MicroRNA profile in the squamous cell carcinoma: prognostic and diagnostic roles

CARCINOMES Squamies of the head and neck (HNSCC) are human malignants associated with genetic and environmental factors. Micronas (Mirnas) as a group of non-coding small RNAs has important roles in the development of this type of cancer. Expressions of several MIRNAS have been demonstrated to be increased in HNSCC samples and unclear tissues. In silico forecasting tools and functional analyzes have confirmed the function of some MIRNAS in the modulation of cancer targets, indicating these mirsas like onco-mirs. In addition, many mirnas have been regulated in HNSCC samples. Their targets mainly reinforce cell proliferation or inhibit apoptosis. MIRNAS Signature has practical implications for the diagnosis, staging and management of HNSC.

More particularly, many mIRNAS have been demonstrated to change the response of tumor cells to anticancer drugs such as cisplatin and doxorubicin. Traffic levels of these small transcripts have been suggested as promising biomarkers for the diagnosis of HNSCC. In the current manuscript, we summarize the available literature regarding the MIRNAS signature in HNSCC and their role as diagnostic / prognostic biomarkers. Pulmonary fibrosis is a kind of interstitial pulmonary disease with the architectural remodeling of tissues and excessive matrix deposits.

In addition to the messenger RNA (MRNA), Microna (Mirna), a long non-coding RNA (LNCRNA) and Circular RNA (CIRCRA) could also play an important role in the regulatory processes of the occurrence and progression of Pulmonary fibrosis. In this study, the pulmonary fibrosis model was administered with bleomycin. A total transcriptome sequence analysis has been applied to study the expression profiles. After comparing samples of lung pulmonary fibrosis induced by bleomycin, 286 LNCRNAS, 192 MRNAS, 605 CIRCRNAS and 32 MIRNAS were considered differentially.

Analysis of comparative microarnas expression profiles during embryonic development of common carp, Cyprinus carpio

Micronas (MIRNAS) plays important roles in biological processes by regulating specific gene expression. Limited MIRNAS information is available on embryonic development in the common carp (Cyprinus Carpio) so far. In this study, six important embryonic development steps of C.carpio were collected to perform a series of small RNA-seq experiments from cleavage, blastocyst, gastritiment, organ formation, from the floor. From hatching 1 day of post-hatching larva. MIRNAS expression profiles have been identified and expressed differently from MIRNAS (DEMS) have been filtered on the basis of pair comparison. An average of 12,744,989 gross readings and 9,888,123 clean readings were obtained from each library.

A total of 2565 mirnas have been identified. 68 out of 204 dems were covered with scene-specific mirnas, in which 15 Known Mirnas were known and seemed to play a key role in embryogenesis. In addition, the expression of the hourly route reveals several intriguing fluctuations during embryogenesis. Many signaling pathways have been identified in embryonic development, including phototransucation, the hippo signaling path, WNT, melanogenesis, histidine metabolism and fatty acid biosynthesis. The results would provide new insights into the roles of Mirnas in embryonic development and would help us advance the understanding of Mirna’s mediated mediation mechanisms in the embryonic development of fish.

Myalgic encephalomyelitis / chronic fatigue syndrome (ME / CFS) is a complex chronic disease, rooted in multi-system malfunctions characterized by unexplained debilitating fatigue. Post-exertion malaise (PEM), defined as the exacerbation of patient symptoms after minimal physical or mental stress, is a signal mark of me / CFS. Although several case definitions exist, there is currently no biomarker or well-established laboratory tests to diagnose ME / CFS.

MicroRNA profile in the squamous cell carcinoma: prognostic and diagnostic roles
MicroRNA profile in the squamous cell carcinoma: prognostic and diagnostic roles

The in-circulating microtranscript profiles reveal a distinct expression of micrarnas in severe leptospirosis

Biomarkers predict the severity of theperspirose are still lacking. This study aimed to identify and validate microarnas in patients with severe dupessospirosis, which could potentially be used as biomarkers to predict an unfavorable result. Serum samples were collected from participants with a definitive diagnosis of leptospirosis. Participants were divided into two groups, non-serious and severe leptospirosis, as defined by the specific branch of the sequential organ (sofa) of more than two in any organ. The microtranscriptome analysis was performed using Mirna Nanostring’s expression assay.

