Objective: High incidence of and deaths from unstable angina (UA) is, for the most part, a consequence of the lack of highly sensitive and specific non-invasive markers. Circulating microRNAs (miRNAs) have been widely recommended as potential biomarkers for various diseases. In this study, we characterized the typical miRNA expression profile in patients with stable angina (SA), UA, and normal coronary arteries (NCA), and identify promising candidates for the diagnosis of UA.

Methods: Serum collected from patients with SA, UA, and NCA who visited the Department of Cardiovascular Diseases Meizhou People’s Hospital. Small RNA sequencing performed on the Illumina HiSeq 2500 platform. MiRNA expression in different groups of patients profiled and then confirmed by that in an independent set of patients. The function of miRNAs are expressed differently allegedly using gene ontology classification and Kyoto Encyclopedia of Genes and Genomes pathway analysis.

Results: Our results suggest that circulating miRNA expression profiles differ between SA, UA, and patient NCA. A total of 36 and 161 miRNAs are dysregulated in SA and UA patients, respectively. validated miRNA

expression by reverse transcription quantitative polymerase chain reaction.
Conclusion: The results showed that circulating miRNAs are potential biomarkers UA. There is a positive correlation between birth weight and BMI pregestational pregnant individuals (r = 0.48, P <0.001). One hundred and eight miRNAs were differentially expressed between normal and overweight / obese group, which target genes are enriched in the metabolic pathways.

C19MC five miRNAs (miR-516a-5p, miR-516b-5p, miR-520A-3p, miR-1323, mir-523-5p) were upregulated in overweight / obese group. Target enrichment analysis indicates their involvement in the post-embryonic development, lipid and glucose homeostasis, differentiation of T cells and the development of the nervous system.

Circulating microRNAs profile variant transthyretin amyloidosis patients

Variant transthyretin amyloidosis (ATTRv) is a rare autosomal dominant disease characterized by the accumulation of amyloid in many organs, most cause sensory-motor neuropathy, cardiomyopathy, and dysautonomia. The purpose of this study was to report the profiles of microRNAs (miRNAs) expression ATTRv identified in patients’ blood.

ATTRv ten patients, 10 asymptomatic carriers of the variant transthyretin (TTRv), 10 patients with Charcot-Marie-Tooth disease (CMT), and 10 healthy controls were studied. Human Schwann cell cultures were used to study the regulation of miR-150-5p effect on the expression of cAMP response element-binding protein (CREB), brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF).

ATTRv patients had 33 miRNAs up-regulated and 48 down-regulated compared to healthy controls; 9 miRNAs up-and-regulated and 30 down-regulated compared CMT patients; 19 miRNAs up-and-regulated and 38 down-regulated compared TTRv asymptomatic carriers. Twelve of the 19 miRNAs upregulated have fold higher than 100. The validation study showed miR-150-5p as a valuable biomarker for patients ATTRv TTRv distinguish from asymptomatic carriers (AUC: 0.9728; p <0.0001).

Kidney cancer tissue array
BC07014b	TissueArray	each	EUR 168
Description: Kidney cancer tissue array, including pathology grade, TNM and clinical stage, 72 cases/72 cores, replacing BC07014a

Endometrium cancer tissue array
BC09012b	TissueArray	each	EUR 270
Description: Endometrium cancer tissue array, including pathology grade, TNM and clinical stage(AJCC 8th edition), 63 cases/63 cores, replacing BC09012a

Bladder cancer tissue array
BC12011c	TissueArray	each	EUR 186
Description: Bladder cancer tissue array, including TNM, 63 cases/63 cores (core size 1.5mm)

Prostate cancer tissue array
BC19021a	TissueArray	each	EUR 306
Description: Prostate cancer tissue array, with adjacent tissue and normal tissue, including TNM and pathology grade, 28 cases/72 cores, replacing BC19021

Bladder cancer tissue array
BL2082a	TissueArray	each	EUR 546
Description: Bladder cancer tissue array, including TNM, clinical stage and pathology grade, 208 cases/ 208 cores, replacing BL2082

