Treatment with Tang-luo-ning altered the microRNA expression profile in rats with diabetic peripheral neuropathy

Tang-luo-ning (TLN) is a traditional Chinese herbal recipe that has been used to treat diabetic peripheral neuropathy (DPN); However, the underlying mechanisms are still unclear. This study aims to investigate microRNA (miRNA) expression profiles in diabetic rats treated with TLN, and the predicted target genes. Male Sprague-Dawley rats were randomly divided into control, diabetes, and TLN-treated diabetic groups. Diabetes was induced with streptozotocin, and TLN (5 g / kg / day) orally administered for eight weeks.

Then, the sciatic nerve is harvested for miRNA microarray analysis. The differentially expressed miRNAs and their target genes analyzed. Compared with control mice, 24 miRNAs were significantly upregulated and 59 were downregulated in the sciatic nerves of diabetic mice with more than two-fold (all P <0.05). On TLN-treated diabetic mice, 26 miRNAs were upregulated and 14 downregulated compared with diabetic mice without treatment TLN (all P <0.05). DPN-induced changes of miRNA profiles TLN reversed with treatment.

A total of 1,402 of the target genes screened. In the GO analysis, gene localization, cytoplasm, and the enriched protein binding, and the most significantly enriched including neurotrophin, Fc epsilon RI, and the Wnt signaling pathway. Further analysis revealed that DVL1 and NTF3 genes involved in this pathway. Our findings suggest that TLN can affect Wnt and neurotrophin pathway by acting on the genes DVL1 and NTF3.

 Treatment with Tang-luo-ning altered the microRNA expression profile in rats with diabetic peripheral neuropathy
Treatment with Tang-luo-ning altered the microRNA expression profile in rats with diabetic peripheral neuropathy

Find signatures of lupus-related microRNA profile in the Gene Expression Omnibus repository

Lupus is one of the most common autoimmune disease systemic. It is a multifactorial disease that is genetic, epigenetic and environment plays a significant role. The pathogenesis of lupus is not well understood. However, deregulation of microRNAs (miRNAs) – one of the post-transcriptional regulators of gene – may contribute to the development of autoimmune disease.

Over the past two decades, advances in miRNA profiling using microarray has received a lot of attention, and it has been demonstrated that miRNAs play a regulatory role in the pathogenesis of lupus. Therefore, dysregulated miRNAs can be considered as a promising diagnostic biomarker for lupus. This article is an overview of lupus-related miRNA array profiles and studies in the Gene Expression Omnibus (GEO) database. The aim of our research is to expand the current knowledge dysregulated miRNAs known as a potential biomarker of SLE and to introduce a bioinformatics approach to using microarray data and find novel miRNA and gene candidates for further study. We identified HSA-miR-4709-5p, HSA-mir-140, mir-145-HSA, HSA-mir-659, mir-134-HSA, HSA-mir-150, mir-584-HSA, HSA-Mirza HSA-409 and miR-152 as a potential biomarker with integrated bioinformatics analysis.

Microsome Isolation Kit

K249-50 each
EUR 633.6

Preadipocyte Isolation Kit

K583-5 each
EUR 639.6

Apoptotic Cell Isolation Kit

55R-1349 30 units
EUR 874.8
Description: Apoptotic Cell Isolation Kit for use in the research laboratory

Mitochondrial DNA Isolation Kit

55R-1361 50 assays
EUR 990
Description: Mitochondrial DNA Isolation Kit for use in the research laboratory

Genomic DNA Isolation Kit

55R-1362 50 assays
EUR 462
Description: Genomic DNA Isolation Kit for use in the research laboratory

Cell Mitochondria Isolation Kit

abx090630-50100tests 50-100 tests
EUR 309.6

Tissue Mitochondria Isolation Kit

abx090631-50100assays 50-100 assays
EUR 309.6

Lipid Droplet Isolation Kit

MET-5011 50 preps
EUR 498
Description: Lipid droplets are lipid rich organelles found in the adipose tissue of eukaryotes. They function to regulate the hydrolysis and storage of neutral lipids and serve as storage for cholesterol and acyl-glycerols. Lipid droplets have also been associated with inflammatory responses, obesity, atherosclerosis, and cancer.

