Circulating MicroRNA Expression Profiles in Patients with Stable and Unstable Angina
Objective: High incidence of and deaths from unstable angina (UA) is, for the most part, a consequence of the lack of highly sensitive and specific non-invasive markers. Circulating microRNAs (miRNAs) have been widely recommended as potential biomarkers for various diseases. In this study, we characterized the typical miRNA expression profile in patients with stable angina (SA), UA, and normal coronary arteries (NCA), and identify promising candidates for the diagnosis of UA.
Methods: Serum collected from patients with SA, UA, and NCA who visited the Department of Cardiovascular Diseases Meizhou People’s Hospital. Small RNA sequencing performed on the Illumina HiSeq 2500 platform. MiRNA expression in different groups of patients profiled and then confirmed by that in an independent set of patients. The function of miRNAs are expressed differently allegedly using gene ontology classification and Kyoto Encyclopedia of Genes and Genomes pathway analysis.
Results: Our results suggest that circulating miRNA expression profiles differ between SA, UA, and patient NCA. A total of 36 and 161 miRNAs are dysregulated in SA and UA patients, respectively. validated miRNA
expression by reverse transcription quantitative polymerase chain reaction.
Conclusion: The results showed that circulating miRNAs are potential biomarkers UA. There is a positive correlation between birth weight and BMI pregestational pregnant individuals (r = 0.48, P <0.001). One hundred and eight miRNAs were differentially expressed between normal and overweight / obese group, which target genes are enriched in the metabolic pathways.
C19MC five miRNAs (miR-516a-5p, miR-516b-5p, miR-520A-3p, miR-1323, mir-523-5p) were upregulated in overweight / obese group. Target enrichment analysis indicates their involvement in the post-embryonic development, lipid and glucose homeostasis, differentiation of T cells and the development of the nervous system.
Circulating microRNAs profile variant transthyretin amyloidosis patients
Variant transthyretin amyloidosis (ATTRv) is a rare autosomal dominant disease characterized by the accumulation of amyloid in many organs, most cause sensory-motor neuropathy, cardiomyopathy, and dysautonomia. The purpose of this study was to report the profiles of microRNAs (miRNAs) expression ATTRv identified in patients’ blood.
ATTRv ten patients, 10 asymptomatic carriers of the variant transthyretin (TTRv), 10 patients with Charcot-Marie-Tooth disease (CMT), and 10 healthy controls were studied. Human Schwann cell cultures were used to study the regulation of miR-150-5p effect on the expression of cAMP response element-binding protein (CREB), brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF).
ATTRv patients had 33 miRNAs up-regulated and 48 down-regulated compared to healthy controls; 9 miRNAs up-and-regulated and 30 down-regulated compared CMT patients; 19 miRNAs up-and-regulated and 38 down-regulated compared TTRv asymptomatic carriers. Twelve of the 19 miRNAs upregulated have fold higher than 100. The validation study showed miR-150-5p as a valuable biomarker for patients ATTRv TTRv distinguish from asymptomatic carriers (AUC: 0.9728; p <0.0001).