Kidney Lysate

21-116 0.1 mg
EUR 342.6
Description: Guinea Pig kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The guinea pig kidney tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Kidney Lysate

21-190 0.1 mg
EUR 342.6
Description: Monkey (Cynomolgus) kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The monkey (Cynomolgus) kidney tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Kidney Lysate

21-405 0.1 mg
EUR 342.6
Description: Porcine kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The porcine kidney tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Kidney Lysate

21-418 0.1 mg
EUR 342.6
Description: Rabbit kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The rabbit kidney tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Mouse Kidney PrimaCell2: Normal Kidney Epithelial Cells

2-82057 1 Kit Ask for price

Rat Kidney PrimaCell2: Normal Kidney Epithelial Cells

2-82556 1 Kit Ask for price

Multiple kidney tumor with kidney tissue array

KD1501a each
EUR 258
Description: Multiple kidney tumor with kidney tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 75 cases/150 cores, replacing KD1501

Kidney carcinoma with matched kidney tissue array

KD244a each
EUR 48
Description: Kidney carcinoma with matched kidney tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing KD244

Kidney cancer with matched kidney tissue array

KD801a each
EUR 258
Description: Kidney cancer with matched kidney tissue array, including pathology grade, TNM and clinical stagr, 40 cases/80 cores, replacing KD801

Human Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells

9-80075 1 x 100 ml Ask for price

MicroRNA Isolation Kit

KS341025 1 kit
EUR 307.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Autobioluminescent Human Kidney Cells (HEK293)

ASE-5902 1 ml
EUR 2004
Description: 6 month

Kidney disease spectrum (kidney cancer progression) tissue array

BC07001 each
EUR 258
Description: Kidney disease spectrum (kidney cancer progression) tissue array, including TNM and pathology grade, 40 cases/80 cores (core size 1.5mm)

Kidney cancer tissue array with normal Kidney tissue

KD2082a each
EUR 474
Description: Kidney cancer tissue array with normal Kidney tissue, including TNM and pathology grade, 96 cases/192 cores, replacing KD2082

Multiple kidney cancer with matched kidney tissue array

KD461 each
EUR 258
Description: Multiple kidney cancer with matched kidney tissue array, including pathology grade, TNM and clinical stage, 23 cases/46 cores

Normal kidney and normal adjacent kidney tissue array

KDN241a each
EUR 138
Description: Normal kidney and normal adjacent kidney tissue array, 24 cases/ 24 cores

Kidney cancer with kidney tissue test tissue array

T071b each
EUR 48
Description: Kidney cancer with kidney tissue test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T071a

Kidney Lupus Lysate

XBL-10357 0.1 mg
EUR 796.2
Description: Human kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human kidney tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Fetal Kidney Lysate

XBL-10408 0.1 mg
EUR 342.6
Description: Fetal human kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The fetal human kidney tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Kidney Membrane Lysate

XBL-10649 0.1 mg
EUR 619.8
Description: Human kidney tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human kidney tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated kidney tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated kidney tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Kidney cancer (CCRCC

KD1201 each
EUR 306
Description: Kidney cancer (CCRCC,PRCC,CRCC)with kidney tissue array,including ISUP Grade, TNM/Stage, 120 cases/120 cores (core size 1.0mm ), (Previous Item# is BC07115b)

Kidney tissue array

KD803b each
EUR 354
Description: Kidney tissue array, 80 cases/80n cores (core size 1.5mm), replacing KD803a

Rat Kidney PrimaCell2: Normal Kidney Epithelial Cells Growth Medium

9-25056 5 x 100 ml Ask for price

Mouse Kidney PrimaCell2: Normal Kidney Epithelial Cells Growth Medium

9-32057 5 x 100 ml Ask for price

Kidney cancer tissue array with adjacent normal kidney tissue

BC07015b each
EUR 168
Description: Kidney cancer tissue array with adjacent normal kidney tissue, including TNM, clinical stage and pathology grade, 72 cases/72 cores, replacing BC07015a

