Circulating MicroRNA Expression Profiles in Patients with Stable and Unstable Angina

Objective: High incidence of and deaths from unstable angina (UA) is, for the most part, a consequence of the lack of highly sensitive and specific non-invasive markers. Circulating microRNAs (miRNAs) have been widely recommended as potential biomarkers for various diseases. In this study, we characterized the typical miRNA expression profile in patients with stable angina (SA), UA, and normal coronary arteries (NCA), and identify promising candidates for the diagnosis of UA.


Methods: Serum collected from patients with SA, UA, and NCA who visited the Department of Cardiovascular Diseases Meizhou People’s Hospital. Small RNA sequencing performed on the Illumina HiSeq 2500 platform. MiRNA expression in different groups of patients profiled and then confirmed by that in an independent set of patients. The function of miRNAs are expressed differently allegedly using gene ontology classification and Kyoto Encyclopedia of Genes and Genomes pathway analysis.


Results: Our results suggest that circulating miRNA expression profiles differ between SA, UA, and patient NCA. A total of 36 and 161 miRNAs are dysregulated in SA and UA patients, respectively. validated miRNA

expression by reverse transcription quantitative polymerase chain reaction.
Conclusion: The results showed that circulating miRNAs are potential biomarkers UA. There is a positive correlation between birth weight and BMI pregestational pregnant individuals (r = 0.48, P <0.001). One hundred and eight miRNAs were differentially expressed between normal and overweight / obese group, which target genes are enriched in the metabolic pathways.

C19MC five miRNAs (miR-516a-5p, miR-516b-5p, miR-520A-3p, miR-1323, mir-523-5p) were upregulated in overweight / obese group. Target enrichment analysis indicates their involvement in the post-embryonic development, lipid and glucose homeostasis, differentiation of T cells and the development of the nervous system.

 Circulating MicroRNA Expression Profiles in Patients with Stable and Unstable Angina
Circulating MicroRNA Expression Profiles in Patients with Stable and Unstable Angina

Circulating microRNAs profile variant transthyretin amyloidosis patients

Variant transthyretin amyloidosis (ATTRv) is a rare autosomal dominant disease characterized by the accumulation of amyloid in many organs, most cause sensory-motor neuropathy, cardiomyopathy, and dysautonomia. The purpose of this study was to report the profiles of microRNAs (miRNAs) expression ATTRv identified in patients’ blood.

ATTRv ten patients, 10 asymptomatic carriers of the variant transthyretin (TTRv), 10 patients with Charcot-Marie-Tooth disease (CMT), and 10 healthy controls were studied. Human Schwann cell cultures were used to study the regulation of miR-150-5p effect on the expression of cAMP response element-binding protein (CREB), brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF).

ATTRv patients had 33 miRNAs up-regulated and 48 down-regulated compared to healthy controls; 9 miRNAs up-and-regulated and 30 down-regulated compared CMT patients; 19 miRNAs up-and-regulated and 38 down-regulated compared TTRv asymptomatic carriers. Twelve of the 19 miRNAs upregulated have fold higher than 100. The validation study showed miR-150-5p as a valuable biomarker for patients ATTRv TTRv distinguish from asymptomatic carriers (AUC: 0.9728; p <0.0001).

Rat SeraMir Exosome RNA 384 microRNA qPCR Profiler Assay Set

RA812A-1 20 profiles
EUR 469

Mouse SeraMir Exosome RNA 384 microRNA qPCR Profiler Assay Set (20 assays)

RA811A-1 20 profiles
EUR 469

Lung cancer tissue array

NSC151 each
EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array

NSC153 each
EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array

NSC154 each
EUR 420
Description: Lung cancer tissue array, with ALK results,, 150 cases/150 cores

Lung cancer tissue array

NSC155 each
EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array

NSC156 each
EUR 420
Description: Lung cancer tissue array, 150 cases/150 cores

Lung cancer tissue array

NSC157 each
EUR 420
Description: Lung cancer tissue array, 150 cases/150 cores

Lung cancer tissue array

LC1261 each
EUR 354
Description: Lung cancer tissue array, including pathology grade, TNM, clinical stage and PD-L1 (Sp263) information, 63 cases/126 cores