Rat SeraMir Exosome RNA 384 microRNA qPCR Profiler Assay Set |
|||
RA812A-1 | SBI | 20 profiles | EUR 469 |
Colon cancer test tissue array (4x (2x3) array) |
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T055a | TissueArray | each | EUR 48 |
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055 |
Colon cancer test tissue array (4x (2x3) array) |
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T055b | TissueArray | each | EUR 48 |
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055a |
Kidney cancer test tissue array (4x (2x3)array) |
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T074a | TissueArray | each | EUR 48 |
Description: Kidney cancer test tissue array (4x (2x3)array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T074 |
Lung cancer tissue array |
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VLC11 | TissueArray | each | EUR 66 |
Description: Lung cancer tissue array, with TNM and grade info, 11 cases/11 cores |
Lung cancer tissue array |
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VLC12b | TissueArray | each | EUR 66 |
Description: Lung cancer tissue array, including pathology grade, TNM and clinical stage, 12 cases/12 cores, replacing VLC12a |
Lung cancer tissue array |
|||
LC1261 | TissueArray | each | EUR 354 |
Description: Lung cancer tissue array, including pathology grade, TNM, clinical stage and PD-L1 (Sp263) information, 63 cases/126 cores |
Lung cancer tissue array |
|||
LC243 | TissueArray | each | EUR 198 |
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores |
Lung cancer tissue array |
|||
LC485 | TissueArray | each | EUR 198 |
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores |
Lung cancer tissue array |
|||
LC721 | TissueArray | each | EUR 270 |
Description: Lung cancer tissue array, including TNM and pathology grade, 24 cases/72 cores |
Lung cancer tissue array |
|||
LC726b | TissueArray | each | EUR 222 |
Description: Lung cancer tissue array, including TNM, clinical stage and pathology grade, 72 cases/72 cores, replacing LC726 |
Lung cancer tissue array |
|||
LUN703 | TissueArray | each | EUR 198 |
Description: Lung cancer tissue array,including pathology grade and TNM,7 cases/70 cores (core size 1.5mm) |
Lung cancer tissue array |
|||
NSC151 | TissueArray | each | EUR 420 |
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores |
Lung cancer tissue array |
|||
NSC153 | TissueArray | each | EUR 420 |
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores |
Lung cancer tissue array |
|||
NSC154 | TissueArray | each | EUR 420 |
Description: Lung cancer tissue array, with ALK results,, 150 cases/150 cores |
Lung cancer tissue array |
|||
NSC155 | TissueArray | each | EUR 420 |
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores |
Lung cancer tissue array |
|||
NSC156 | TissueArray | each | EUR 420 |
Description: Lung cancer tissue array, 150 cases/150 cores |
Lung cancer tissue array |
|||
NSC157 | TissueArray | each | EUR 420 |
Description: Lung cancer tissue array, 150 cases/150 cores |
Prostate cancer test tissue array (4x (2x3) array) |
|||
T196a | TissueArray | each | EUR 66 |
Description: Prostate cancer test tissue array (4x (2x3) array), including pathology grade, Gleason grade, Gleason score, TNM and clinical stage, 6 cases/24 cores, replacing T196 |
Colon cancer tissue array |
|||
CO1502 | TissueArray | each | EUR 258 |
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores |
Colon cancer tissue array |
|||
CRM1503 | TissueArray | each | EUR 420 |
Description: Colon cancer tissue array, 150 cases/150 cores |
Colon cancer tissue array |
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CRM1504 | TissueArray | each | EUR 420 |
Description: Colon cancer tissue array, 150 cases/150 cores |
Colon cancer tissue array |
|||
CRM1506 | TissueArray | each | EUR 420 |
Description: Colon cancer tissue array, 150 cases/150 cores |
Colon cancer tissue array |
|||
CRM1507 | TissueArray | each | EUR 420 |
Description: Colon cancer tissue array, 150 cases/150 cores |
Colon cancer tissue array |
|||
CO1503 | TissueArray | each | EUR 258 |
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores |
Colon cancer tissue array |
|||
CO244 | TissueArray | each | EUR 270 |
Description: Colon cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores |
Colon cancer tissue array |
|||
CO485 | TissueArray | each | EUR 270 |
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/48 cores |
Colon cancer tissue array |
|||
CO486a | TissueArray | each | EUR 414 |
Description: Colon cancer tissue array, including pathology grade, TNM and clinical stage, 2 serial sections, 48 cases/96 cores, replacing CO486 |
Colon cancer tissue array |
|||
CO641 | TissueArray | each | EUR 258 |
Description: Colon cancer tissue array, including TNM, stage and pathology grade, 64 cases/ 64 cores |
