MicroRNA profile in the squamous cell carcinoma: prognostic and diagnostic roles
CARCINOMES Squamies of the head and neck (HNSCC) are human malignants associated with genetic and environmental factors. Micronas (Mirnas) as a group of non-coding small RNAs has important roles in the development of this type of cancer. Expressions of several MIRNAS have been demonstrated to be increased in HNSCC samples and unclear tissues. In silico forecasting tools and functional analyzes have confirmed the function of some MIRNAS in the modulation of cancer targets, indicating these mirsas like onco-mirs. In addition, many mirnas have been regulated in HNSCC samples. Their targets mainly reinforce cell proliferation or inhibit apoptosis. MIRNAS Signature has practical implications for the diagnosis, staging and management of HNSC.
More particularly, many mIRNAS have been demonstrated to change the response of tumor cells to anticancer drugs such as cisplatin and doxorubicin. Traffic levels of these small transcripts have been suggested as promising biomarkers for the diagnosis of HNSCC. In the current manuscript, we summarize the available literature regarding the MIRNAS signature in HNSCC and their role as diagnostic / prognostic biomarkers. Pulmonary fibrosis is a kind of interstitial pulmonary disease with the architectural remodeling of tissues and excessive matrix deposits.
In addition to the messenger RNA (MRNA), Microna (Mirna), a long non-coding RNA (LNCRNA) and Circular RNA (CIRCRA) could also play an important role in the regulatory processes of the occurrence and progression of Pulmonary fibrosis. In this study, the pulmonary fibrosis model was administered with bleomycin. A total transcriptome sequence analysis has been applied to study the expression profiles. After comparing samples of lung pulmonary fibrosis induced by bleomycin, 286 LNCRNAS, 192 MRNAS, 605 CIRCRNAS and 32 MIRNAS were considered differentially.
Analysis of comparative microarnas expression profiles during embryonic development of common carp, Cyprinus carpio
Micronas (MIRNAS) plays important roles in biological processes by regulating specific gene expression. Limited MIRNAS information is available on embryonic development in the common carp (Cyprinus Carpio) so far. In this study, six important embryonic development steps of C.carpio were collected to perform a series of small RNA-seq experiments from cleavage, blastocyst, gastritiment, organ formation, from the floor. From hatching 1 day of post-hatching larva. MIRNAS expression profiles have been identified and expressed differently from MIRNAS (DEMS) have been filtered on the basis of pair comparison. An average of 12,744,989 gross readings and 9,888,123 clean readings were obtained from each library.
A total of 2565 mirnas have been identified. 68 out of 204 dems were covered with scene-specific mirnas, in which 15 Known Mirnas were known and seemed to play a key role in embryogenesis. In addition, the expression of the hourly route reveals several intriguing fluctuations during embryogenesis. Many signaling pathways have been identified in embryonic development, including phototransucation, the hippo signaling path, WNT, melanogenesis, histidine metabolism and fatty acid biosynthesis. The results would provide new insights into the roles of Mirnas in embryonic development and would help us advance the understanding of Mirna’s mediated mediation mechanisms in the embryonic development of fish.
Myalgic encephalomyelitis / chronic fatigue syndrome (ME / CFS) is a complex chronic disease, rooted in multi-system malfunctions characterized by unexplained debilitating fatigue. Post-exertion malaise (PEM), defined as the exacerbation of patient symptoms after minimal physical or mental stress, is a signal mark of me / CFS. Although several case definitions exist, there is currently no biomarker or well-established laboratory tests to diagnose ME / CFS.
The in-circulating microtranscript profiles reveal a distinct expression of micrarnas in severe leptospirosis
Biomarkers predict the severity of theperspirose are still lacking. This study aimed to identify and validate microarnas in patients with severe dupessospirosis, which could potentially be used as biomarkers to predict an unfavorable result. Serum samples were collected from participants with a definitive diagnosis of leptospirosis. Participants were divided into two groups, non-serious and severe leptospirosis, as defined by the specific branch of the sequential organ (sofa) of more than two in any organ. The microtranscriptome analysis was performed using Mirna Nanostring’s expression assay.