Easy3-RNA Isolation Kit

FYG501-100P 100 Preps Ask for price

Easy3-RNA Isolation Kit

FYG501-500P 500 Preps Ask for price

Serum DNA Isolation Kit

K5018100 1 kit
EUR 432

Saliva DNA Isolation Kit

K5011050 1 kit
EUR 307.2

Urine DNA Isolation Kit

K5011150 1 kit
EUR 307.2

Stool DNA Isolation Kit

K5011250 1 kit
EUR 307.2

Cartilage RNA Isolation Kit

K2031010 1 kit
EUR 502.8
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Mitochondrial DNA Isolation Kit

K2117-50 50 assays
EUR 718.8

Genomic DNA Isolation Kit

K2118-50 50 assays
EUR 385.2

Total RNA Isolation Kit

P-9100 50 samples
EUR 416.7

ExoPure? Isolation Kit   (Urine)

K1240-10 each
EUR 836.4

ExoPure? Isolation Kit   (Urine)

K1240-2 each
EUR 483.6

Apoptotic Cell Isolation Kit

K258-30 each
EUR 561.6

Yeast Mitochondria Isolation Kit

K259-50 each
EUR 502.8

Mitochondrial DNA Isolation Kit

K280-50 each
EUR 705.6

Genomic DNA Isolation Kit

K281-50 each
EUR 326.4

Yeast Nuclei Isolation Kit

K289-50 each
EUR 470.4

Lipopolysaccharide (LPS) Isolation Kit

K438-10 each
EUR 333.6

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Rapid Bacteria RNA Isolation Kit

BS8625 50Preps
EUR 95.63

Rapid Blood RNA Isolation Kit

BT4182 10Preps
EUR 98.36

Rapid Blood RNA Isolation Kit

BT4183 50Preps
EUR 197.03

Rapid Blood RNA Isolation Kit

BT4184 250preps
EUR 608.1

Circulating Nuleic Acid Isolation Kit

FACFK-050 50 preps
EUR 589.2

Circulating Nuleic Acid Isolation Kit

FACFK-100 100 preps
EUR 990

Total RNA Isolation Kit II

FATRS--001 100 preps
EUR 369.6

Total RNA Isolation Kit II

FATRS--050 50 preps
EUR 259.2

Exo-Urine EV Isolation Kit

EXOU100A-1 2 x 5 reactions
EUR 661.2

Easy3-Plant RNA Isolation Kit

FYG502-100P 100 Preps Ask for price

Easy3-Plant RNA Isolation Kit

FYG502-500P 500 Preps Ask for price

Easy3-Total NucleicAcid Isolation Kit

FYG504-100ML 100 ml Ask for price

Easy3-Total NucleicAcid Isolation Kit

FYG504-500ML 500 ml Ask for price

Genoirse Plant DNA Isolation Kit

GR101083 50
EUR 267.6

Apoptotic DNA Ladder Isolation Kit

K2045-50 50 assays
EUR 602.4

Rapid Plant RNA Isolation Kit

PT4191 50Preps
EUR 95.63

FitAmp Urine DNA Isolation Kit 

P-1017-050 50 Samples
EUR 171.6

FitAmp Urine DNA Isolation Kit 

P-1017-100 100 Samples
EUR 292.6

ChromaFlash Chromatin Isolation & Shearing Kit 

P-2023-100 100 Preparations
EUR 189.2

XCF Exosomal DNA Isolation Kit

XCF200A-1 20 rxn
EUR 463.2

FitAmp Gel DNA Isolation Kit

P-1007 100 Samples
EUR 324.48

FitAmp Urine DNA Isolation Kit 

P-1017
  • EUR 474.12
  • EUR 171.60
  • EUR 292.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

ChromaFlash Chromatin Isolation & Shearing Kit 

P-2023
  • EUR 324.48
  • EUR 189.20
  • 100 Preperations
  • 100 Preparations

Total RNA Isolation Kit (Tissue)

P-9102 50 samples
EUR 416.7

Total RNA Isolation Kit (Plant)

P-9104 50 samples
EUR 416.7

EpiMag Viral RNA Isolation Kit

P-9108-050 50 samples
EUR 152.9

EVery EV RNA Isolation Kit

EVery100B-1 20 preps
EUR 412

ExoPure? Isolation Kit   (Cell Media)

K1237-10 each
EUR 796.8

ExoPure? Isolation Kit   (Cell Media)

K1237-2 each
EUR 470.4

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-10 each
EUR 836.4

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-2 each
EUR 470.4

ExoPure? Isolation Kit   (Bio Fluids)

K1241-10 each
EUR 836.4

ExoPure? Isolation Kit   (Bio Fluids)

K1241-2 each
EUR 483.6

Apoptotic DNA Ladder Isolation Kit

K170-50 each
EUR 561.6

EZExtract? Core Histone Isolation Kit

K234-100 each
EUR 314.4

Cell Surface Protein Isolation Kit

K295-10 each
EUR 601.2

Bacterial Genomic DNA Isolation Kit

K309-100 each
EUR 451.2

OrgFrontier? Plasma Membrane Isolation Kit

K414-10 each
EUR 679.2

Org Frontier? Chloroplast Isolation Kit

K468-10 each
EUR 666

Whole Blood DNA Isolation Kit

K528-100 each
EUR 451.2

CD19 Positive Cell Isolation Kit

78564-1 1 x 10^8 Cells
EUR 70
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal.