Bladder cancer tissue array
BL2082B	TissueArray	each	EUR 546
Description: Bladder cancer tissue array, including TNM and clinical stage, 208 cases/208 cores, replacing BL2082a

Bladder cancer tissue array
BL242	TissueArray	each	EUR 270
Description: Bladder cancer tissue array, with normal tissue, including TNM and pathology grade, 24 cases/48 cores

Breast cancer tissue array
BR042b	TissueArray	each	EUR 78
Description: Breast cancer tissue array, including TNM and pathology grade, 4 cases/4 cores, replacing BR042a

Breast cancer tissue array
BR1006a	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 50 cases/100 cores (core size 1.0mm), replacing BR1006

Breast cancer tissue array
BR1141a	TissueArray	each	EUR 354
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, IHC marker (ER, PR, HER2 and Ki-67), 114 cases/114 cores, replacing BR1141

Breast cancer tissue array
BR1401	TissueArray	each	EUR 414
Description: Breast cancer tissue array, including TNM and pathology grade, IHC markers ER/PR/Her-2 results, 140 cases/140 cores (core size 1.0mm)

Breast cancer tissue array
BR1503f	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including TNM and pathology grade, with IHC results of Her-2\ER\PR\Ki67, 75 cases/ 150 cores, replacing BR1503e

Breast cancer tissue array
BR1505e	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage, and IHC(HER2/ER/PR/Ki67), 75 cases/150 cores, replacing BR1505d

Breast cancer tissue array
BR2161	TissueArray	each	EUR 546
Description: Breast cancer tissue array, including TNM and pathology grade, 216 cases/216 cores

Breast cancer tissue array
BR247a	TissueArray	each	EUR 234
Description: Breast cancer tissue array, with normal tissue, including TNM and pathology grade, IHC marker (HER2), 24 cases/48 cores replacing BR247

Breast cancer tissue array
BR488	TissueArray	each	EUR 306
Description: Breast cancer tissue array, including pathology grade, TNM, clinical stage (AJCC 7th edition), and IHC marker(ER,PR,Her-2), 48 cases/48 cores

Breast cancer tissue array
BR501	TissueArray	each	EUR 270
Description: Breast cancer tissue array, including TNM and pathology grade, 50 cases/ 50 cores (core size 1.5mm)

Breast cancer tissue array
BR8015a	TissueArray	each	EUR 306
Description: Breast cancer tissue array, with adjacent normal tissue and normal tissue, including TNM and pathology grade, 80 cases/80 cores, replacing BC08014

Breast cancer tissue array
BR964	TissueArray	each	EUR 222
Description: Breast cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Stomach cancer tissue array
BS01012e	TissueArray	each	EUR 270
Description: Stomach cancer tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition), 72 cases/72 cores, replacing BS01012d

Colon cancer tissue array
CO1502	TissueArray	each	EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Colon cancer tissue array
CO1503	TissueArray	each	EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Colon cancer tissue array
CO244	TissueArray	each	EUR 270
Description: Colon cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Colon cancer tissue array
CO485	TissueArray	each	EUR 270
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/48 cores

Colon cancer tissue array
CO486a	TissueArray	each	EUR 414
Description: Colon cancer tissue array, including pathology grade, TNM and clinical stage, 2 serial sections, 48 cases/96 cores, replacing CO486

Colon cancer tissue array
CO641	TissueArray	each	EUR 258
Description: Colon cancer tissue array, including TNM, stage and pathology grade, 64 cases/ 64 cores

Colon cancer tissue array
CO804b	TissueArray	each	EUR 270
Description: Colon cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores, replcing CO804a

Colon cancer tissue array
CO901a	TissueArray	each	EUR 306
Description: Colon cancer tissue array, with adjacent normal colon tissue, including TNM, clinical stage and pathology grade, 50 cases/90 cores, replacing CO901

Colon cancer tissue array
CO961	TissueArray	each	EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Colon cancer tissue array
CO962	TissueArray	each	EUR 258
Description: Colon cancer tissue array, including pathology grade, TNM/Stage, 48 cases/96 cores

Cervical cancer tissue array
CR1501	TissueArray	each	EUR 258
Description: Cervical cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Colorectal cancer tissue array
CRM1502	TissueArray	each	EUR 420
Description: Colorectal cancer tissue array, 150 cases/150 cores