Human Liver Kidney Microsome Autoantibody ELISA Kit |
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| MBS037709-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human Liver Kidney Microsome Autoantibody ELISA Kit |
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| MBS037709-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human Liver Kidney Microsome Autoantibody ELISA Kit |
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| MBS037709-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human Liver kidney microsome autoantibody ELISA Kit |
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| MBS726147-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Human Liver kidney microsome autoantibody ELISA Kit |
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| MBS726147-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Human Liver kidney microsome autoantibody ELISA Kit |
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| MBS726147-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Human Liver kidney microsome autoantibody ELISA Kit |
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| MBS726147-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Human microRNA-210(miR-210)ELISA |
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| QY-E05678 | Qayee Biotechnology | 96T | EUR 433.2 |
Human liver kidney microsome autoantibody,LKM ELISA Kit |
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| CN-03585H1 | ChemNorm | 96T | EUR 560.4 |
Human liver kidney microsome autoantibody,LKM ELISA Kit |
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| CN-03585H2 | ChemNorm | 48T | EUR 379.2 |
Human liver kidney microsome autoantibody,LKM ELISA Kit |
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| YLA1220HU-48T | Shanghai YL Biotech | 48T | Ask for price |
Human liver kidney microsome autoantibody,LKM ELISA Kit |
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| YLA1220HU-96T | Shanghai YL Biotech | 96T | Ask for price |
Human liver kidney microsome autoantibody(LKM)ELISA Kit |
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| GA-E0583HM-48Tests | GenAsia Biotech | 48 Tests | Ask for price |
Human liver kidney microsome autoantibody(LKM)ELISA Kit |
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| GA-E0583HM-96Tests | GenAsia Biotech | 96 Tests | EUR 388 |
Human liver kidney microsome autoantibody(LKM)ELISA Kit |
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| GA-E0583HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human liver kidney microsome autoantibody(LKM)ELISA Kit |
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| GA-E0583HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human liver kidney microsome autoantibody(LKM)ELISA Kit |
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| QY-E02647 | Qayee Biotechnology | 96T | EUR 472.8 |
Human liver kidney microsome autoantibody,LKM ELISA Kit |
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| SL1088Hu | Sunlong | 96 Tests | EUR 468 |
Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit |
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| MBS3800844-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit |
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| MBS3800844-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit |
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| MBS3800844-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit |
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| MBS3800844-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human liver kidney microsome autoantibody,LKM ELISA Kit |
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| 201-12-0567 | Shanghai Sunred Biological Technology | 96 tests | EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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Human liver / kidney microsomal autoantibody (LKM) ELISA Kit |
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| MBS263743-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3040 |
Human liver / kidney microsomal autoantibody (LKM) ELISA Kit |
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| MBS263743-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human liver / kidney microsomal autoantibody (LKM) ELISA Kit |
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| MBS263743-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1670 |
Human liver / kidney microsomal autoantibody (LKM) ELISA Kit |
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| MBS263743-96StripWells | MyBiosource | 96-Strip-Wells | EUR 405 |
Human liver/kidney microsomal autoantibody(LKM) ELISA Kit |
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| EIA05971h | Enlibio | each | EUR 430 |
Human liver/kidney microsomal auto antibody(LKM) ELISA Kit |
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| NSL1876Hu | Sunlong | 96 wells | EUR 468 |
Human microrna-21(mir-21) ELISA Kit |
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| SL3405Hu | Sunlong | 96 Tests | EUR 468 |
Human MicroRNA-210 (miR-210) ELISA Kit |
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| MBS3800168-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human MicroRNA-210 (miR-210) ELISA Kit |
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| MBS3800168-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human MicroRNA-210 (miR-210) ELISA Kit |
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| MBS3800168-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human MicroRNA-210 (miR-210) ELISA Kit |
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| MBS3800168-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human liver kidney microsome autoantibody,LKM Ab ELISA KIT |
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| E0566Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human liver kidney microsome autoantibody,LKM Ab ELISA KIT |
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| E0566Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human liver kidney microsome autoantibody,LKM Ab ELISA KIT |
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| E0566Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human liver kidney microsome autoantibody,LKM Ab ELISA KIT |
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| E0566Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human liver kidney microsome type 1 antibody(IgG) Elisa Kit |
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| EK714243 | AFG Bioscience LLC | 96 Wells | EUR 0.44 |
Human liver kidney microsome type 1 antibody(IgG) ELISA Kit |
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| CSB-E09074h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Qualitativeindirect ELISA kit for measuring Human liver kidney microsome type 1 antibody (IgG) in samples from serum. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human liver kidney microsome type 1 antibody(IgG) ELISA Kit |
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| 1-CSB-E09074h | Cusabio |
