Moderna Spike S Protein
Lab Reagents
Human IgG antibody Laboratories manufactures the moderna spike s protein reagents distributed by Genprice. The Moderna Spike S Protein reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Spike Protein. Other Moderna products are available in stock. Specificity: Moderna Category: Spike Group: S Protein
Recombinant SARS Associated Spike Mosaic S(M) |
|||
7-07096 | CHI Scientific | 100µg | Ask for price |
Recombinant SARS Associated Spike Mosaic S(M) |
|||
7-07097 | CHI Scientific | 500µg | Ask for price |
Recombinant SARS Associated Spike Mosaic S(M) |
|||
7-07098 | CHI Scientific | 1000µg | Ask for price |
Recombinant SARS Associated Spike Mosaic S© |
|||
7-07099 | CHI Scientific | 100µg | Ask for price |
Recombinant SARS Associated Spike Mosaic S© |
|||
7-07100 | CHI Scientific | 500µg | Ask for price |
Recombinant SARS Associated Spike Mosaic S© |
|||
7-07101 | CHI Scientific | 1000µg | Ask for price |
Recombinant (E.Coli) SARS Associated Spike Mosaic S |
|||
RP-1422 | Alpha Diagnostics | 100 ug | EUR 286 |
Recombinant (E.Coli) SARS Associated Spike Mosaic S |
|||
RP-1423 | Alpha Diagnostics | 100 ug | EUR 286 |
Recombinant (E.Coli) SARS Associated Spike Mosaic S |
|||
RP-1424 | Alpha Diagnostics | 100 ug | EUR 286 |
Recombinant Coronavirus Spike Protein (SARS-CoV S, His tag) |
|||
P1520-10 | Biovision | 10µg | EUR 257 |
SARS-CoV-2 (COVID-19) Trimeric Spike (S) Recombinant Protein |
|||
10-075 | ProSci | 0.1 mg | EUR 826.25 |
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is an enveloped, single-stranded, positive-sense RNA virus that belongs to the Coronaviridae family 1. The SARS-CoV-2 genome, which shares 79.6% identity with SARS-CoV, encodes four essential structural proteins: the spike (S), envelope (E), membrane (M), and nucleocapsid protein (N) 2. The S protein is a transmembrane, homotrimeric, class I fusion glycoprotein that mediates viral attachment, fusion, and entry into host cells 3. Each ~180 kDa monomer contains two functional subunits, S1 (~700 a.a) and S2 (~600 a.a), that mediate viral attachment and membrane fusion, respectively. S1 contains two major domains, the N-terminal (NTD) and C-terminal domains (CTD). The CTD contains the receptor-binding domain (RBD), which binds to the angiotensin-converting enzyme 2 (ACE2) receptor on host cells 3-5. Although both SARS-CoV and SARS-CoV-2 bind the ACE2 receptor, the RBDs only share ~73% amino acid identity, and the SARS-CoV-2 RBD binds with a higher affinity compared to SARS-CoV 3, 6. The RBD is dynamic and undergoes hinge-like conformational changes, referred to as the “down” or “up” conformations, which hide or expose the receptor-binding motifs, respectively 7. Following receptor binding, S1 destabilizes, and TMPRSS2 cleaves S2, which undergoes a pre- to post-fusion conformation transition, allowing for membrane fusion 8, 9. The S protein has been the main focus of therapeutic and vaccine design as it is highly immunogenic. Both neutralizing antibodies 10,11 and memory T cells 12,13 targeting the S protein are present in the sera of convalescent COVID-19 patients. |
SARS-CoV-2 (COVID-19) Spike S Trimer Recombinant Protein |
|||
20-182 | ProSci | 0.1 mg | EUR 542.75 |
Description: The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Rabbit Anti-flagellin protein (Fla/FLGN, S. typhimurium) antiserum |
|||
FLGN12-S | Alpha Diagnostics | 100 ul | EUR 469 |
Recombinant SARS Spike Mosaic S Protein (aa 408-470, 540-573) |
|||
VAng-Lsx0056-inquire | Creative Biolabs | inquire | Ask for price |
Description: Recombinant SARS-CoV Spike protein containing 408-470, 540-573 amino acids immunodominant regions was expressed in E. coli and purified by proprietary chromatographic technique. |
SARS-CoV Spike Protein |
|||
abx060655-1mg | Abbexa | 1 mg | EUR 1692 |
Rabbit Anti-Sm28/Smp28/GST28/GST-mu protein (S. Japonicum, 1-211aa) antiserum |
|||
SM282-S | Alpha Diagnostics | 100 ul | EUR 457 |
Rabbit Anti-S. Pneumococcal Serotype 23F Carbohydrate (Spn23F) Antiserum |
|||
SPN231-S | Alpha Diagnostics | 100 ul | EUR 445 |