Colon cancer tissue array
CRM1503	TissueArray	each	EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colon cancer tissue array
CRM1504	TissueArray	each	EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colorectal cancer tissue array
CRM1505	TissueArray	each	EUR 420
Description: Colorectal cancer tissue array, 150 cases/150 cores

Colon cancer tissue array
CRM1506	TissueArray	each	EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Colon cancer tissue array
CRM1507	TissueArray	each	EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Endocrine cancer tissue array
EN801b	TissueArray	each	EUR 306
Description: Endocrine cancer tissue array, including TNM and clinical stage, 40 cases/80 cores, replacing EN801a

Esophageal cancer tissue array
ES1502	TissueArray	each	EUR 258
Description: Esophageal cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Esophagus cancer tissue array
ES243	TissueArray	each	EUR 270
Description: Esophagus cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Esophageal cancer tissue array
ES481	TissueArray	each	EUR 198
Description: Esophageal cancer tissue array with matched or unmatched normal adjacent tissues (18 cases/48 cores) with stage and grade info

Esophagus cancer tissue array
ES781	TissueArray	each	EUR 306
Description: Esophagus cancer tissue array, including pathology grade, TNM and clinical stage, 16 cases/78 cores, replacing BC02111

Kidney cancer tissue array
KD245	TissueArray	each	EUR 66
Description: Kidney cancer tissue array, including TNM, clinical stage and pathology grade, 24 cases/ 24 cores

Kidney cancer tissue array
KD485	TissueArray	each	EUR 168
Description: Kidney cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores

Lung cancer tissue array
LC1261	TissueArray	each	EUR 354
Description: Lung cancer tissue array, including pathology grade, TNM, clinical stage and PD-L1 (Sp263) information, 63 cases/126 cores

Lung cancer tissue array
LC243	TissueArray	each	EUR 198
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Lung cancer tissue array
LC485	TissueArray	each	EUR 198
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores

Lung cancer tissue array
LC721	TissueArray	each	EUR 270
Description: Lung cancer tissue array, including TNM and pathology grade, 24 cases/72 cores

Lung cancer tissue array
LC726b	TissueArray	each	EUR 222
Description: Lung cancer tissue array, including TNM, clinical stage and pathology grade, 72 cases/72 cores, replacing LC726

Lung cancer tissue array
LUN703	TissueArray	each	EUR 198
Description: Lung cancer tissue array,including pathology grade and TNM,7 cases/70 cores (core size 1.5mm)

Liver cancer tissue array
LV1002	TissueArray	each	EUR 306
Description: Liver cancer tissue array, including TNM, clinical stage and pathology grade, 50 cases/100 cores

Liver cancer tissue array
LV1502	TissueArray	each	EUR 258
Description: Liver cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Liver cancer tissue array
LV2161	TissueArray	each	EUR 546
Description: Liver cancer tissue array, with normal tissue, including TNM and pathology grade, 216 cases/216 cores

Liver cancer tissue array
LV245	TissueArray	each	EUR 198
Description: Liver cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Multiple cancer tissue array
MC801	TissueArray	each	EUR 306
Description: Multiple cancer tissue array, replacing BC00012, 80 cases/80 cores, with grade information

Lymphoma cancer tissue array
NHL482a	TissueArray	each	EUR 222
Description: Lymphoma cancer tissue array, 48 cases/48 cores, replacing NHL482

Lung cancer tissue array
NSC151	TissueArray	each	EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array
NSC153	TissueArray	each	EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array
NSC154	TissueArray	each	EUR 420
Description: Lung cancer tissue array, with ALK results,, 150 cases/150 cores

Lung cancer tissue array
NSC155	TissueArray	each	EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array
NSC156	TissueArray	each	EUR 420
Description: Lung cancer tissue array, 150 cases/150 cores

Lung cancer tissue array
NSC157	TissueArray	each	EUR 420
Description: Lung cancer tissue array, 150 cases/150 cores