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Description: Qualitativeindirect ELISA kit for measuring Human liver kidney microsome type 1 antibody(IgG) in samples from serum. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Human liver kidney microsome type 1 antibody,IgG ELISA KIT |
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| ED0355Hu | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human liver kidney microsome type 1 antibody, IgG ELISA Kit |
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| MBS1610674-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3460 |
Human liver kidney microsome type 1 antibody, IgG ELISA Kit |
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| MBS1610674-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1750 |
Human liver kidney microsome type 1 antibody, IgG ELISA Kit |
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| MBS1610674-96StripWells | MyBiosource | 96-Strip-Wells | EUR 425 |
Human Anti-Liver Kidney Microsome Type 1 IgG (LKM1) ELISA Kit |
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| abx352171-96tests | Abbexa | 96 tests | EUR 943.2 |
Human Antibodies Liver Kidney microsomes,Anti-LKM-1 ELISA KIT |
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| ED0575Hu | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
hsa-miRNome MicroRNA Profiling Kit [Human] |
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| RA660A-1 | SBI | 20 profiles | EUR 2212.8 |
Liver Kidney Microsome Type 1 Antibody (IgG) (Human) ELISA Kit (OKCA00483) |
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| OKCA00483 | Aviva Systems Biology | 96 Wells | EUR 1030.8 |
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Description: Description of target: Liver Kidney Microsome Type 1 Antibody (IgG);Species reactivity: Human;Application: ;Assay info: Assay Methodology: Qualitative Reverse Capture ELISA;Sensitivity: |
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Expression Plasmid of Human microRNA MIR670 |
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| SC402151 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR676 |
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| SC402196 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR711 |
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| SC402344 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR718 |
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| SC402364 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR759 |
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| SC402366 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR761 |
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| SC402367 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR762 |
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| SC402368 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR764 |
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| SC402369 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA LET7B |
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| SC400004 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA LET7c |
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| SC400005 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA LET7d |
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| SC400006 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA LET7e |
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| SC400007 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA LET7g |
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| SC400010 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA LET7i |
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| SC400011 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR17 |
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| SC400201 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR21 |
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| SC400271 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR22 |
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| SC400286 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR25 |
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| SC400298 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR28 |
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| SC400304 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR31 |
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| SC400328 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR32 |
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| SC400329 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR93 |
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| SC400685 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR95 |
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| SC400702 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR96 |
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| SC400703 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression plasmid for human microRNA MIR98 |
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| SC400704 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR23c |
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| SC401291 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR466 |
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| SC401800 | Origene Technologies GmbH | 10 µg | Ask for price |
Human Anti-LKM1(Anti-Liver Kidney Microsomal type 1 IgG) ELISA Kit |
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| ELK0814-48T | ELK Biotech | 48T | Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Anti-LKM1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Anti-LKM1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Anti-LKM1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Anti-LKM1 in the samples is then determined by comparing the OD of the samples to the standard curve. |
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Human Anti-LKM1(Anti-Liver Kidney Microsomal type 1 IgG) ELISA Kit |
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| ELK0814-96T | ELK Biotech | 96T | Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Anti-LKM1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Anti-LKM1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Anti-LKM1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Anti-LKM1 in the samples is then determined by comparing the OD of the samples to the standard curve. |
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Human Anti-LKM1 (Anti-Liver Kidney Microsomal type 1 IgG) ELISA Kit |
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| MBS8820188-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3130 |
Human Anti-LKM1 (Anti-Liver Kidney Microsomal type 1 IgG) ELISA Kit |
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| MBS8820188-48StripWells | MyBiosource | 48-Strip-Wells | EUR 350 |
Human Anti-LKM1 (Anti-Liver Kidney Microsomal type 1 IgG) ELISA Kit |
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| MBS8820188-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1710 |
Human Anti-LKM1 (Anti-Liver Kidney Microsomal type 1 IgG) ELISA Kit |
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| MBS8820188-96StripWells | MyBiosource | 96-Strip-Wells | EUR 445 |
Expression Plasmid of Human microRNA MIR4661 |
