Treatment with Tang-luo-ning altered the microRNA expression profile in rats with diabetic peripheral neuropathy

Tang-luo-ning (TLN) is a traditional Chinese herbal recipe that has been used to treat diabetic peripheral neuropathy (DPN); However, the underlying mechanisms are still unclear. This study aims to investigate microRNA (miRNA) expression profiles in diabetic rats treated with TLN, and the predicted target genes. Male Sprague-Dawley rats were randomly divided into control, diabetes, and TLN-treated diabetic groups. Diabetes was induced with streptozotocin, and TLN (5 g / kg / day) orally administered for eight weeks.

Then, the sciatic nerve is harvested for miRNA microarray analysis. The differentially expressed miRNAs and their target genes analyzed. Compared with control mice, 24 miRNAs were significantly upregulated and 59 were downregulated in the sciatic nerves of diabetic mice with more than two-fold (all P <0.05). On TLN-treated diabetic mice, 26 miRNAs were upregulated and 14 downregulated compared with diabetic mice without treatment TLN (all P <0.05). DPN-induced changes of miRNA profiles TLN reversed with treatment.

A total of 1,402 of the target genes screened. In the GO analysis, gene localization, cytoplasm, and the enriched protein binding, and the most significantly enriched including neurotrophin, Fc epsilon RI, and the Wnt signaling pathway. Further analysis revealed that DVL1 and NTF3 genes involved in this pathway. Our findings suggest that TLN can affect Wnt and neurotrophin pathway by acting on the genes DVL1 and NTF3.

 Treatment with Tang-luo-ning altered the microRNA expression profile in rats with diabetic peripheral neuropathy
Treatment with Tang-luo-ning altered the microRNA expression profile in rats with diabetic peripheral neuropathy

Find signatures of lupus-related microRNA profile in the Gene Expression Omnibus repository

Lupus is one of the most common autoimmune disease systemic. It is a multifactorial disease that is genetic, epigenetic and environment plays a significant role. The pathogenesis of lupus is not well understood. However, deregulation of microRNAs (miRNAs) – one of the post-transcriptional regulators of gene – may contribute to the development of autoimmune disease.

Over the past two decades, advances in miRNA profiling using microarray has received a lot of attention, and it has been demonstrated that miRNAs play a regulatory role in the pathogenesis of lupus. Therefore, dysregulated miRNAs can be considered as a promising diagnostic biomarker for lupus. This article is an overview of lupus-related miRNA array profiles and studies in the Gene Expression Omnibus (GEO) database. The aim of our research is to expand the current knowledge dysregulated miRNAs known as a potential biomarker of SLE and to introduce a bioinformatics approach to using microarray data and find novel miRNA and gene candidates for further study. We identified HSA-miR-4709-5p, HSA-mir-140, mir-145-HSA, HSA-mir-659, mir-134-HSA, HSA-mir-150, mir-584-HSA, HSA-Mirza HSA-409 and miR-152 as a potential biomarker with integrated bioinformatics analysis.

miRNA Isolation Kit

FAMIK--002 Rxns: 50
EUR 223

miRNA Isolation Kit

FYG304-100P 100 Preps Ask for price

Microsome Isolation Kit

K249-50
EUR 528

Preadipocyte Isolation Kit

K583-5
EUR 533

Endosome Isolation Kit

P528 NULL
EUR 0

Easy3-RNA Isolation Kit

FYG501-100P 100 Preps Ask for price

Easy3-RNA Isolation Kit

FYG501-500P 500 Preps Ask for price

Cell Mitochondria Isolation Kit

abx090630-50100tests 50-100 tests
EUR 258
  • Shipped within 5-10 working days.

Tissue Mitochondria Isolation Kit

abx090631-50100assays 50-100 assays
EUR 258
  • Shipped within 5-10 working days.