Ovarian cancer tissue array
OV0071a	TissueArray	each	EUR 42
Description: Ovarian cancer tissue array, including TNM/Stage (AJCC 8th edition), 7cases/7 cores (core size 1.5mm)

Ovarian cancer tissue array
OV484b	TissueArray	each	EUR 270
Description: Ovarian cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/48 cores, replacing OV484a

Ovarian cancer tissue array
OV801b	TissueArray	each	EUR 270
Description: Ovarian cancer tissue array, with matched (B7/F7, B8/F8, C3/F3) or unmatched adjacent tissue array, 80 cases/80 cores, replacing OV801

Pancreatic cancer tissue array
PA1001D	TissueArray	each	EUR 306
Description: Pancreatic cancer tissue array, with adjacent normal pancreas tissue and normal pancreas tissue, including TNM and pathology grade, 50 cases/100 cores, replacing PA1001c

Pancreatic cancer tissue array
PA2072a	TissueArray	each	EUR 546
Description: Pancreatic cancer tissue array, with normal tissue, including TNM and pathology grade, 69 cases/207 cores, replacing PA2072

Pancreatic cancer tissue array
PA501	TissueArray	each	EUR 270
Description: Pancreatic cancer tissue array, including TNM and pathology grade, 50 cases/50 cores (core size 1.5mm)

Pancreatic cancer tissue array
PA807	TissueArray	each	EUR 306
Description: Pancreatic cancer tissue array, with cancer adjaceent tissue and normal tissue as control, including duct adenocarcinoma(PADC), cancer adjaceent pancreatic and normal tissue TNM, clinical stage and pathology grade, 80 cases/ 80 cores(1.5mm)

Prostate cancer tissue array
PR1001	TissueArray	each	EUR 306
Description: Prostate cancer tissue array, including WHO pathology grade and gleason grade, 25 cases/100 cores

Prostate cancer tissue array
PR483d	TissueArray	each	EUR 198
Description: Prostate cancer tissue array, including TNM, clinical stage and pathology grade, with Gleason score and WHO grade, 48 cases/48 cores, replacing PR483c

Prostate cancer tissue array
PR484a	TissueArray	each	EUR 138
Description: Prostate cancer tissue array, including WHO standerd grade, Gleason grade, Gleason score, TNM and clinical stage, 24 cases/48 cores (core size 1.5mm), replacing PR484

Prostate cancer tissue array
PR633a	TissueArray	each	EUR 306
Description: Prostate cancer tissue array, including TNM, clinical stage and pathology grade, 63 cases/63 cores, replacing PR633

Rectum cancer tissue array
RE1503	TissueArray	each	EUR 258
Description: Rectum cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Stomach cancer tissue array
ST484d	TissueArray	each	EUR 252
Description: Stomach cancer tissue array, including TNM and pathology grade and HER-2 result, 48 cases/48 cores

Liver cancer tissue array
T031c	TissueArray	each	EUR 66
Description: Liver cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24cores(1,5mm), replacing T031b

Breast cancer tissue array
T089c	TissueArray	each	EUR 48
Description: Breast cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores(1.5mm), replacing T089b

Cervical cancer tissue array
T104	TissueArray	each	EUR 48
Description: Cervical cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores

Cervix cancer tissue array
T104a	TissueArray	each	EUR 48
Description: Cervix cancer tissue array, including squamous cell carcinoma, glassy cell carcinoma and adenocarcinoma, pathology grade, TNM and clinical stage, 6 cases/24 cores (1.5mm), replacing T104

Ovarian cancer tissue array
T111a	TissueArray	each	EUR 48
Description: Ovarian cancer tissue array, with normal ovary tissue, including TNM and pathology grade, 6 cases/24 cores(1.5mm), replacing T111

Ovarian cancer tissue array
T114a	TissueArray	each	EUR 48
Description: Ovarian cancer tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T114

Pancreatic cancer tissue array
T144a	TissueArray	each	EUR 48
Description: Pancreatic cancer tissue array, including TNM, clinical stage and pathology grade, 6 cases/24 cores, replacing T144

Thyroid cancer tissue array
T152	TissueArray	each	EUR 48
Description: Thyroid cancer tissue array, including TNM and pathology grade, 6 cases/24 cores