Kidney cancer with matched adjacent normal kidney tissue array

KD603 each
EUR 204
Description: Kidney cancer with matched adjacent normal kidney tissue array, containing metastatic clear cell carcinoma, including pathology grade, TNM and clinical stage (reference AJCC 8th version), 33 cases/61 cores

Human microRNA-210(miR-210)ELISA

QY-E05678 96T
EUR 433.2

hsa-miRNome MicroRNA Profiling Kit [Human]

RA660A-1 20 profiles
EUR 2212.8

Recombinant Human Kidney Associated Antigen 1

7-05422 1µg Ask for price

Recombinant Human Kidney Associated Antigen 1

7-05423 5µg Ask for price

Recombinant Human Kidney Associated Antigen 1

7-05424 50µg Ask for price

Human Kidney OptiTDS1: Tissue Dissociation System

4-28074 1 Kit Ask for price

Human Kidney OptiTDS2: Tissue Dissociation System

4-28075 1 Kit Ask for price

Human Kidney OptiTDS3: Tissue Dissociation System

4-28076 1 Kit Ask for price

Human Kidney OptiTDS4: Tissue Dissociation System

4-28077 1 Kit Ask for price

Human Kidney OptiTDS5: Tissue Dissociation System

4-28078 1 Kit Ask for price

Human Kidney OptiTDS6: Tissue Dissociation System

4-28079 1 Kit Ask for price

Human Kidney OptiTDS7: Tissue Dissociation System

4-28080 1 Kit Ask for price

Human Cancer PrimaCell9: Kidney Tumor Cells

2-96032 1 Kit Ask for price

Human Kidney PrimaCell4: Normal Renal Firbroblasts

2-96077 1 Kit Ask for price

Human Kidney PrimaCell6: Normal Renal Podocytes

2-96079 1 Kit Ask for price

Human Glutaminase kidney isoform, mitochondrial (GLS)

1-CSB-EP009528HU(F)
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Glutaminase kidney isoform, mitochondrial(GLS),partial expressed in E.coli

Human Glutaminase kidney isoform, mitochondrial (GLS)

1-CSB-EP009528HU(F1)
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Glutaminase kidney isoform, mitochondrial(GLS),partial expressed in E.coli

cDNA from Human Tumor Tissue: Kidney

C1235142 40 reactions
EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Kidney

C1236142Dia 40 reactions
EUR 801.6
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Paraffin Tissue Section - Human Kidney Tumor

T2235142 5 slides
EUR 308.4
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Section - Human Tumor: Kidney

T1235142 5 slides
EUR 405.6
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1406.4

Mouse Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells

9-80171 1 x 100 ml Ask for price

Rat Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells

9-80263 1 x 100 ml Ask for price

Kidney cancer tissue array with matched cancer adjacent kidney tissue

KD2601a each
EUR 354
Description: Kidney cancer tissue array with matched cancer adjacent kidney tissue,including TNM, clinical stage and pathology grade, 65 cases/ 260 cores, replacing KD2061

Kidney tumor tissue array with matched tumor adjacent kidney tissue

KD2602a each
EUR 354
Description: Kidney tumor tissue array with matched tumor adjacent kidney tissue, including TNM, clinical stage and pathology grade, 65 cases/260 cores, replacing KD2602

Kidney clear cell carcinoma with matched adjacent kidney tissue array

KD486 each
EUR 168
Description: Kidney clear cell carcinoma with matched adjacent kidney tissue array, including TNM and pathology grade, 16 cases/48 cores

Kidney cancer tissue array with matched adjacent normal kidney tissue

KD901a each
EUR 258
Description: Kidney cancer tissue array with matched adjacent normal kidney tissue, including TNM, clinical stage and pathology grade, 40 cases/90 cores, replacing KD901

Kidney Tissue Slide (Normal)

10-401-10um 10 um
EUR 241.8

Kidney Tissue Slide (Normal)

10-401-4um 4 um
EUR 216.6

Kidney Tissue Slide (Tumor)

10-402-10um 10 um
EUR 241.8

Kidney Tissue Slide (Tumor)