Colon cancer tissue array |
|||
CO804b | TissueArray | each | EUR 270 |
Description: Colon cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores, replcing CO804a |
Colon cancer tissue array |
|||
CO901a | TissueArray | each | EUR 306 |
Description: Colon cancer tissue array, with adjacent normal colon tissue, including TNM, clinical stage and pathology grade, 50 cases/90 cores, replacing CO901 |
Colon cancer tissue array |
|||
CO961 | TissueArray | each | EUR 258 |
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores |
Colon cancer tissue array |
|||
CO962 | TissueArray | each | EUR 258 |
Description: Colon cancer tissue array, including pathology grade, TNM/Stage, 48 cases/96 cores |
Liver cancer tissue array |
|||
LV1002 | TissueArray | each | EUR 306 |
Description: Liver cancer tissue array, including TNM, clinical stage and pathology grade, 50 cases/100 cores |
Liver cancer tissue array |
|||
LV1502 | TissueArray | each | EUR 258 |
Description: Liver cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores |
Liver cancer tissue array |
|||
LV2161 | TissueArray | each | EUR 546 |
Description: Liver cancer tissue array, with normal tissue, including TNM and pathology grade, 216 cases/216 cores |
Liver cancer tissue array |
|||
LV245 | TissueArray | each | EUR 198 |
Description: Liver cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores |
Liver cancer tissue array |
|||
T031c | TissueArray | each | EUR 66 |
Description: Liver cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24cores(1,5mm), replacing T031b |
Vulva cancer tissue array |
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UV241a | TissueArray | each | EUR 66 |
Description: Vulva cancer tissue array, including TNM, clinical stage and pathology diagnosis, replacing UV241 |
Colon cancer and lung cancer tissue array |
|||
CLC601 | TissueArray | each | EUR 306 |
Description: Colon cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores |
Kidney cancer tissue array |
|||
BC07014b | TissueArray | each | EUR 168 |
Description: Kidney cancer tissue array, including pathology grade, TNM and clinical stage, 72 cases/72 cores, replacing BC07014a |
Breast cancer tissue array |
|||
BR042b | TissueArray | each | EUR 78 |
Description: Breast cancer tissue array, including TNM and pathology grade, 4 cases/4 cores, replacing BR042a |
Breast cancer tissue array |
|||
BR1006a | TissueArray | each | EUR 306 |
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 50 cases/100 cores (core size 1.0mm), replacing BR1006 |
Breast cancer tissue array |
|||
BR1141a | TissueArray | each | EUR 354 |
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, IHC marker (ER, PR, HER2 and Ki-67), 114 cases/114 cores, replacing BR1141 |
Breast cancer tissue array |
|||
BR1401 | TissueArray | each | EUR 414 |
Description: Breast cancer tissue array, including TNM and pathology grade, IHC markers ER/PR/Her-2 results, 140 cases/140 cores (core size 1.0mm) |
Breast cancer tissue array |
|||
BR1503f | TissueArray | each | EUR 306 |
Description: Breast cancer tissue array, including TNM and pathology grade, with IHC results of Her-2\ER\PR\Ki67, 75 cases/ 150 cores, replacing BR1503e |
Breast cancer tissue array |
|||
BR1505e | TissueArray | each | EUR 306 |
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage, and IHC(HER2/ER/PR/Ki67), 75 cases/150 cores, replacing BR1505d |
Breast cancer tissue array |
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BR2161 | TissueArray | each | EUR 546 |
Description: Breast cancer tissue array, including TNM and pathology grade, 216 cases/216 cores |
Breast cancer tissue array |
|||
BR247a | TissueArray | each | EUR 234 |
Description: Breast cancer tissue array, with normal tissue, including TNM and pathology grade, IHC marker (HER2), 24 cases/48 cores replacing BR247 |
Breast cancer tissue array |
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BR488 | TissueArray | each | EUR 306 |
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage (AJCC 7th edition), and IHC marker(ER,PR,Her-2), 48 cases/48 cores |
Breast cancer tissue array |
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BR501 | TissueArray | each | EUR 270 |
Description: Breast cancer tissue array, including TNM and pathology grade, 50 cases/ 50 cores (core size 1.5mm) |
Breast cancer tissue array |
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BR8015a | TissueArray | each | EUR 306 |
Description: Breast cancer tissue array, with adjacent normal tissue and normal tissue, including TNM and pathology grade, 80 cases/80 cores, replacing BC08014 |
Breast cancer tissue array |
|||
BR964 | TissueArray | each | EUR 222 |
Description: Breast cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores |
Kidney cancer tissue array |
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KD245 | TissueArray | each | EUR 66 |