Lung cancer tissue array

LC243 each
EUR 198
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Lung cancer tissue array

LC485 each
EUR 198
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores

Lung cancer tissue array

LUN703 each
EUR 198
Description: Lung cancer tissue array,including pathology grade and TNM,7 cases/70 cores (core size 1.5mm)

Lung cancer tissue array

LC726b each
EUR 222
Description: Lung cancer tissue array, including TNM, clinical stage and pathology grade, 72 cases/72 cores, replacing LC726

Lung cancer tissue array

LC721 each
EUR 270
Description: Lung cancer tissue array, including TNM and pathology grade, 24 cases/72 cores

Lung cancer tissue array

VLC11 each
EUR 66
Description: Lung cancer tissue array, with TNM and grade info, 11 cases/11 cores

Lung cancer tissue array

VLC12b each
EUR 66
Description: Lung cancer tissue array, including pathology grade, TNM and clinical stage, 12 cases/12 cores, replacing VLC12a

Colon cancer and lung cancer tissue array

CLC601 each
EUR 306
Description: Colon cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores

Colon cancer tissue array

CRM1503 each
EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colon cancer tissue array

CRM1504 each
EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colon cancer tissue array

CRM1506 each
EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colon cancer tissue array

CRM1507 each
EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colon cancer tissue array

CO1502 each
EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Colon cancer tissue array

CO1503 each
EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Colon cancer tissue array

CO244 each
EUR 270
Description: Colon cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Colon cancer tissue array

CO485 each
EUR 270
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/48 cores

Colon cancer tissue array

CO486a each
EUR 414
Description: Colon cancer tissue array, including pathology grade, TNM and clinical stage, 2 serial sections, 48 cases/96 cores, replacing CO486

Colon cancer tissue array

CO641 each
EUR 258
Description: Colon cancer tissue array, including TNM, stage and pathology grade, 64 cases/ 64 cores

Colon cancer tissue array

CO804b each
EUR 270
Description: Colon cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores, replcing CO804a

Colon cancer tissue array

CO901a each
EUR 306
Description: Colon cancer tissue array, with adjacent normal colon tissue, including TNM, clinical stage and pathology grade, 50 cases/90 cores, replacing CO901

Colon cancer tissue array

CO961 each
EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Colon cancer tissue array

CO962 each
EUR 258
Description: Colon cancer tissue array, including pathology grade, TNM/Stage, 48 cases/96 cores

Liver cancer tissue array

LV1002 each
EUR 306
Description: Liver cancer tissue array, including TNM, clinical stage and pathology grade, 50 cases/100 cores

Liver cancer tissue array

LV1502 each
EUR 258
Description: Liver cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Liver cancer tissue array

LV2161 each
EUR 546
Description: Liver cancer tissue array, with normal tissue, including TNM and pathology grade, 216 cases/216 cores

Liver cancer tissue array

LV245 each
EUR 198
Description: Liver cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Vulva cancer tissue array

UV241a each
EUR 66
Description: Vulva cancer tissue array, including TNM, clinical stage and pathology diagnosis, replacing UV241

Liver cancer tissue array

T031c each
EUR 66
Description: Liver cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24cores(1,5mm), replacing T031b

Stomach cancer and lung cancer tissue array

SLC601 each
EUR 306
Description: Stomach cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores

Kidney cancer tissue array

BC07014b each
EUR 168
Description: Kidney cancer tissue array, including pathology grade, TNM and clinical stage, 72 cases/72 cores, replacing BC07014a

Breast cancer tissue array

BR042b each
EUR 78
Description: Breast cancer tissue array, including TNM and pathology grade, 4 cases/4 cores, replacing BR042a

Breast cancer tissue array

BR1006a each
EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 50 cases/100 cores (core size 1.0mm), replacing BR1006

Breast cancer tissue array

BR1141a each
EUR 354
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, IHC marker (ER, PR, HER2 and Ki-67), 114 cases/114 cores, replacing BR1141

Breast cancer tissue array

BR1401 each
EUR 414
Description: Breast cancer tissue array, including TNM and pathology grade, IHC markers ER/PR/Her-2 results, 140 cases/140 cores (core size 1.0mm)

