channels have shown that the target genes of exosotional exosomal miras in differential way participate in the regulation of various biological processes, such as catalytic activity, the connection protein, metabolic processes, cell development and differentiation, and are enriched in differentiation-related osteogenic differentiation routes, such as MAPK signaling, AMPK signaling and insulin signaling pathways. Our results reveal for the first time that exosomal miracas derived from Osteogenic differentiated PDLSCs can promote Osteogenic Differentiation of BMSCs, which provides a basis for new research on the regulatory function of the exosomal Mijonde of PDLSCs during osteogenesis.