Description: Kidney cancer tissue array, including TNM, clinical stage and pathology grade, 24 cases/ 24 cores |
Kidney cancer tissue array |
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KD485 | TissueArray | each | EUR 168 |
Description: Kidney cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores |
Rectum cancer tissue array |
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RE1503 | TissueArray | each | EUR 258 |
Description: Rectum cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores |
Cervix cancer tissue array |
|||
T104a | TissueArray | each | EUR 48 |
Description: Cervix cancer tissue array, including squamous cell carcinoma, glassy cell carcinoma and adenocarcinoma, pathology grade, TNM and clinical stage, 6 cases/24 cores (1.5mm), replacing T104 |
Breast cancer tissue array |
|||
T089c | TissueArray | each | EUR 48 |
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores(1.5mm), replacing T089b |
Bladder cancer tissue array |
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BC12011c | TissueArray | each | EUR 186 |
Description: Bladder cancer tissue array, including TNM, 63 cases/63 cores (core size 1.5mm) |
Bladder cancer tissue array |
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BL2082a | TissueArray | each | EUR 546 |
Description: Bladder cancer tissue array, including TNM, clinical stage and pathology grade, 208 cases/ 208 cores, replacing BL2082 |
Bladder cancer tissue array |
|||
BL2082B | TissueArray | each | EUR 546 |
Description: Bladder cancer tissue array, including TNM and clinical stage, 208 cases/208 cores, replacing BL2082a |
Bladder cancer tissue array |
|||
BL242 | TissueArray | each | EUR 270 |
Description: Bladder cancer tissue array, with normal tissue, including TNM and pathology grade, 24 cases/48 cores |
Stomach cancer tissue array |
|||
BS01012e | TissueArray | each | EUR 270 |
Description: Stomach cancer tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition), 72 cases/72 cores, replacing BS01012d |
Ovarian cancer tissue array |
|||
OV0071a | TissueArray | each | EUR 42 |
Description: Ovarian cancer tissue array, including TNM/Stage (AJCC 8th edition), 7cases/7 cores (core size 1.5mm) |
Ovarian cancer tissue array |
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OV484b | TissueArray | each | EUR 270 |
Description: Ovarian cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/48 cores, replacing OV484a |
Ovarian cancer tissue array |
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OV801b | TissueArray | each | EUR 270 |
Description: Ovarian cancer tissue array, with matched (B7/F7, B8/F8, C3/F3) or unmatched adjacent tissue array, 80 cases/80 cores, replacing OV801 |
Ovarian cancer tissue array |
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T111a | TissueArray | each | EUR 48 |
Description: Ovarian cancer tissue array, with normal ovary tissue, including TNM and pathology grade, 6 cases/24 cores(1.5mm), replacing T111 |
Ovarian cancer tissue array |
|||
T114a | TissueArray | each | EUR 48 |
Description: Ovarian cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T114 |
Thyroid cancer tissue array |
|||
T152 | TissueArray | each | EUR 48 |
Description: Thyroid cancer tissue array, including TNM and pathology grade, 6 cases/24 cores |
Stomach cancer tissue array |
|||
ST484d | TissueArray | each | EUR 252 |
Description: Stomach cancer tissue array, including TNM and pathology grade and HER-2 result, 48 cases/48 cores |
Mouse SeraMir Exosome RNA 384 microRNA qPCR Profiler Assay Set (20 assays) |
|||
RA811A-1 | SBI | 20 profiles | EUR 469 |
Stomach cancer and lung cancer tissue array |
|||
SLC601 | TissueArray | each | EUR 306 |
Description: Stomach cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores |
Breast cancer tissue array and normal tissue array |
|||
BR726 | TissueArray | each | EUR 306 |
Description: Breast cancer tissue array and normal tissue array, with TNM and grade, 24 cases/72 cores |
Prostate cancer tissue array |
|||
BC19021a | TissueArray | each | EUR 306 |
Description: Prostate cancer tissue array, with adjacent tissue and normal tissue, including TNM and pathology grade, 28 cases/72 cores, replacing BC19021 |
Cervical cancer tissue array |
|||
CR1501 | TissueArray | each | EUR 258 |
Description: Cervical cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores |
Cerebrum cancer tissue array |
|||
T173b | TissueArray | each | EUR 66 |
Description: Cerebrum cancer tissue array, with normal tissue, including pathology grade, 2 serial sections, 6 cases/ 24 cores, replacing T173a |
Prostate cancer tissue array |
|||
PR1001 | TissueArray | each | EUR 306 |
Description: Prostate cancer tissue array, including WHO pathology grade and gleason grade, 25 cases/100 cores |
Prostate cancer tissue array |