Cerebrum cancer tissue array
T173b	TissueArray	each	EUR 66
Description: Cerebrum cancer tissue array, with normal tissue, including pathology grade, 2 serial sections, 6 cases/ 24 cores, replacing T173a

Endometrium cancer tissue array
UT242a	TissueArray	each	EUR 270
Description: Endometrium cancer tissue array, with normal tissue, including TNM and pathology grade, 24 cases/24 cores

Endometrium cancer tissue array
UT481	TissueArray	each	EUR 270
Description: Endometrium cancer tissue array, including TNM and pathology grade, 48 cases/48 cores

Endometrium cancer tissue array
UT961	TissueArray	each	EUR 222
Description: Endometrium cancer tissue array, including TNM, clinical stage and pathology grade, 48 cases/96 cores

Vulva cancer tissue array
UV241a	TissueArray	each	EUR 66
Description: Vulva cancer tissue array, including TNM, clinical stage and pathology diagnosis, replacing UV241

Lung cancer tissue array
VLC11	TissueArray	each	EUR 66
Description: Lung cancer tissue array, with TNM and grade info, 11 cases/11 cores

Lung cancer tissue array
VLC12b	TissueArray	each	EUR 66
Description: Lung cancer tissue array, including pathology grade, TNM and clinical stage, 12 cases/12 cores, replacing VLC12a

LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles
RA900A-1	SBI	20 profiles	EUR 1020

Colon cancer and lung cancer tissue array
CLC601	TissueArray	each	EUR 306
Description: Colon cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores

Stomach cancer and lung cancer tissue array
SLC601	TissueArray	each	EUR 306
Description: Stomach cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores

Colon cancer with cancer adjacent tissue array
T051b	TissueArray	each	EUR 48
Description: Colon cancer with cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T051a

PLATEMAX ULTRA CLEAR PERMANENT HEAT SEALING FILM FOR QPCR, 100/500
HS-100-QPCR	CORNING	100/pk	EUR 381.6
Description: Sealing Products; Sealing films - Axygen

PLATEMAX ULTRA CLEAR PEELABLE HEAT SEALING FILM FOR QPCR. 100/500
HS-150-QPCR	CORNING	100/pk	EUR 381.6
Description: Sealing Products; Sealing films - Axygen

Mouse LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles
RA930A-1	SBI	20 profiles	EUR 1020

Breast cancer tissue array and normal tissue array
BR726	TissueArray	each	EUR 306
Description: Breast cancer tissue array and normal tissue array, with TNM and grade, 24 cases/72 cores

Colon cancer test tissue array (4x (2x3) array)
T055a	TissueArray	each	EUR 48
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055

Colon cancer test tissue array (4x (2x3) array)
T055b	TissueArray	each	EUR 48
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055a

Kidney cancer test tissue array (4x (2x3)array)
T074a	TissueArray	each	EUR 48
Description: Kidney cancer test tissue array (4x (2x3)array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T074

Prostate cancer test tissue array (4x (2x3) array)
T196a	TissueArray	each	EUR 66
Description: Prostate cancer test tissue array (4x (2x3) array), including pathology grade, Gleason grade, Gleason score, TNM and clinical stage, 6 cases/24 cores, replacing T196

Multiple organ cancer tissue array
BC000111b	TissueArray	each	EUR 168
Description: Multiple organ cancer tissue array, including TNM, clinical stage and pathology grade, 39 cases/39 cores, replacing BC000111a

Multiple organ cancer tissue array
BC000119b	TissueArray	each	EUR 546
Description: Multiple organ cancer tissue array, including pathology grade, TNM, clinical stage, Gleason grade and Gleason score, 190 cases/190 cores, replacing BC000119a

Multiple organ cancer tissue array
BC000120b	TissueArray	each	EUR 546
Description: Multiple organ cancer tissue array, including pathology grade, TNM and clinical stage, 190 cases/190 cores, replacing BC000120a

Gastroesophageal junction cancer tissue array
CA301-1	TissueArray	each	EUR 306
Description: Gastroesophageal junction cancer tissue array, including TNM, clinical stage and pathology grade, 30 cases/ 30 cores