Breast cancer tissue array

BR1503f each
EUR 306
Description: Breast cancer tissue array, including TNM and pathology grade, with IHC results of Her-2\ER\PR\Ki67, 75 cases/ 150 cores, replacing BR1503e

Breast cancer tissue array

BR1505e each
EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage, and IHC(HER2/ER/PR/Ki67), 75 cases/150 cores, replacing BR1505d

Breast cancer tissue array

BR2161 each
EUR 546
Description: Breast cancer tissue array, including TNM and pathology grade, 216 cases/216 cores

Breast cancer tissue array

BR247a each
EUR 234
Description: Breast cancer tissue array, with normal tissue, including TNM and pathology grade, IHC marker (HER2), 24 cases/48 cores replacing BR247

Breast cancer tissue array

BR488 each
EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage (AJCC 7th edition), and IHC marker(ER,PR,Her-2), 48 cases/48 cores

Breast cancer tissue array

BR501 each
EUR 270
Description: Breast cancer tissue array, including TNM and pathology grade, 50 cases/ 50 cores (core size 1.5mm)

Breast cancer tissue array

BR8015a each
EUR 306
Description: Breast cancer tissue array, with adjacent normal tissue and normal tissue, including TNM and pathology grade, 80 cases/80 cores, replacing BC08014

Breast cancer tissue array

BR964 each
EUR 222
Description: Breast cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Kidney cancer tissue array

KD245 each
EUR 66
Description: Kidney cancer tissue array, including TNM, clinical stage and pathology grade, 24 cases/ 24 cores

Kidney cancer tissue array

KD485 each
EUR 168
Description: Kidney cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores

Rectum cancer tissue array

RE1503 each
EUR 258
Description: Rectum cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Breast cancer tissue array

T089c each
EUR 48
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores(1.5mm), replacing T089b

Cervix cancer tissue array

T104a each
EUR 48
Description: Cervix cancer tissue array, including squamous cell carcinoma, glassy cell carcinoma and adenocarcinoma, pathology grade, TNM and clinical stage, 6 cases/24 cores (1.5mm), replacing T104

Colon cancer test tissue array (4x (2x3) array)

T055a each
EUR 48
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055

Colon cancer test tissue array (4x (2x3) array)

T055b each
EUR 48
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055a

Bladder cancer tissue array

BC12011c each
EUR 186
Description: Bladder cancer tissue array, including TNM, 63 cases/63 cores (core size 1.5mm)

Bladder cancer tissue array

BL2082a each
EUR 546
Description: Bladder cancer tissue array, including TNM, clinical stage and pathology grade, 208 cases/ 208 cores, replacing BL2082

Bladder cancer tissue array

BL2082B each
EUR 546
Description: Bladder cancer tissue array, including TNM and clinical stage, 208 cases/208 cores, replacing BL2082a

Bladder cancer tissue array

BL242 each
EUR 270
Description: Bladder cancer tissue array, with normal tissue, including TNM and pathology grade, 24 cases/48 cores

Stomach cancer tissue array

BS01012e each
EUR 270
Description: Stomach cancer tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition), 72 cases/72 cores, replacing BS01012d

Ovarian cancer tissue array

OV0071a each
EUR 42
Description: Ovarian cancer tissue array, including TNM/Stage (AJCC 8th edition), 7cases/7 cores (core size 1.5mm)

Ovarian cancer tissue array

OV484b each
EUR 270
Description: Ovarian cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/48 cores, replacing OV484a

Ovarian cancer tissue array

OV801b each
EUR 270
Description: Ovarian cancer tissue array, with matched (B7/F7, B8/F8, C3/F3) or unmatched adjacent tissue array, 80 cases/80 cores, replacing OV801

Stomach cancer tissue array

ST484d each
EUR 252
Description: Stomach cancer tissue array, including TNM and pathology grade and HER-2 result, 48 cases/48 cores

Ovarian cancer tissue array

T111a each
EUR 48
Description: Ovarian cancer tissue array, with normal ovary tissue, including TNM and pathology grade, 6 cases/24 cores(1.5mm), replacing T111

Ovarian cancer tissue array

T114a each
EUR 48
Description: Ovarian cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T114