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| SC401802 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4663 |
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| SC401805 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4664 |
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| SC401806 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4665 |
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| SC401807 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4667 |
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| SC401810 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4668 |
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| SC401811 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4669 |
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| SC401812 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4670 |
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| SC401813 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4671 |
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| SC401814 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4672 |
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| SC401815 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4673 |
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| SC401816 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4674 |
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| SC401817 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4675 |
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| SC401818 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4676 |
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| SC401819 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4677 |
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| SC401820 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4678 |
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| SC401821 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4680 |
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| SC401824 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4681 |
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| SC401825 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4682 |
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| SC401826 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4683 |
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| SC401827 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4684 |
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| SC401828 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4685 |
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| SC401829 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4686 |
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| SC401830 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4687 |
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| SC401831 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4688 |
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| SC401832 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4689 |
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| SC401833 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4690 |
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| SC401834 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4691 |
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| SC401835 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4692 |
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| SC401836 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4693 |
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| SC401837 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4694 |
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| SC401838 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4695 |
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| SC401839 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4696 |
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| SC401840 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4697 |
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| SC401841 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4698 |
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| SC401842 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4699 |
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| SC401843 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4700 |
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| SC401844 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4701 |
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| SC401845 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4703 |
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| SC401846 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4704 |
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| SC401847 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4705 |
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| SC401848 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4706 |
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| SC401849 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4707 |
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| SC401850 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4708 |
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| SC401851 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4709 |
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| SC401852 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4710 |
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| SC401853 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4711 |
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| SC401854 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4712 |
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| SC401855 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4713 |
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| SC401856 | Origene Technologies GmbH | 10 µg | Ask for price |
Expression Plasmid of Human microRNA MIR4714 |
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| SC401857 | Origene Technologies GmbH | 10 µg | Ask for price |
The level of expression of the Mirnas candidate was then validated by Quantitative RT-PCR. Based on the nanostring, the microtrascriptome profile of the group was significantly different from that of the non-serious group. Regulation of MIR155-5P, MIR362-3P, MIR502-5P, MIR601, MIR1323 and MIR630 in the group have been identified and further studied. A total of 119 participants were enrolled in the validation cohort. The serum mIR155-5P and MIR630 levels were significantly higher in the Severe Group compared to the non-serious group. The combined use of MIR155-5P or MIR-630 with serum bicarbonate levels had an ACV of 0.79 (95% ci; 0.69-0.89, p <0.001) to identify the severity of the disease. These data provide the first evidence that microTranscript profiles of patients with severe dupessospirosis were different from the non-severe group. Serum mir155-5P and MIR630 levels can be new biomarkers to identify severe ceptospirosis.