Uterine cervix cancer tissue array
CR244	TissueArray	each	EUR 66
Description: Uterine cervix cancer tissue array, with adjacent normal tissue, including TNM and pathology grade, 12 cases/24 cores, replacing CR241

Esophageal cancer progression tissue array
ES804	TissueArray	each	EUR 270
Description: Esophageal cancer progression tissue array, 76 cases/80 cores

Metastatic esophageal cancer tissue array
ES806	TissueArray	each	EUR 306
Description: Metastatic esophageal cancer tissue array, 40 cases/80 cores

Kidney cancer survey tissue array
KD2085	TissueArray	each	EUR 474
Description: Kidney cancer survey tissue array, no overlapping with KD2089, including TNM, clinical stage and pathology grade, 104 cases/208 cores

Kidney cancer survey tissue array
KD2089	TissueArray	each	EUR 474
Description: Kidney cancer survey tissue array, no overlapping with KD2085, including TNM and pathology grade, 104 cases/208 cores

High-density renal cancer array
KD6161	TissueArray	each	EUR 954
Description: High-density renal cancer array, with stage, grade and normal renal tissue, 322 cases/616 cores

Lung cancer progression tissue array
LC1005b	TissueArray	each	EUR 270
Description: Lung cancer progression tissue array, including TNM, clinical stage and pathology grade, 100 cases/100 cores, replacing LC1005a

Multiple lung cancer tissue array
LC20813c	TissueArray	each	EUR 546
Description: Multiple lung cancer tissue array, including pathology grade, TNM and clinical stage, 192 cases/192 cores, replacing LC120813b

Multiple lung cancer tissue array
LC20815a	TissueArray	each	EUR 546
Description: Multiple lung cancer tissue array, including pathology grade, TNM and clinical stage (small cell carcinoma is referenced AJCC 8th version), 208 cases/208 cores, replacing LC20815

High-density lung cancer array
LC6161	TissueArray	each	EUR 954
Description: High-density lung cancer array, with stage, grade and normal lung tissue, 322 cases/616 cores

Liver cancer antibody screening array
LV1001	TissueArray	each	EUR 306
Description: Liver cancer antibody screening array, including TNM, clinical stage and pathology grade, 25 cases/100 cores

Multiple organ cancer tissue array
MC543	TissueArray	each	EUR 354
Description: Multiple organ cancer tissue array, including TNM and pathology grade, 54 cases/ 54 cores

Liver metastatic cancer tissue array
MLV801	TissueArray	each	EUR 354
Description: Liver metastatic cancer tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores

Stomach cancer tissue test array
T011b	TissueArray	each	EUR 48
Description: Stomach cancer tissue test array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T011a

Stomach cancer test tissue array
T014a	TissueArray	each	EUR 48
Description: Stomach cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores replacing T014

Lung cancer test tissue array
T046a	TissueArray	each	EUR 48
Description: Lung cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T046

Kidney cancer test tissue array
T072b	TissueArray	each	EUR 48
Description: Kidney cancer test tissue array, with normal control tissue, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T072a

Breast cancer test tissue array
T086e	TissueArray	each	EUR 66
Description: Breast cancer test tissue array, including TNM, clinical stage and pathology grade, 12 cases/24 cores, replacing T086d

Uterus cancer test tissue array
T093	TissueArray	each	EUR 78
Description: Uterus cancer test tissue array, with normal endometrial tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases/24 cores

Prostate cancer test tissue array
T195d	TissueArray	each	EUR 66
Description: Prostate cancer test tissue array, including TNM, Gleason score and pathology grade, 12 cases/24 cores, replaced by T195e

Testis cancer test tissue array
T233	TissueArray	each	EUR 66
Description: Testis cancer test tissue array, with normal tissue as control, including TNM and clinical stage, 2 serial sections, 6 cases/24 cores

Appendix cancer test tissue array
T413	TissueArray	each	EUR 66
Description: Appendix cancer test tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 6 cases/24 cores