Apoptotic Cell Isolation Kit

55R-1349 30 units
EUR 729
Description: Apoptotic Cell Isolation Kit for use in the research laboratory

Mitochondrial DNA Isolation Kit

55R-1361 50 assays
EUR 825
Description: Mitochondrial DNA Isolation Kit for use in the research laboratory

Genomic DNA Isolation Kit

55R-1362 50 assays
EUR 385
Description: Genomic DNA Isolation Kit for use in the research laboratory

ExoPure? Isolation Kit   (Urine)

K1240-10
EUR 697

ExoPure? Isolation Kit   (Urine)

K1240-2
EUR 403

Cartilage RNA Isolation Kit

K2031010 1 kit
EUR 419
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Mitochondrial DNA Isolation Kit

K2117-50 50 assays
EUR 599

Genomic DNA Isolation Kit

K2118-50 50 assays
EUR 321

Mitochondrial DNA Isolation Kit

K280-50
EUR 588

Genomic DNA Isolation Kit

K281-50
EUR 272

Apoptotic Cell Isolation Kit

K258-30
EUR 468

Yeast Nuclei Isolation Kit

K289-50
EUR 392

Yeast Mitochondria Isolation Kit

K259-50
EUR 419

Lipopolysaccharide (LPS) Isolation Kit

K438-10
EUR 278

Serum DNA Isolation Kit

K5018100 1 kit
EUR 360

Saliva DNA Isolation Kit

K5011050 1 kit
EUR 256

Urine DNA Isolation Kit

K5011150 1 kit
EUR 256

Stool DNA Isolation Kit

K5011250 1 kit
EUR 256

Lipid Droplet Isolation Kit

MET-5011 50 preps
EUR 415
Description: Lipid droplets are lipid rich organelles found in the adipose tissue of eukaryotes. They function to regulate the hydrolysis and storage of neutral lipids and serve as storage for cholesterol and acyl-glycerols. Lipid droplets have also been associated with inflammatory responses, obesity, atherosclerosis, and cancer.

Total RNA Isolation Kit

P-9100 50 samples
EUR 347.25
Description: The best epigenetics products

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Circulating Nuleic Acid Isolation Kit

FACFK-050 50 preps
EUR 491

Circulating Nuleic Acid Isolation Kit

FACFK-100 100 preps
EUR 825

Total RNA Isolation Kit II

FATRS--001 100 preps
EUR 308

Total RNA Isolation Kit II

FATRS--050 50 preps
EUR 216

Easy3-Plant RNA Isolation Kit

FYG502-100P 100 Preps Ask for price

Easy3-Plant RNA Isolation Kit

FYG502-500P 500 Preps Ask for price

Easy3-Total NucleicAcid Isolation Kit

FYG504-100ML 100 ml Ask for price

Easy3-Total NucleicAcid Isolation Kit

FYG504-500ML 500 ml Ask for price

Exo-Urine EV Isolation Kit

EXOU100A-1 2 x 5 reactions
EUR 551

ExoPure? Isolation Kit   (Cell Media)

K1237-10
EUR 664

ExoPure? Isolation Kit   (Cell Media)

K1237-2
EUR 392

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-10
EUR 697

ExoPure? Isolation Kit   (Serum, Plasma)

K1238-2
EUR 392

ExoPure? Isolation Kit   (Bio Fluids)

K1241-10
EUR 697

ExoPure? Isolation Kit   (Bio Fluids)

K1241-2
EUR 403

Apoptotic DNA Ladder Isolation Kit

K170-50
EUR 468

Apoptotic DNA Ladder Isolation Kit

K2045-50 50 assays
EUR 502

EZExtract? Core Histone Isolation Kit

K234-100
EUR 262

Cell Surface Protein Isolation Kit

K295-10
EUR 501

Org Frontier? Chloroplast Isolation Kit

K468-10
EUR 555

OrgFrontier? Plasma Membrane Isolation Kit

K414-10
EUR 566

Bacterial Genomic DNA Isolation Kit

K309-100
EUR 376

Whole Blood DNA Isolation Kit

K528-100
EUR 376

Exosome Isolation kit (for urine)

P120L NULL
EUR 0

Exosome Isolation kit (for urine)

P120S NULL
EUR 0

FitAmp Gel DNA Isolation Kit

P-1007 100 Samples
EUR 270.4
Description: The best epigenetics products

FitAmp Urine DNA Isolation Kit

P-1017 100 Samples
EUR 395.1
Description: kits suitable for this type of research

ChromaFlash Chromatin Isolation & Shearing Kit

P-2023 100 Preperations
EUR 270.4
Description: kits suitable for this type of research

Total RNA Isolation Kit (Tissue)

P-9102 50 samples
EUR 347.25
Description: reagents widely cited

Total RNA Isolation Kit (Plant)