10-402-4um 4 um
EUR 216.6

Kidney Tissue Slide (Abnormal)

10-455-10um 10 um
EUR 241.8

Kidney Tissue Slide (Abnormal)

10-455-4um 4 um
EUR 216.6

Kidney Tissue Lysate (Normal)

1706-02 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Normal)

1706-03 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Normal)

1706-04 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Normal)

1706-05 0.1 mg
EUR 260.7
Description: Kidney tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-01 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-02 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-03 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-04 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-05 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-06 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-07 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-08 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1707-09 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1708-01 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1708-02 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1708-03 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1709-01 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1709-02 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Kidney Tissue Lysate (Tumor)

1709-03 0.1 mg
EUR 336.3
Description: Kidney tumor tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

cDNA from hypertension: Kidney

C1236142Hd-2 40 reactions
EUR 801.6
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Kidney

C1236142Lup 40 reactions
EUR 801.6
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Kidney Tissue Lysate

LYSATE0006 200ug
EUR 180
Description: This cell lysate is prepared from rat kidney tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Mouse Kidney Tissue Lysate

LYSATE0016 200ug
EUR 180
Description: This cell lysate is prepared from mouse kidney tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Plastic Kidney Bowl 252mm

INS6272 EACH
EUR 6.84

Kidney Liver Cirrhosis Lysate

XBL-10356 0.1 mg
EUR 796.2
Description: Human kidney tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human kidney tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the kidney tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The kidney tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Fetal Kidney Cytoplasmic Lysate

XBL-10657 0.1 mg
EUR 273.3
Description: Human kidney tissue cytoplasmic protein lysate was prepared by isolating the cytoplasmic protein from whole tissue homogenates using a proprietary technique. The fetal human kidney tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The cytoplasmic protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, glycerol, and a cocktail of protease inhibitors. For quality control purposes, the isolated kidney tissue cytoplasmic protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated kidney tissue cytoplasmic protein is then Western analyzed by GAPDH antibody, and the expression level is consistent with each lot.

Kidney Membrane Tumor Lysate

XBL-10661 0.1 mg
EUR 752.1
Description: Human kidney tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human kidney tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated kidney tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated kidney tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Mouse Kidney Nuclear Extract

X12011 500 µg Ask for price

Kidney cancer tissue array

BC07014b each
EUR 168
Description: Kidney cancer tissue array, including pathology grade, TNM and clinical stage, 72 cases/72 cores, replacing BC07014a

Kidney cancer tissue array

KD245 each
EUR 66
Description: Kidney cancer tissue array, including TNM, clinical stage and pathology grade, 24 cases/ 24 cores

Kidney cancer tissue array

KD485 each
EUR 168
Description: Kidney cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores

Normal kidney tissue array

KD803 each
EUR 354
Description: Normal kidney tissue array, replacing BN07012, 80 cases/80 cores

Normal kidney tissue array

KDN242 each
EUR 72
Description: Normal kidney tissue array, 24 cases/24 cores

Human pre-microRNA Expression Construct 146a-2

PMIRH146a-PA-2 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct Lentimir-29a

PMIRH29aPA-2 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct let-7b

PMIRHlet7bPA-1 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct let-7c

PMIRHlet7cPA-1 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct let-7d

PMIRHlet7dPA-1 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct let-7e

PMIRHlet7ePA-1 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct let-7g

PMIRHlet7gPA-1 Bacterial Streak
EUR 820.8

Human pre-microRNA Expression Construct let-7i

PMIRHlet7iPA-1 Bacterial Streak
EUR 820.8

Multiple kidney cancer with matched tumor adjacent (AT) kidney tissue array

KD702a each
EUR 234
Description: Multiple kidney cancer with matched tumor adjacent (AT) kidney tissue array, 35 cases/70 cores, including CCRCC (15 cases), PRCC (9 cases), CHRCC (8 cases), ccpRCC (3 cases)

Multiple kidney disease with kidney tissue array (2016/ISUP WHO classification

KD804a each
EUR 258
Description: Multiple kidney disease with kidney tissue array (2016/ISUP WHO classification, Grade mean Isup Grade), including pathoogy grade, TNM and clinical stage (reference AJCC 8th version), 75 cases/80 cores, replacing KD804