Breast cancer with cancer adjacent breast tissue array
BC081116e	TissueArray	each	EUR 306
Description: Breast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type, breast carcinoma with apocrine differentiation and AT tissue,pat hology grade, IHC (ER/PR/Her-2/Ki67) info, TNM/Stage (AJCC 7th edition), 107 cases/110 cores (core size 1.5mm), replacing BC081116d

Cervix cancer tissue array with cancer adjacent tissue
CR501a	TissueArray	each	EUR 234
Description: Cervix cancer tissue array with cancer adjacent tissue, including TNM, clinical stage and pathology grade, 50 cases/50 cores, replacing CR501

Pancreatic cancer tissue array with cancer adjacent tissue
PA242e	TissueArray	each	EUR 66
Description: Pancreatic cancer tissue array with cancer adjacent tissue, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing PA242d

Prostate cancer tissue array with cancer adjacent tissues
PR721	TissueArray	each	EUR 306
Description: Prostate cancer tissue array with cancer adjacent tissues, including WHO grade, gleason grade, gleason score, TNM and stage info, 24 cases/72 cores

Stomach cancer with matched cancer adjacent tissue array
ST1504	TissueArray	each	EUR 258
Description: Stomach cancer with matched cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 50 cases/150 cores

Colon cancer tissue array with matched cancer adjacent tissue
BC05023a	TissueArray	each	EUR 270
Description: Colon cancer tissue array with matched cancer adjacent tissue, including TNM and pathology grade, 18 cases/ 54 cores, replacing BC05023

Breast cancer with matched cancer adjacent breast tissue array
BR804b	TissueArray	each	EUR 306
Description: Breast cancer with matched cancer adjacent breast tissue array, including pathology grade, TNM, clinical stage and IHC markers (ER, PR, Her-2 and Ki67), 40 cases/80 cores, replacing BR804a

Colon cancer tissue array with matched cancer adjacent tissue
CO801b	TissueArray	each	EUR 270
Description: Colon cancer tissue array with matched cancer adjacent tissue, including pathology grade, TNM and clinical stage, 40 cases/80 cores, replcing CO801a

Esophagus cancer with matched cancer adjacent esophagus tissue array
ES1025	TissueArray	each	EUR 354
Description: Esophagus cancer with matched cancer adjacent esophagus tissue array, including pathology grade, TNM and clinical stage (AJCC 8.0), 51 cases/102 cores (1.5 mm).

Lung cancer with matched cancer adjacent lung tissue array
LC481	TissueArray	each	EUR 168
Description: Lung cancer with matched cancer adjacent lung tissue array, including pathology grade, TNM and clinical stage, 12 cases/48 cores

Liver cancer with matched cancer adjacent liver tissue array
LV1505a	TissueArray	each	EUR 258
Description: Liver cancer with matched cancer adjacent liver tissue array, including pathology grade, TNM and clinical stage, replacing LV1505

Liver cancer and liver tissue array
BC03116a	TissueArray	each	EUR 306
Description: Liver cancer and liver tissue array, including pathology grade, TNM and clinical stage, 70 cases/70 cores, replacing BC03116

Liver cancer and normal tissue array
BC03116b	TissueArray	each	EUR 306
Description: Liver cancer and normal tissue array, including pathology grade, TNM and clinical stage, 70 cases/70 cores, replacing BC03116a

Colon cancer and normal tissue array
BC051111	TissueArray	each	EUR 546
Description: Colon cancer and normal tissue array, including TNM, clinical stage and pathology grade, 100 cases/200 cores

Breast cancer with breast tissue array
BC08118a	TissueArray	each	EUR 258
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 100 cases/100 cores (core size 1.0mm), replacing BC08118

Prostate cancer and hyperplasia tissue array
BC19017b	TissueArray	each	EUR 270
Description: Prostate cancer and hyperplasia tissue array, including pathology grade, TNM and clinical stage, 32 cases/ 63 cores, replacing BC19017a

Bladder cancer and normal tissue array
BL1002b	TissueArray	each	EUR 306
Description: Bladder cancer and normal tissue array, including pathology grade, TNM and clinical stage, 50 cases/ 100 cores, replacing BL1002a