|||
PR483d | TissueArray | each | EUR 198 |
Description: Prostate cancer tissue array, including TNM, clinical stage and pathology grade, with Gleason score and WHO grade, 48 cases/48 cores, replacing PR483c |
Prostate cancer tissue array |
|||
PR484a | TissueArray | each | EUR 138 |
Description: Prostate cancer tissue array, including WHO standerd grade, Gleason grade, Gleason score, TNM and clinical stage, 24 cases/48 cores (core size 1.5mm), replacing PR484 |
Prostate cancer tissue array |
|||
PR633a | TissueArray | each | EUR 306 |
Description: Prostate cancer tissue array, including TNM, clinical stage and pathology grade, 63 cases/63 cores, replacing PR633 |
Lymphoma cancer tissue array |
|||
NHL482a | TissueArray | each | EUR 222 |
Description: Lymphoma cancer tissue array, 48 cases/48 cores, replacing NHL482 |
Multiple cancer tissue array |
|||
MC801 | TissueArray | each | EUR 306 |
Description: Multiple cancer tissue array, replacing BC00012, 80 cases/80 cores, with grade information |
Cervical cancer tissue array |
|||
T104 | TissueArray | each | EUR 48 |
Description: Cervical cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores |
Esophagus cancer tissue array |
|||
ES243 | TissueArray | each | EUR 270 |
Description: Esophagus cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores |
Esophagus cancer tissue array |
|||
ES781 | TissueArray | each | EUR 306 |
Description: Esophagus cancer tissue array, including pathology grade, TNM and clinical stage, 16 cases/78 cores, replacing BC02111 |
Endocrine cancer tissue array |
|||
EN801b | TissueArray | each | EUR 306 |
Description: Endocrine cancer tissue array, including TNM and clinical stage, 40 cases/80 cores, replacing EN801a |
Colon cancer with cancer adjacent tissue array |
|||
T051b | TissueArray | each | EUR 48 |
Description: Colon cancer with cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T051a |
Colorectal cancer tissue array |
|||
BC000110 | TissueArray | each | EUR 414 |
Description: Colorectal cancer tissue array, including pathology grade, TNM and clinical stage, 85 cases/170 cores |
Colorectal cancer tissue array |
|||
CRM1502 | TissueArray | each | EUR 420 |
Description: Colorectal cancer tissue array, 150 cases/150 cores |
Colorectal cancer tissue array |
|||
CRM1505 | TissueArray | each | EUR 420 |
Description: Colorectal cancer tissue array, 150 cases/150 cores |
Pancreatic cancer tissue array |
|||
T144a | TissueArray | each | EUR 48 |
Description: Pancreatic cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replacing T144 |
Esophageal cancer tissue array |
|||
ES1502 | TissueArray | each | EUR 258 |
Description: Esophageal cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores |
Pancreatic cancer tissue array |
|||
PA1001D | TissueArray | each | EUR 306 |
Description: Pancreatic cancer tissue array, with adjacent normal pancreas tissue and normal pancreas tissue, including TNM and pathology grade, 50 cases/100 cores, replacing PA1001c |
Pancreatic cancer tissue array |
|||
PA2072a | TissueArray | each | EUR 546 |
Description: Pancreatic cancer tissue array, with normal tissue, including TNM and pathology grade, 69 cases/207 cores, replacing PA2072 |
Pancreatic cancer tissue array |
|||
PA501 | TissueArray | each | EUR 270 |
Description: Pancreatic cancer tissue array, including TNM and pathology grade, 50 cases/50 cores (core size 1.5mm) |
Pancreatic cancer tissue array |
|||
PA807 | TissueArray | each | EUR 306 |
Description: Pancreatic cancer tissue array, with cancer adjaceent tissue and normal tissue as control, including duct adenocarcinoma(PADC), cancer adjaceent pancreatic and normal tissue TNM, clinical stage and pathology grade, 80 cases/ 80 cores(1.5mm) |
Endometrium cancer tissue array |
|||
BC09012b | TissueArray | each | EUR 270 |
Description: Endometrium cancer tissue array, including pathology grade, TNM and clinical stage(AJCC 8th edition), 63 cases/63 cores, replacing BC09012a |
Endometrium cancer tissue array |
|||
UT242a | TissueArray | each | EUR 270 |
Description: Endometrium cancer tissue array, with normal tissue, including TNM and pathology grade, 24 cases/24 cores |
Endometrium cancer tissue array |
|||
UT481 | TissueArray | each | EUR 270 |
Description: Endometrium cancer tissue array, including TNM and pathology grade, 48 cases/48 cores |
Endometrium cancer tissue array |
|||
UT961 | TissueArray | each | EUR 222 |
Description: Endometrium cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores |
LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles |
|||
RA900A-1 | SBI | 20 profiles | EUR 1020 |
Lung cancer test tissue array |
|||
T046a | TissueArray | each | EUR 48 |
Description: Lung cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T046 |
Uterus cancer test tissue array |
|||
T093 | TissueArray | each | EUR 78 |