Thyroid cancer tissue array

T152 each
EUR 48
Description: Thyroid cancer tissue array, including TNM and pathology grade, 6 cases/24 cores

Kidney cancer test tissue array (4x (2x3)array)

T074a each
EUR 48
Description: Kidney cancer test tissue array (4x (2x3)array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T074

Colon cancer with cancer adjacent tissue array

T051b each
EUR 48
Description: Colon cancer with cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T051a

Prostate cancer tissue array

BC19021a each
EUR 306
Description: Prostate cancer tissue array, with adjacent tissue and normal tissue, including TNM and pathology grade, 28 cases/72 cores, replacing BC19021

Cervical cancer tissue array

CR1501 each
EUR 258
Description: Cervical cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Lymphoma cancer tissue array

NHL482a each
EUR 222
Description: Lymphoma cancer tissue array, 48 cases/48 cores, replacing NHL482

Prostate cancer tissue array

PR1001 each
EUR 306
Description: Prostate cancer tissue array, including WHO pathology grade and gleason grade, 25 cases/100 cores

Prostate cancer tissue array

PR483d each
EUR 198
Description: Prostate cancer tissue array, including TNM, clinical stage and pathology grade, with Gleason score and WHO grade, 48 cases/48 cores, replacing PR483c

Prostate cancer tissue array

PR484a each
EUR 138
Description: Prostate cancer tissue array, including WHO standerd grade, Gleason grade, Gleason score, TNM and clinical stage, 24 cases/48 cores (core size 1.5mm), replacing PR484

Prostate cancer tissue array

PR633a each
EUR 306
Description: Prostate cancer tissue array, including TNM, clinical stage and pathology grade, 63 cases/63 cores, replacing PR633

Multiple cancer tissue array

MC801 each
EUR 306
Description: Multiple cancer tissue array, replacing BC00012, 80 cases/80 cores, with grade information

Cervical cancer tissue array

T104 each
EUR 48
Description: Cervical cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores

Cerebrum cancer tissue array

T173b each
EUR 66
Description: Cerebrum cancer tissue array, with normal tissue, including pathology grade, 2 serial sections, 6 cases/ 24 cores, replacing T173a

Prostate cancer test tissue array (4x (2x3) array)

T196a each
EUR 66
Description: Prostate cancer test tissue array (4x (2x3) array), including pathology grade, Gleason grade, Gleason score, TNM and clinical stage, 6 cases/24 cores, replacing T196

Endocrine cancer tissue array

EN801b each
EUR 306
Description: Endocrine cancer tissue array, including TNM and clinical stage, 40 cases/80 cores, replacing EN801a

Esophagus cancer tissue array

ES243 each
EUR 270
Description: Esophagus cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Esophagus cancer tissue array

ES781 each
EUR 306
Description: Esophagus cancer tissue array, including pathology grade, TNM and clinical stage, 16 cases/78 cores, replacing BC02111

Colorectal cancer tissue array

BC000110 each
EUR 414
Description: Colorectal cancer tissue array, including pathology grade, TNM and clinical stage, 85 cases/170 cores

Colorectal cancer tissue array

CRM1502 each
EUR 420
Description: Colorectal cancer tissue array, 150 cases/150 cores

Colorectal cancer tissue array

CRM1505 each
EUR 420
Description: Colorectal cancer tissue array, 150 cases/150 cores

Esophageal cancer tissue array

ES481 each
EUR 198
Description: Esophageal cancer tissue array with matched or unmatched normal adjacent tissues (18 cases/48 cores) with stage and grade info

Esophageal cancer tissue array

ES1502 each
EUR 258
Description: Esophageal cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Pancreatic cancer tissue array

PA1001D each
EUR 306
Description: Pancreatic cancer tissue array, with adjacent normal pancreas tissue and normal pancreas tissue, including TNM and pathology grade, 50 cases/100 cores, replacing PA1001c

Pancreatic cancer tissue array

PA2072a each
EUR 546
Description: Pancreatic cancer tissue array, with normal tissue, including TNM and pathology grade, 69 cases/207 cores, replacing PA2072