P-9104 50 samples
EUR 347.25
Description: kits suitable for this type of research

Detergent-Free Nuclei Isolation Kit

P524-2 NULL
EUR 0

Detergent-Free Nuclei Isolation Kit

P524-20 NULL
EUR 0

Detergent-Free Nuclei Isolation Kit

P524-80 NULL
EUR 0

Lysosome Isolation Kit (20 tests)

P534 NULL
EUR 0

Mouse Brain Microvessel Isolation Kit

P750-4 NULL
EUR 0

XCF Exosomal DNA Isolation Kit

XCF200A-1 20 rxn
EUR 386
  • Category: Exosome

Rapid Plant RNA Isolation Kit

PT4191 50Preps
EUR 79.69
  • Product category: Molecular Biology Kits/RNA - Extraction/Plant

Rapid Bacteria RNA Isolation Kit

BS8625 50Preps
EUR 79.69
  • Product category: Molecular Biology Kits/RNA - Extraction/Bacteria

Rapid Blood RNA Isolation Kit

BT4182 10Preps
EUR 81.97
  • Product category: Molecular Biology Kits/RNA - Extraction/Blood

Rapid Blood RNA Isolation Kit

BT4183 50Preps
EUR 164.19
  • Product category: Molecular Biology Kits/RNA - Extraction/Blood

Rapid Blood RNA Isolation Kit

BT4184 250preps
EUR 506.75
  • Product category: Molecular Biology Kits/RNA - Extraction/Blood

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PSEUDOMONAS ISOLATION AGAR

P16-114-10kg 10 kg
EUR 1715

PSEUDOMONAS ISOLATION AGAR

P16-114-2kg 2kg
EUR 412

PSEUDOMONAS ISOLATION AGAR

P16-114-500g 500 g
EUR 148

PSEUDOMONAS ISOLATION BROTH

P16-115-10kg 10 kg Ask for price

PSEUDOMONAS ISOLATION BROTH

P16-115-2Kg 2 Kg Ask for price

PSEUDOMONAS ISOLATION BROTH

P16-115-500g 500 g Ask for price

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

Soil DNA Isolation Mini Kit (50prep)

FASOI-001 50 preps
EUR 158

Soil DNA Isolation Mini Kit (100prep)

FASOI-001-1 100 preps
EUR 201

Soil DNA Isolation Midi Kit (24prep)

FASOI-002 24 preps
EUR 216

Soil RNA Isolation Mini Kit (50prep)

FASRK-001 50 preps
EUR 150

Soil RNA Isolation Mini Kit (100prep)

FASRK-100 100 preps
EUR 187

Easy3-Plant Genomic DNA Isolation Kit

FYG503-100P 100 Preps Ask for price

Easy3-Plant Genomic DNA Isolation Kit

FYG503-500P 500 Preps Ask for price

Mammalian Mitochondria Isolation Kit for Tissue

abx098857-50rxns 50 rxns
EUR 411
  • Shipped within 5-10 working days.

ExoPure? Isolation Kit   (Stem Cell Media)

K1239-10
EUR 751

ExoPure? Isolation Kit   (Stem Cell Media)

K1239-2
EUR 425

FastPure Bacteria DNA Isolation Mini Kit

DC103 100 rxn
EUR 177

FastPure Plant DNA Isolation Mini Kit

DC104 50 rxn
EUR 160

FastPure FFPE DNA Isolation Mini Kit

DC105 50 rxn
EUR 201

Broad Range Total RNA Isolation Kit

K1341050 1 kit
EUR 266
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Plant Tissue Genomic DNA Isolation Kit

K316-100
EUR 376

Blood and Serum DNA Isolation Kit

K5017100 1 kit
EUR 360

Human Whole Blood Monocyte Isolation Kit

K933-30
EUR 376

Mammalian Cell Genomic DNA Isolation Kit

K967-100
EUR 381

Exosome Isolation kit (for serum & plasma)

P101 NULL
EUR 0

Exosome Isolation kit (for serum & plasma)

P101L NULL
EUR 0

Exosome Isolation kit (for serum & plasma)

P101S NULL
EUR 0

Exosome Isolation kit (forHuman Body Fluid)

P121 NULL
EUR 0

Exosome Isolation kit (forHuman Body Fluid)