Description: Uterus cancer test tissue array, with normal endometrial tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases/24 cores |
Testis cancer test tissue array |
|||
T233 | TissueArray | each | EUR 66 |
Description: Testis cancer test tissue array, with normal tissue as control, including TNM and clinical stage, 2 serial sections, 6 cases/24 cores |
Kidney cancer test tissue array |
|||
T072b | TissueArray | each | EUR 48 |
Description: Kidney cancer test tissue array, with normal control tissue, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T072a |
Breast cancer test tissue array |
|||
T086e | TissueArray | each | EUR 66 |
Description: Breast cancer test tissue array, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T086d |
High-density lung cancer array |
|||
LC6161 | TissueArray | each | EUR 954 |
Description: High-density lung cancer array, with stage, grade and normal lung tissue, 322 cases/616 cores |
Stomach cancer tissue test array |
|||
T011b | TissueArray | each | EUR 48 |
Description: Stomach cancer tissue test array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T011a |
Stomach cancer test tissue array |
|||
T014a | TissueArray | each | EUR 48 |
Description: Stomach cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores replacing T014 |
Mouse LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles |
|||
RA930A-1 | SBI | 20 profiles | EUR 1020 |
Lung small cell cancer array and normal lung tissue array |
|||
LC10010d | TissueArray | each | EUR 306 |
Description: Lung small cell cancer array and normal lung tissue array, including TNM and clinical stage, 50 cases/100 cores (1.0), replacing LC10010c |
Kidney cancer survey tissue array |
|||
KD2085 | TissueArray | each | EUR 474 |
Description: Kidney cancer survey tissue array, no overlapping with KD2089, including TNM, clinical stage and pathology grade, 104 cases/208 cores |
Kidney cancer survey tissue array |
|||
KD2089 | TissueArray | each | EUR 474 |
Description: Kidney cancer survey tissue array, no overlapping with KD2085, including TNM and pathology grade, 104 cases/208 cores |
High-density renal cancer array |
|||
KD6161 | TissueArray | each | EUR 954 |
Description: High-density renal cancer array, with stage, grade and normal renal tissue, 322 cases/616 cores |
Multiple lung cancer tissue array |
|||
LC20813c | TissueArray | each | EUR 546 |
Description: Multiple lung cancer tissue array, including pathology grade, TNM and clinical stage, 192 cases/192 cores, replacing LC120813b |
Multiple lung cancer tissue array |
|||
LC20815a | TissueArray | each | EUR 546 |
Description: Multiple lung cancer tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma is referenced AJCC 8th version), 208 cases/208 cores, replacing LC20815 |
Prostate cancer test tissue array |
|||
T195d | TissueArray | each | EUR 66 |
Description: Prostate cancer test tissue array, including TNM, Gleason score and pathology grade, 12 cases/24 cores, replaced by T195e |
Appendix cancer test tissue array |
|||
T413 | TissueArray | each | EUR 66 |
Description: Appendix cancer test tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 6 cases/24 cores |
Breast cancer with cancer adjacent breast tissue array |
|||
BC081116e | TissueArray | each | EUR 306 |
Description: Breast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type, breast carcinoma with apocrine differentiation and AT tissue,pat hology grade, IHC (ER/PR/Her-2/Ki67) info, TNM/Stage (AJCC 7th edition), 107 cases/110 cores (core size 1.5mm), replacing BC081116d |
Cervix cancer tissue array with cancer adjacent tissue |
|||
CR501a | TissueArray | each | EUR 234 |
Description: Cervix cancer tissue array with cancer adjacent tissue, including TNM, clinical stage and pathology grade, 50 cases/50 cores, replacing CR501 |
Multiple organ cancer tissue array |
|||
BC000111b | TissueArray | each | EUR 168 |
Description: Multiple organ cancer tissue array, including TNM, clinical stage and pathology grade, 39 cases/39 cores, replacing BC000111a |
Multiple organ cancer tissue array |
|||
BC000119b | TissueArray | each | EUR 546 |
Description: Multiple organ cancer tissue array, including pathology grade, TNM, clinical stage, Gleason grade and Gleason score, 190 cases/190 cores, replacing BC000119a |
Multiple organ cancer tissue array |
|||
BC000120b | TissueArray | each | EUR 546 |
Description: Multiple organ cancer tissue array, including pathology grade, TNM and clinical stage, 190 cases/190 cores, replacing BC000120a |
Uterine cervix cancer tissue array |
|||
CR244 | TissueArray | each | EUR 66 |
Description: Uterine cervix cancer tissue array, with adjacent normal tissue, including TNM and pathology grade, 12 cases/24 cores, replacing CR241 |
Multiple organ cancer tissue array |
|||
MC543 | TissueArray | each | EUR 354 |