CD19 Positive Cell Isolation Kit

78564-2 1 x 10^9 Cells
EUR 630
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 319.2

PSEUDOMONAS ISOLATION AGAR

P16-114-10kg 10 kg
EUR 2058

PSEUDOMONAS ISOLATION AGAR

P16-114-2kg 2kg
EUR 494.4

PSEUDOMONAS ISOLATION AGAR

P16-114-500g 500 g
EUR 177.6

PSEUDOMONAS ISOLATION BROTH

P16-115-10kg 10 kg Ask for price

PSEUDOMONAS ISOLATION BROTH

P16-115-2Kg 2 Kg Ask for price

PSEUDOMONAS ISOLATION BROTH

P16-115-500g 500 g Ask for price

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1332

Pesticide Kit Containing All 10 Multi-Compound Mixes

SPXPR-KIT 1ML
EUR 1923.18

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS410A-KIT 1 kit (10 rxn)
EUR 798

Cas9-EGFP Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS420A-KIT 1 kit (10 rxn)
EUR 828

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1358.4

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1358.4

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1358.4

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1358.4

FastPure Bacteria DNA Isolation Mini Kit

DC103 100 rxn
EUR 212.4

FastPure Plant DNA Isolation Mini Kit

DC104 50 rxn
EUR 192

FastPure FFPE DNA Isolation Mini Kit

DC105 50 rxn
EUR 241.2

Rapid Bacteria Genomic DNA Isolation Kit

BS8225 50Preps
EUR 91.97

Soil DNA Isolation Mini Kit (50prep)

FASOI-001 50 preps
EUR 189.6

Soil DNA Isolation Mini Kit (100prep)

FASOI-001-1 100 preps
EUR 241.2

Soil DNA Isolation Midi Kit (24prep)

FASOI-002 24 preps
EUR 259.2

Soil RNA Isolation Mini Kit (50prep)

FASRK-001 50 preps
EUR 180

Soil RNA Isolation Mini Kit (100prep)

FASRK-100 100 preps
EUR 224.4

Mammalian Mitochondria Isolation Kit for Tissue

abx098857-50rxns 50 rxns
EUR 493.2

Rapid Fungal Genomic DNA Isolation Kit

FT71415 50Preps
EUR 91.97

Easy3-Plant Genomic DNA Isolation Kit

FYG503-100P 100 Preps Ask for price

Easy3-Plant Genomic DNA Isolation Kit

FYG503-500P 500 Preps Ask for price

Broad Range Total RNA Isolation Kit

K1341050 1 kit
EUR 319.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Blood and Serum DNA Isolation Kit

K5017100 1 kit
EUR 432

FitAmp Plasma/Serum DNA Isolation Kit 

P-1004-1 50 Samples
EUR 149.6

FitAmp Plasma/Serum DNA Isolation Kit 

P-1004-2 100 Samples
EUR 253

MagIso CD3 Cell Isolation Kit, Mouse

WHK-B009 20 tests, 200 tests Ask for price

MagIso CD90.2 Cell Isolation Kit, Mouse

WHK-B010 20 tests, 200 tests Ask for price

MagIso Neutrophil Cell Isolation Kit, Mouse

WHK-B015 10 tests, 100 tests Ask for price

MagIso CX3CR1 Cell Isolation Kit, Mouse

WHK-B017 10 tests, 100 tests Ask for price

MagIso NK Cell Isolation Kit, Human

WHK-B023 20 tests, 200 tests Ask for price

Methylamp Coupled DNA Isolation & Modification Kit

P-1002 40 Samples
EUR 474.12

FitAmp Plasma/Serum DNA Isolation Kit 

P-1004
  • EUR 416.70
  • EUR 149.60
  • EUR 253.00
  • 100 Samples
  • 50 Samples
  • 100 Samples

EpiQuik Total RNA Isolation Fast Kit

P-9105-050 50 samples
EUR 176

EpiQuik Magbeads Quick RNA Isolation Kit

P-9106-050 50 samples
EUR 163.9

EpiQuik Viral RNA Isolation Fast Kit

P-9107-050 50 samples
EUR 167.2

ExoPure? Isolation Kit   (Stem Cell Media)