P121L NULL
EUR 0

Exosome Isolation kit (forHuman Body Fluid)

P121S NULL
EUR 0

Methylamp Coupled DNA Isolation & Modification Kit

P-1002 40 Samples
EUR 395.1
Description: The best epigenetics products

FitAmp Plasma/Serum DNA Isolation Kit

P-1004 100 Samples
EUR 347.25
Description: fast delivery possible

Mitochondria Isolation Kit (Mammalian cells / tissues)

P507L NULL
EUR 0

10-min. Single Cell Isolation Kit

P713-20 NULL
EUR 0

MagIso CD3 Cell Isolation Kit, Mouse

WHK-B009 20 tests, 200 tests Ask for price

MagIso CD90.2 Cell Isolation Kit, Mouse

WHK-B010 20 tests, 200 tests Ask for price

MagIso Neutrophil Cell Isolation Kit, Mouse

WHK-B015 10 tests, 100 tests Ask for price

MagIso CX3CR1 Cell Isolation Kit, Mouse

WHK-B017 10 tests, 100 tests Ask for price

MagIso NK Cell Isolation Kit, Human

WHK-B023 20 tests, 200 tests Ask for price

Rapid Fungal Genomic DNA Isolation Kit

FT71415 50Preps
EUR 76.64
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Fungi

Rapid Bacteria Genomic DNA Isolation Kit

BS8225 50Preps
EUR 76.64
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Bacteria

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

cfMAX cfDNA Isolation System

CFMAX100A-1 1 Kit
EUR 479
  • Category: Liquid Biopsy

RNA-easy Isolation Reagent

R701-01 100 ml
EUR 168

RNA-easy Isolation Reagent

R701-02 200 ml
EUR 212

Albumin, cold alcohol isolation

A0903 1g
EUR 83.06
  • Product category: Proteins/Albumin

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153
  • Category: Cas9

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 4941
  • Category: PinPoint Integrase Tools

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 4941
  • Category: PinPoint Integrase Tools

Soil DNA Plus Isolation Mini Kit (50prep)

FAPSO-001 50 preps
EUR 158

Soil DNA Plus Isolation Mini Kit (100prep)

FAPSO-001-1 100 preps
EUR 201

Mammalian Mitochondria Isolation Kit for Cultured Cells

20-abx098856
  • EUR 105.00
  • EUR 411.00
  • 2 rxns
  • 50 rxns
  • Shipped within 5-10 working days.

FastPure Cell/Tissue DNA Isolation Mini Kit

DC102 100 rxn
EUR 177

FastPure Blood DNA Isolation Mini Kit V2

DC111-01 50 rxn
EUR 179

FastPure Blood DNA Isolation Mini Kit V2

DC111-02 200 rxn
EUR 394

Human Whole Blood Polymorphonuclear Cell Isolation Kit

K483-30
EUR 376

Exosome Isolation kit (for cell culture media)

P100 NULL
EUR 0

Exosome Isolation kit (for cell culture media)

P100L NULL
EUR 0

Exosome Isolation kit (for cell culture media)

P100S NULL
EUR 0

FitAmp General Tissue Section DNA Isolation Kit

P-1003 100 Samples
EUR 628.55
Description: kits suitable for this type of research

FitAmp Paraffin Tissue Section DNA Isolation Kit

P-1009 100 Samples
EUR 585.05
Description: Ask the seller for details

EpiQuik Circulating Cell-Free DNA Isolation Kit

P-1064 50 Isolations
EUR 347.25
Description: kits suitable for this type of research