Description: Multiple organ cancer tissue array, including TNM and pathology grade, 54 cases/ 54 cores |
Stomach cancer with matched cancer adjacent tissue array |
|||
ST1504 | TissueArray | each | EUR 258 |
Description: Stomach cancer with matched cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 50 cases/150 cores |
Prostate cancer tissue array with cancer adjacent tissues |
|||
PR721 | TissueArray | each | EUR 306 |
Description: Prostate cancer tissue array with cancer adjacent tissues, including WHO grade, gleason grade, gleason score, TNM and stage info, 24 cases/72 cores |
Lung cancer progression tissue array |
|||
LC1005b | TissueArray | each | EUR 270 |
Description: Lung cancer progression tissue array, including TNM, clinical stage and pathology grade, 100 cases/100 cores, replacing LC1005a |
Liver metastatic cancer tissue array |
|||
MLV801 | TissueArray | each | EUR 354 |
Description: Liver metastatic cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores |
Pancreatic cancer tissue array with cancer adjacent tissue |
|||
PA242e | TissueArray | each | EUR 66 |
Description: Pancreatic cancer tissue array with cancer adjacent tissue, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing PA242d |
Liver cancer antibody screening array |
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LV1001 | TissueArray | each | EUR 306 |
Description: Liver cancer antibody screening array, including TNM, clinical stage and pathology grade, 25 cases/100 cores |
Head and neck cancer tissue array |
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HN242c | TissueArray | each | EUR 66 |
Description: Head and neck cancer tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing HN242b |
Head and neck cancer tissue array |
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HN602 | TissueArray | each | EUR 306 |
Description: Head and neck cancer tissue array, including pathology grade, TNM and clinical stage (AJCC 8th edition), 60 cases/60 cores |
Head & Neck cancer tissue array |
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T343 | TissueArray | each | EUR 66 |
Description: Head & Neck cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replaced by T343a |
Head & Neck cancer tissue array |
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T343a | TissueArray | each | EUR 66 |
Description: Head & Neck cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replacing T343 |
Lung cancer with lung tissue array |
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LC1503 | TissueArray | each | EUR 258 |
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma fererence AJCC 8th edition), 75 cases/150 cores, replacing LUC1503 |
Lung cancer with lung tissue array |
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LC483a | TissueArray | each | EUR 168 |
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma reference AJCC 8th version), 48 cases/48 cores, replacing LC483 |
Lung cancer with lung tissue array |
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LC8010 | TissueArray | each | EUR 270 |
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma reference AJCC 8th edition), 80 cases/80 cores, replacing LC801 |
Lung cancer with lung tissue array |
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T043b | TissueArray | each | EUR 66 |
Description: Lung cancer with lung tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T043a |
Lung cancer with matched cancer adjacent lung tissue array |
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LC481 | TissueArray | each | EUR 168 |
Description: Lung cancer with matched cancer adjacent lung tissue array, including pathology grade, TNM and clinical stage, 12 cases/48 cores |
Liver cancer and liver tissue array |
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BC03116a | TissueArray | each | EUR 306 |
Description: Liver cancer and liver tissue array, including pathology grade, TNM and clinical stage, 70 cases/70 cores, replacing BC03116 |
Lung small cell cancer tissue array |
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LC703a | TissueArray | each | EUR 270 |
Description: Lung small cell cancer tissue array, including pathology TNM and clinical stage, 44 cases/44 cores, replacing LC703. |
Lung cancer and normal tissue array |
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LC722 | TissueArray | each | EUR 306 |
Description: Lung cancer and normal tissue array, with TNM and grade data, 24 cases/72 cores |
Skin cancer and normal tissue array |
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SK721 | TissueArray | each | EUR 306 |
Description: Skin cancer and normal tissue array, with stage and grade info, 24 cases/72 cores |
Metastatic esophageal cancer tissue array |
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ES806 | TissueArray | each | EUR 306 |