K1239-10 each
EUR 901.2

ExoPure? Isolation Kit   (Stem Cell Media)

K1239-2 each
EUR 510

Plant Tissue Genomic DNA Isolation Kit

K316-100 each
EUR 451.2

Human Whole Blood Monocyte Isolation Kit

K933-30 each
EUR 451.2

Mammalian Cell Genomic DNA Isolation Kit

K967-100 each
EUR 457.2

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 966

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1358.4

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 183.6

Claritas PPT Grade Minerals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL

SPXMT-KIT 30ML
EUR 237.12

SanPrep Column microRNA Miniprep Kit

SK8811 50prep
EUR 151.32

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 5929.2

Claritas PPT Grade Heavy Metals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL

SPXHM-KIT 30ML
EUR 245.1

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 5929.2

cfMAX cfDNA Isolation System

CFMAX100A-1 1 Kit
EUR 574.8

Albumin, cold alcohol isolation

A0903 1g
EUR 99.67

RNA-easy Isolation Reagent

R701-01 100 ml
EUR 201.6

RNA-easy Isolation Reagent

R701-02 200 ml
EUR 254.4

Kinesis Rheodyne Isolation Seal

CHR2645 EACH
EUR 21.66

Kinesis Rheodyne Isolation Seal

CHR2791 EACH
EUR 37.62

10x Cell Isolation Buffer

78563 5 ml
EUR 25
Description: This buffer is intended for use with mammalian cells during magnetic cell isolation or single cell processing. This buffer is optimized and formulated to reduce nonspecific binding and cell clumping

FastPure Cell/Tissue DNA Isolation Mini Kit

DC102 100 rxn
EUR 212.4

FastPure Blood DNA Isolation Mini Kit V2

DC111-01 50 rxn
EUR 214.8

FastPure Blood DNA Isolation Mini Kit V2

DC111-02 200 rxn
EUR 472.8

One-Tube Bacteria Genomic DNA Isolation Kit

BS8413 100preps
EUR 94.72

One-Tube Bacteria Genomic DNA Isolation Kit

BS8414 500Preps, 500prep
EUR 198.85

Soil DNA Plus Isolation Mini Kit (50prep)

FAPSO-001 50 preps
EUR 189.6

Soil DNA Plus Isolation Mini Kit (100prep)

FAPSO-001-1 100 preps
EUR 241.2

Mammalian Mitochondria Isolation Kit for Cultured Cells

20-abx098856
  • EUR 126.00
  • EUR 493.20
  • 2 rxns
  • 50 rxns

FastPure Cell/Tissue Total RNA Isolation Kit

RC101 50 rxn
EUR 274.8

FitAmp General Tissue Section DNA Isolation Kit 

P-1003-1 50 Samples
EUR 253

FitAmp General Tissue Section DNA Isolation Kit 

P-1003-2 100 Samples
EUR 490.6

FitAmp Paraffin Tissue Section DNA Isolation Kit 

P-1009-1 50 Samples
EUR 239.8

FitAmp Paraffin Tissue Section DNA Isolation Kit 

P-1009-2 100 Samples
EUR 454.3

EpiQuik Circulating Cell-Free DNA Isolation Kit

P-1064-25 25 Isolations
EUR 148.5

EpiQuik Circulating Cell-Free DNA Isolation Kit

P-1064-50 50 Isolations
EUR 253

MagIso CD4 T Cell Isolation Kit, Human

WHK-B001 10 tests
EUR 724.8

MagIso CD8 T Cell Isolation Kit, Human

WHK-B002 10 tests
EUR 724.8

MagIso CD4 T Cell Isolation Kit, Mouse

WHK-B003 10 tests
EUR 724.8

MagIso CD8 T Cell Isolation Kit, Mouse

WHK-B004 10 tests
EUR 724.8

MagIso Hematopoietic Progenitor Cell Isolation Kit, Mouse

WHK-B005 10 tests
EUR 724.8

MagIso Hematopoietic Progenitor Cell Isolation Kit, Human

WHK-B008 20 tests, 200 tests Ask for price

MagIso Pan Dendritic Cell Isolation Kit, Mouse

WHK-B011 20 tests, 200 tests Ask for price

MagIso Pan B Cell Isolation Kit, Mouse

WHK-B013 20 tests, 200 tests Ask for price

MagIso Hematopoietic Progenitor Cell Isolation Kit, Mouse

WHK-B016 10 tests, 100 tests Ask for price

MagIso Pan Monocyte Cell Isolation Kit, Human

WHK-B021 20 tests, 200 tests Ask for price

MagIso Pan B Cell Isolation Kit, Human

WHK-B022 20 tests, 200 tests Ask for price

MagIso Naïve B Cell Isolation Kit, Human

WHK-B024 20 tests, 200 tests Ask for price

MagIso CD14+ Monocytes Cell Isolation Kit, Human

WHK-B029 10 tests, 100 tests Ask for price

FitAmp General Tissue Section DNA Isolation Kit 

P-1003
  • EUR 754.26
  • EUR 253.00
  • EUR 490.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