Pancreatic cancer tissue array

PA501 each
EUR 270
Description: Pancreatic cancer tissue array, including TNM and pathology grade, 50 cases/50 cores (core size 1.5mm)

Pancreatic cancer tissue array

PA807 each
EUR 306
Description: Pancreatic cancer tissue array, with cancer adjaceent tissue and normal tissue as control, including duct adenocarcinoma(PADC), cancer adjaceent pancreatic and normal tissue TNM, clinical stage and pathology grade, 80 cases/ 80 cores(1.5mm)

Pancreatic cancer tissue array

T144a each
EUR 48
Description: Pancreatic cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replacing T144

Endometrium cancer tissue array

BC09012b each
EUR 270
Description: Endometrium cancer tissue array, including pathology grade, TNM and clinical stage(AJCC 8th edition), 63 cases/63 cores, replacing BC09012a

Endometrium cancer tissue array

UT242a each
EUR 270
Description: Endometrium cancer tissue array, with normal tissue, including TNM and pathology grade, 24 cases/24 cores

Endometrium cancer tissue array

UT481 each
EUR 270
Description: Endometrium cancer tissue array, including TNM and pathology grade, 48 cases/48 cores

Endometrium cancer tissue array

UT961 each
EUR 222
Description: Endometrium cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Breast cancer tissue array and normal tissue array

BR726 each
EUR 306
Description: Breast cancer tissue array and normal tissue array, with TNM and grade, 24 cases/72 cores

Lung cancer test tissue array

T046a each
EUR 48
Description: Lung cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T046

Kidney cancer test tissue array

T072b each
EUR 48
Description: Kidney cancer test tissue array, with normal control tissue, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T072a

Breast cancer test tissue array

T086e each
EUR 66
Description: Breast cancer test tissue array, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T086d

Uterus cancer test tissue array

T093 each
EUR 78
Description: Uterus cancer test tissue array, with normal endometrial tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases/24 cores

Testis cancer test tissue array

T233 each
EUR 66
Description: Testis cancer test tissue array, with normal tissue as control, including TNM and clinical stage, 2 serial sections, 6 cases/24 cores

Breast cancer with cancer adjacent breast tissue array

BC081116e each
EUR 306
Description: Breast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type, breast carcinoma with apocrine differentiation and AT tissue,pat hology grade, IHC (ER/PR/Her-2/Ki67) info, TNM/Stage (AJCC 7th edition), 107 cases/110 cores (core size 1.5mm), replacing BC081116d

Cervix cancer tissue array with cancer adjacent tissue

CR501a each
EUR 234
Description: Cervix cancer tissue array with cancer adjacent tissue, including TNM, clinical stage and pathology grade, 50 cases/50 cores, replacing CR501

High-density lung cancer array

LC6161 each
EUR 954
Description: High-density lung cancer array, with stage, grade and normal lung tissue, 322 cases/616 cores

Stomach cancer tissue test array

T011b each
EUR 48
Description: Stomach cancer tissue test array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T011a

Stomach cancer test tissue array

T014a each
EUR 48
Description: Stomach cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores replacing T014

Kidney cancer survey tissue array

KD2085 each
EUR 474
Description: Kidney cancer survey tissue array, no overlapping with KD2089, including TNM, clinical stage and pathology grade, 104 cases/208 cores

Kidney cancer survey tissue array

KD2089 each
EUR 474
Description: Kidney cancer survey tissue array, no overlapping with KD2085, including TNM and pathology grade, 104 cases/208 cores

High-density renal cancer array

KD6161 each
EUR 954
Description: High-density renal cancer array, with stage, grade and normal renal tissue, 322 cases/616 cores

Multiple lung cancer tissue array

LC20813c each
EUR 546
Description: Multiple lung cancer tissue array, including pathology grade, TNM and clinical stage, 192 cases/192 cores, replacing LC120813b

Multiple lung cancer tissue array

LC20815a each
EUR 546
Description: Multiple lung cancer tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma is referenced AJCC 8th version), 208 cases/208 cores, replacing LC20815

Prostate cancer test tissue array

T195d each
EUR 66
Description: Prostate cancer test tissue array, including TNM, Gleason score and pathology grade, 12 cases/24 cores, replaced by T195e