Description: Metastatic esophageal cancer tissue array, 40 cases/80 cores |
Liver cancer with matched cancer adjacent liver tissue array |
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LV1505a | TissueArray | each | EUR 258 |
Description: Liver cancer with matched cancer adjacent liver tissue array, including pathology grade, TNM and clinical stage, replacing LV1505 |
Esophageal cancer progression tissue array |
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ES804 | TissueArray | each | EUR 270 |
Description: Esophageal cancer progression tissue array, 76 cases/80 cores |
Liver cancer and normal tissue array |
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BC03116b | TissueArray | each | EUR 306 |
Description: Liver cancer and normal tissue array, including pathology grade, TNM and clinical stage, 70 cases/70 cores, replacing BC03116a |
Colon cancer and normal tissue array |
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BC051111 | TissueArray | each | EUR 546 |
Description: Colon cancer and normal tissue array, including TNM, clinical stage and pathology grade, 100 cases/200 cores |
Colon cancer with colon tissue array |
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CO1021a | TissueArray | each | EUR 306 |
Description: Colon cancer with colon tissue array, including pathology grade, with MMR (MLH1/PMS2/MSH2/MSH6) IHC results,TNM and clinical stage, containing 86 cases of adenocarcinoma, 4 papillary adenocarcinoma, 7 mucinous adenocarcinoma, 2 adenoma, 1 congenital megacolon, 2 colon tissue, 102 cases/102 cores replacing CO1021 |
Colon cancer with colon tissue array |
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CO1921 | TissueArray | each | EUR 546 |
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 192 cases/192 cores |
Colon cancer with colon tissue array |
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CO2161b | TissueArray | each | EUR 474 |
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 216 cases/216 cores, replacing CO2161a |
Colon cancer with colon tissue array |
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CO721 | TissueArray | each | EUR 270 |
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 24 cases/72 cores |
Colon cancer with colon tissue array |
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CO805 | TissueArray | each | EUR 258 |
Description: Colon cancer with colon tissue array, including pathology grade, TNM and clinical stage, 40 cases/80 cores |
Liver cancer with liver tissue array |
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LV722 | TissueArray | each | EUR 306 |
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 24 cases/72 cores, replacing LV721 |
Brain cancer and normal tissue array |
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GL1001a | TissueArray | each | EUR 306 |
Description: Brain cancer and normal tissue array, including pathology grade, 100 cases/100 cores, replacing GL1001 |
Liver cancer with liver tissue array |
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LV1021a | TissueArray | each | EUR 204 |
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 102 cases/102 cores, replacing LV1021 |
Liver cancer with liver tissue array |
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LV243 | TissueArray | each | EUR 66 |
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores |
Liver cancer and normal tissue array |
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LV8010 | TissueArray | each | EUR 306 |
Description: Liver cancer and normal tissue array, with stage and grade info, 80 cases/80 cores, replacing BC03011 |
Liver cancer with liver tissue array |
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LV803b | TissueArray | each | EUR 270 |
Description: Liver cancer with liver tissue array, including pathology grade, TNM and clinical stage, 54 cases/72 cores, replacing LV803a |
Soft tissue cancer test tissue array |
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T241 | TissueArray | each | EUR 48 |
Description: Soft tissue cancer test tissue array, with normal soft tissue control tissue, including TNM, clinical stage and pathology grade, 6 cases/24 cores |
Oral cavity cancer test tissue array |
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T273 | TissueArray | each | EUR 66 |
Description: Oral cavity cancer test tissue array, with normal tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases/24 cores |
Schwann cell culture model suggests that miR-150-5p is a strong negative regulator of genes CREB, BDNF and NGF. Identification of deregulated miRNAs may help in understanding the complex underlying pathomechamism ATTRv development and related multisystemic pathology. Further investigation is needed on the role of circulating miR-150-5p to predict shifts TTRv operator of asymptomatic status appearance of symptoms.