Human Kidney PrimaCell1: Normal Glomerular Endothelial Cells

2-96074 1 Kit Ask for price

Human Kidney PrimaCell5: Normal Renal Mesangial Cells

2-96078 1 Kit Ask for price

Human Kidney PrimaCell 8: Proximal Tubular Cells

2-96120 1 Kit Ask for price

Human Kidney Injury Molecule 1 (Kim1) Protein

20-abx168665
  • EUR 644.40
  • EUR 292.80
  • EUR 1880.40
  • EUR 760.80
  • EUR 477.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Kidney Injury Molecule 1 (Kim1) Protein

20-abx067643
  • EUR 644.40
  • EUR 292.80
  • EUR 1880.40
  • EUR 760.80
  • EUR 477.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Kidney mitochondrial carrier protein 1 (SLC25A30)

1-CSB-EP732909HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Kidney mitochondrial carrier protein 1(SLC25A30) expressed in E.coli

cDNA from Human Adult Normal Tissue: Kidney

C1234142 40 reactions
EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Kidney Injury Molecule 1 ELISA kit

E01K0025-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Kidney Injury Molecule 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kidney Injury Molecule 1 ELISA kit

E01K0025-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Kidney Injury Molecule 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kidney Injury Molecule 1 ELISA kit

E01K0025-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Kidney Injury Molecule 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Total Protein from Human Tumor Tissue: Kidney

P1235142 1 mg
EUR 384
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Diabetic Tissue: Kidney

P1236142Dia 1 mg
EUR 553.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Human Adult Kidney (Normal) Whole tissue lysate

HAL-1305 1 mg
EUR 628.8

Human 293, transformed primary embryonal kidney lysate

HCL-1210 100ug
EUR 255.6

Human Kidney Slide (Normal) (5 slides/pk)

HTS-10401 1 pk
EUR 343.2

Human Kidney Slide (Tumor) (5 slides/pk)

HTS-10402 1 pk
EUR 343.2

Human Kidney Slide (Abnormal) (5 slides/pk)

HTS-10455 1 pk
EUR 343.2

Human liver kidney microsome autoantibody ELISA Kit

ELA-E1133h 96 Tests
EUR 988.8

Membrane Protein from Human Tumor Tissue: Kidney

P3235142 0.1 mg
EUR 489.6
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Paraffin Tissue Section - Human Adult Normal: Kidney

T2234142 5 slides
EUR 253.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Section - Human Adult Normal: Kidney

T1234142 5 slides
EUR 418.8
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Section - Human Diabetic Tissue: Kidney

T1236142Dia 5 slides
EUR 558
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Total RNA from Human Tumor Tissue: Kidney

R1235142-50 50 ug
EUR 421.2
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Cadherin, Fetal Kidney(KCAD)ELISA Kit

QY-E01335 96T
EUR 433.2

MicroRNA scramble in CD511 - Virus

PMIRH000VA-1 1x10^6 IFUs
EUR 937.2

MicroRNA Precursor Pooled Plasmid Library

PMIRHPLPA-1 1 aliquot plasmid DNA
EUR 60

The level of expression of the Mirnas candidate was then validated by Quantitative RT-PCR. Based on the nanostring, the microtrascriptome profile of the group was significantly different from that of the non-serious group. Regulation of MIR155-5P, MIR362-3P, MIR502-5P, MIR601, MIR1323 and MIR630 in the group have been identified and further studied. A total of 119 participants were enrolled in the validation cohort. The serum mIR155-5P and MIR630 levels were significantly higher in the Severe Group compared to the non-serious group. The combined use of MIR155-5P or MIR-630 with serum bicarbonate levels had an ACV of 0.79 (95% ci; 0.69-0.89, p <0.001) to identify the severity of the disease. These data provide the first evidence that microTranscript profiles of patients with severe dupessospirosis were different from the non-severe group. Serum mir155-5P and MIR630 levels can be new biomarkers to identify severe ceptospirosis.