Appendix cancer test tissue array

T413 each
EUR 66
Description: Appendix cancer test tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 6 cases/24 cores

Stomach cancer with matched cancer adjacent tissue array

ST1504 each
EUR 258
Description: Stomach cancer with matched cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 50 cases/150 cores

Prostate cancer tissue array with cancer adjacent tissues

PR721 each
EUR 306
Description: Prostate cancer tissue array with cancer adjacent tissues, including WHO grade, gleason grade, gleason score, TNM and stage info, 24 cases/72 cores

Multiple organ cancer tissue array

BC000111b each
EUR 168
Description: Multiple organ cancer tissue array, including TNM, clinical stage and pathology grade, 39 cases/39 cores, replacing BC000111a

Multiple organ cancer tissue array

BC000119b each
EUR 546
Description: Multiple organ cancer tissue array, including pathology grade, TNM, clinical stage, Gleason grade and Gleason score, 190 cases/190 cores, replacing BC000119a

Multiple organ cancer tissue array

BC000120b each
EUR 546
Description: Multiple organ cancer tissue array, including pathology grade, TNM and clinical stage, 190 cases/190 cores, replacing BC000120a

Uterine cervix cancer tissue array

CR244 each
EUR 66
Description: Uterine cervix cancer tissue array, with adjacent normal tissue, including TNM and pathology grade, 12 cases/24 cores, replacing CR241

Multiple organ cancer tissue array

MC543 each
EUR 354
Description: Multiple organ cancer tissue array, including TNM and pathology grade, 54 cases/ 54 cores

Pancreatic cancer tissue array with cancer adjacent tissue

PA242e each
EUR 66
Description: Pancreatic cancer tissue array with cancer adjacent tissue, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing PA242d

Lung cancer progression tissue array

LC1005b each
EUR 270
Description: Lung cancer progression tissue array, including TNM, clinical stage and pathology grade, 100 cases/100 cores, replacing LC1005a

Liver metastatic cancer tissue array

MLV801 each
EUR 354
Description: Liver metastatic cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores

Lung small cell cancer array and normal lung tissue array

LC10010d each
EUR 306
Description: Lung small cell cancer array and normal lung tissue array, including TNM and clinical stage, 50 cases/100 cores (1.0), replacing LC10010c

Liver cancer antibody screening array

LV1001 each
EUR 306
Description: Liver cancer antibody screening array, including TNM, clinical stage and pathology grade, 25 cases/100 cores

Head and neck cancer tissue array

HN242c each
EUR 66
Description: Head and neck cancer tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing HN242b

Head and neck cancer tissue array

HN602 each
EUR 306
Description: Head and neck cancer tissue array, including pathology grade, TNM and clinical stage (AJCC 8th edition), 60 cases/60 cores

Head & Neck cancer tissue array

T343 each
EUR 66
Description: Head & Neck cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replaced by T343a

Head & Neck cancer tissue array

T343a each
EUR 66
Description: Head & Neck cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replacing T343

Lung cancer with matched cancer adjacent lung tissue array

LC481 each
EUR 168
Description: Lung cancer with matched cancer adjacent lung tissue array, including pathology grade, TNM and clinical stage, 12 cases/48 cores

Lung cancer with lung tissue array

LC1503 each
EUR 258
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma fererence AJCC 8th edition), 75 cases/150 cores, replacing LUC1503

Lung cancer with lung tissue array

LC483a each
EUR 168
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma reference AJCC 8th version), 48 cases/48 cores, replacing LC483

Lung cancer with lung tissue array

LC8010 each
EUR 270
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma reference AJCC 8th edition), 80 cases/80 cores, replacing LC801

Lung cancer with lung tissue array

T043b each
EUR 66
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T043a

Liver cancer with matched cancer adjacent liver tissue array

LV1505a each
EUR 258
Description: Liver cancer with matched cancer adjacent liver tissue array, including pathology grade, TNM and clinical stage, replacing LV1505

Liver cancer and liver tissue array

BC03116a each
EUR 306
Description: Liver cancer and liver tissue array, including pathology grade, TNM and clinical stage, 70 cases/70 cores, replacing BC03116

Lung small cell cancer tissue array

LC703a each
EUR 270
Description: Lung small cell cancer tissue array, including pathology TNM and clinical stage, 44 cases/44 cores, replacing LC703.