FitAmp Paraffin Tissue Section DNA Isolation Kit 

P-1009
  • EUR 702.06
  • EUR 239.80
  • EUR 454.30
  • 100 Samples
  • 50 Samples
  • 100 Samples

EpiMag High Throughput DNA Isolation Universal Kit

P-1022-96 96 Samples
EUR 227.7

EpiQuik Circulating Cell-Free DNA Isolation Kit

P-1064
  • EUR 416.70
  • EUR 148.50
  • EUR 253.00
  • 50 Isolations
  • 25 Isolations
  • 50 Isolations

Human Whole Blood Polymorphonuclear Cell Isolation Kit

K483-30 each
EUR 451.2

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE620A-KIT 1 kit
EUR 2558.4

AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE622A-KIT 1 kit
EUR 2558.4

AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE624A-KIT 1 kit
EUR 2558.4

vWF Acty. Kit

ABP-ACT-KIT 12 x 8 microwells
EUR 513.6

vWF Ant. Kit

ABP-TOT-KIT 12 x 8 microwells
EUR 472.8

hsa-miRNome MicroRNA Profiling Kit [Human]

RA660A-1 20 profiles
EUR 2212.8

mmu-miRNome MicroRNA Profiling Kit [Mouse]

RA670A-1 20 profiles
EUR 2046

rno-miRNome MicroRNA Profiling Kit [Rat]

RA680B-1 20 complete profiles
EUR 2006.4

SmartSEC Single EV Isolation System

SSEC200A-1 10 rxn
EUR 391

Cell Isolation Magnetic Tube Rack

78571 15 ml and 50 ml
EUR 850
Description: This Cell Isolation Magnetic Tube Rack is designed to accompany our magnetic cell isolation products, such as the CD19 Positive Cell Isolation Kit (BPS Bioscience #78564). This magnet can quickly separate cells labeled with magnetic beads and is designed to allow users a near 360° view of their cell samples during separation. This magnet can accommodate both 15 and 50 ml tubes simultaneously, which allows flexibility for scaling up or down your isolation samples. Additionally, the rack is compatible with both conical and round-bottom tubes. The compact nature of this magnet allows it to fit easily in various incubators or refrigerators to match desired conditions.

PrecisionX Multiplex gRNA Cloning Kit

CAS9-GRNA-KIT 10 rxn
EUR 534

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps)

CBA-155 5 preps
EUR 957.6
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

Mitochondria Isolation Kit for Tissue and Cultured Cells

KC010100 1 kit
EUR 384
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

MagIso Pan B Cell Isolation Kit, Mouse Ⅱ

WHK-B012 20 tests, 200 tests Ask for price

MagIso Natural killer (NK) Cell Isolation Kit, Mouse

WHK-B014 20 tests, 200 tests Ask for price

MagIso CD8 Naïve T Cell Isolation Kit, Mouse

WHK-B018 20 tests, 200 tests Ask for price

MagIso CD4 Naïve T Cell Isolation Kit, Mouse

WHK-B019 20 tests, 200 tests Ask for price

MagIso CD8 Naïve T Cell Isolation Kit, Human

WHK-B025 20 tests, 200 tests Ask for price

MagIso CD8 Memory T Cell Isolation Kit, Human

WHK-B026 20 tests, 200 tests Ask for price

MagIso CD4 Naïve T Cell Isolation Kit, Human

WHK-B027 20 tests, 200 tests Ask for price

MagIso CD4 Memory T Cell Isolation Kit, Human

WHK-B028 20 tests, 200 tests Ask for price


The diagnosis of obstructive sleep apnea (OSA) in Alzheimer’s disease (AD) by polysomnography (PSG) challenging because of the collaboration required of the patient. In addition, screening questionnaires have shown limited usefulness in this subpopulation. Considering this, we investigated circulating microRNA (miRNA) profiles associated with OSA in patients with AD. This study included a carefully selected group of females with mild-moderate AD is confirmed by biological evaluation (n = 29). Individuals submitted to one night PSG to diagnose (apnea-hypopnea index ≥ 15 / h) OSA and the blood collected in the next morning.