Bladder cancer with bladder tissue array
BL2081C	TissueArray	each	EUR 545
Description: Bladder cancer with bladder tissue array, including pathology grade, TNM and clinical stage, 191 cases/192 cores, replacing BL2081b

Bladder cancer with bladder tissue array
BL243a	TissueArray	each	EUR 78
Description: Bladder cancer with bladder tissue array, including urothelial carcinoma,squamous cell carcinoma, adenocarcinoma and normal tissue, pathololy grade, TNM and clinical stage (AJCC 8.0), 12 case/24 cores (1.5mm), replacing BL243

Bladder cancer with bladder tissue array
BL481d	TissueArray	each	EUR 198
Description: Bladder cancer with bladder tissue array, including urothelial carcinoma, squamous cell carcinoma, adenocarcinoma and normal tissue, TNM/Stage, 48 cases/48 cores (core size 2.0 mm), replacing BL481d

Bladder cancer and bladder tissue array
BL806b	TissueArray	each	EUR 306
Description: Bladder cancer and bladder tissue array, including pathology grade, TNM and clinical stage, 60 cases/80 cores, replacing BL806a

Bladder cancer with bladder tissue array
BL807	TissueArray	each	EUR 306
Description: Bladder cancer with bladder tissue array, including TNM and clinical stage, 80 cases/80 cores

Multiple types breast cancer tissue array
BR1003a	TissueArray	each	EUR 306
Description: Multiple types breast cancer tissue array, including pathology grade, TNM and clinical stage, 47 cases/101 cores, replacing BR1003

Late stage breast cancer tissue array
BR1922	TissueArray	each	EUR 546
Description: Late stage breast cancer tissue array, including TNM, clinical stage and pathology grade, 96 cases/192 cores

Breast cancer with breast tissue array
BR2085d	TissueArray	each	EUR 546
Description: Breast cancer with breast tissue array, including pathology grad, TNM and clinical stage, 188 cases/208 cores, replacing BR2085c

Breast cancer with breast tissue array
BR246d	TissueArray	each	EUR 66
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 12 cases/24 cores, replacing BR246c

Poorly differentiated breast cancer tissue array
BR351a	TissueArray	each	EUR 66
Description: Poorly differentiated breast cancer tissue array, including TNM, clinical stage and pathology grade, 35 cases/35 cores, replacing BR351

Breast cancer with breast tissue array
BR482	TissueArray	each	EUR 198
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical stage, 24 cases/48 cores

Breast cancer and normal tissue array
BR485	TissueArray	each	EUR 414
Description: Breast cancer and normal tissue array, including TNM and pathology grade, 2 serial sections, 48 cases/96 cores

High-density breast cancer tissue array
BR6161	TissueArray	each	EUR 954
Description: High-density breast cancer tissue array, with stage, grade and normal breast tissue, 322 cases/616 cores

Breast cancer with breast tissue array
BR720	TissueArray	each	EUR 270
Description: Breast cancer with breast tissue array, including pathology grade, TNM and clinical satge (reference AJCC 7th version), 72 cases/72 cores

Breast cancer and normal tissue array
BR8014	TissueArray	each	EUR 306
Description: Breast cancer and normal tissue array, including TNM, clinical stage and pathology grade, 40 cases/80 cores, replaced by BR8015

Gastroesophageal junction (GEJ) cancer tissue array
CA941	TissueArray	each	EUR 306
Description: Gastroesophageal junction (GEJ) cancer tissue array, including TNM, clinical stage and pathology grade, 94 cases/94 cores, replaced by CA941a

Gastroesophageal junction (GEJ) cancer tissue array
CA941a	TissueArray	each	EUR 306
Description: Gastroesophageal junction (GEJ) cancer tissue array, including pathology grade, TNM and clinical stage, 94 cases/94 cores, replacing GA941

Schwann cell culture model suggests that miR-150-5p is a strong negative regulator of genes CREB, BDNF and NGF. Identification of deregulated miRNAs may help in understanding the complex underlying pathomechamism ATTRv development and related multisystemic pathology. Further investigation is needed on the role of circulating miR-150-5p to predict shifts TTRv operator of asymptomatic status appearance of symptoms.