Lung cancer and normal tissue array

LC722 each
EUR 306
Description: Lung cancer and normal tissue array, with TNM and grade data, 24 cases/72 cores

Skin cancer and normal tissue array

SK721 each
EUR 306
Description: Skin cancer and normal tissue array, with stage and grade info, 24 cases/72 cores

Colon cancer tissue array with matched cancer adjacent tissue

BC05023a each
EUR 270
Description: Colon cancer tissue array with matched cancer adjacent tissue, including TNM and pathology grade, 18 cases/ 54 cores, replacing BC05023

Colon cancer tissue array with matched cancer adjacent tissue

CO801b each
EUR 270
Description: Colon cancer tissue array with matched cancer adjacent tissue, including pathology grade, TNM and clinical stage, 40 cases/80 cores, replcing CO801a

Lung cancer tissue array (1 of 5)

LC20812a each
EUR 546
Description: Lung cancer tissue array (1 of 5), with normal tissue, including TNM and pathology grade, 208 cases/208 cores replacing LC20812

Lung cancer tissue array (2 of 5)

LC20813 each
EUR 546
Description: Lung cancer tissue array (2 of 5), including TNM and pathology grade, 208 cases/208 cores, replaced by LC20813b

Lung cancer tissue array (4 of 5)

LC20815 each
EUR 546
Description: Lung cancer tissue array (4 of 5), including TNM and pathology grade, 208 cases/208 cores, replaced by LC20815a

Lung cancer tissue array (5 of 5)

LC20816 each
EUR 546
Description: Lung cancer tissue array (5 of 5), including TNM and pathology grade, 208 cases/208 cores

Lung cancer tissue array (5 of 5)

LC20816a each
EUR 546
Description: Lung cancer tissue array (5 of 5), including TNM and pathology grade, 208 cases/208 cores (cores size 1.0mm),replacing LC20816

Liver cancer and normal tissue array

BC03116b each
EUR 306
Description: Liver cancer and normal tissue array, including pathology grade, TNM and clinical stage, 70 cases/70 cores, replacing BC03116a

Colon cancer and normal tissue array

BC051111 each
EUR 546
Description: Colon cancer and normal tissue array, including TNM, clinical stage and pathology grade, 100 cases/200 cores

Colon cancer with colon tissue array

CO1021a each
EUR 306
Description: Colon cancer with colon tissue array, including pathology grade, with MMR (MLH1/PMS2/MSH2/MSH6) IHC results,TNM and clinical stage, containing 86 cases of adenocarcinoma, 4 papillary adenocarcinoma, 7 mucinous adenocarcinoma, 2 adenoma, 1 congenital megacolon, 2 colon tissue, 102 cases/102 cores replacing CO1021

Colon cancer with colon tissue array

CO1921 each
EUR 546
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 192 cases/192 cores

Colon cancer with colon tissue array

CO2161b each
EUR 474
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 216 cases/216 cores, replacing CO2161a

Colon cancer with colon tissue array

CO721 each
EUR 270
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 24 cases/72 cores

Colon cancer with colon tissue array

CO805 each
EUR 258
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 40 cases/80 cores

Liver cancer with liver tissue array

LV1021a each
EUR 204
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 102 cases/102 cores, replacing LV1021

Liver cancer with liver tissue array

LV243 each
EUR 66
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores

Liver cancer with liver tissue array

LV722 each
EUR 306
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 24 cases/72 cores, replacing LV721

Liver cancer and normal tissue array

LV8010 each
EUR 306
Description: Liver cancer and normal tissue array, with stage and grade info, 80 cases/80 cores, replacing BC03011

Schwann cell culture model suggests that miR-150-5p is a strong negative regulator of genes CREB, BDNF and NGF. Identification of deregulated miRNAs may help in understanding the complex underlying pathomechamism ATTRv development and related multisystemic pathology. Further investigation is needed on the role of circulating miR-150-5p to predict shifts TTRv operator of asymptomatic status appearance of symptoms.