8-min Intact Plant Chloroplast Isolation Kit

P511L NULL
EUR 0

Tissue (Tumor) Dissociation / Single Cell Isolation Kit

P712-25 NULL
EUR 0

Tissue (Tumor) Dissociation / Single Cell Isolation Kit

P712-4 NULL
EUR 0

Tissue (Tumor) Dissociation / Single Cell Isolation Kit

P712-50 NULL
EUR 0

FastPure Cell/Tissue Total RNA Isolation Kit

RC101 50 rxn
EUR 229

MagIso CD4 T Cell Isolation Kit, Human

WHK-B001 10 tests
EUR 604

MagIso CD8 T Cell Isolation Kit, Human

WHK-B002 10 tests
EUR 604

MagIso CD4 T Cell Isolation Kit, Mouse

WHK-B003 10 tests
EUR 604

MagIso CD8 T Cell Isolation Kit, Mouse

WHK-B004 10 tests
EUR 604

MagIso Hematopoietic Progenitor Cell Isolation Kit, Mouse

WHK-B005 10 tests
EUR 604

MagIso Hematopoietic Progenitor Cell Isolation Kit, Human

WHK-B008 20 tests, 200 tests Ask for price

MagIso Pan Dendritic Cell Isolation Kit, Mouse

WHK-B011 20 tests, 200 tests Ask for price

MagIso Pan B Cell Isolation Kit, Mouse

WHK-B013 20 tests, 200 tests Ask for price

MagIso Hematopoietic Progenitor Cell Isolation Kit, Mouse

WHK-B016 10 tests, 100 tests Ask for price

MagIso Pan Monocyte Cell Isolation Kit, Human

WHK-B021 20 tests, 200 tests Ask for price

MagIso Pan B Cell Isolation Kit, Human

WHK-B022 20 tests, 200 tests Ask for price

MagIso Naïve B Cell Isolation Kit, Human

WHK-B024 20 tests, 200 tests Ask for price

MagIso CD14+ Monocytes Cell Isolation Kit, Human

WHK-B029 10 tests, 100 tests Ask for price

One-Tube Bacteria Genomic DNA Isolation Kit

BS8413 100preps
EUR 78.93
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Bacteria

One-Tube Bacteria Genomic DNA Isolation Kit

BS8414 500Preps, 500prep
EUR 165.71
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Bacteria

SanPrep Column microRNA Miniprep Kit

SK8811 50prep
EUR 126.1
  • Product category: Molecular Biology Kits/RNA - microRNA Extraction/Multipurpose

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE620A-KIT 1 kit
EUR 2132
  • Category: Gene Editing

AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE622A-KIT 1 kit
EUR 2132
  • Category: Gene Editing

AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE624A-KIT 1 kit
EUR 2132
  • Category: Gene Editing

vWF Acty. Kit

ABP-ACT-KIT 12 x 8 microwells
EUR 428

vWF Ant. Kit

ABP-TOT-KIT 12 x 8 microwells
EUR 394

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps)

CBA-155 5 preps
EUR 798
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

Mammalian Mitochondria Isolation Kit For Tissue & Cultured Cells

K288-50
EUR 419

Mitochondria Isolation Kit for Tissue and Cultured Cells

KC010100 1 kit
EUR 320
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Exosome Isolation kit (for stem cell culture media)

P107 NULL
EUR 0

Exosome Isolation kit (for stem cell culture media)

P107S NULL
EUR 0

Nuclei and Cytosol Isolation Kit for Adipose Tissues

P529 NULL
EUR 0

Easy-Exo Saliva Exosome Isolation Kit, 95% pure

P530 NULL
EUR 0

Easy-Exo Saliva Exosome Isolation Kit, 95% pure

P530S NULL
EUR 0

Hipro Circulating Cell-Free DNA (cfDNA) Isolation Kit

W2603-10 NULL
EUR 0

Hipro Circulating Cell-Free DNA (cfDNA) Isolation Kit

W2603-20 NULL
EUR 0

Hipro Circulating Cell-Free DNA (cfDNA) Isolation Kit

W2603-50 NULL
EUR 0

MagIso Pan B Cell Isolation Kit, Mouse Ⅱ

WHK-B012 20 tests, 200 tests Ask for price

MagIso Natural killer (NK) Cell Isolation Kit, Mouse

WHK-B014 20 tests, 200 tests Ask for price

MagIso CD8 Naïve T Cell Isolation Kit, Mouse

WHK-B018 20 tests, 200 tests Ask for price

MagIso CD4 Naïve T Cell Isolation Kit, Mouse

WHK-B019 20 tests, 200 tests Ask for price

MagIso CD8 Naïve T Cell Isolation Kit, Human

WHK-B025 20 tests, 200 tests Ask for price

MagIso CD8 Memory T Cell Isolation Kit, Human

WHK-B026 20 tests, 200 tests Ask for price

MagIso CD4 Naïve T Cell Isolation Kit, Human

WHK-B027 20 tests, 200 tests Ask for price

MagIso CD4 Memory T Cell Isolation Kit, Human

WHK-B028 20 tests, 200 tests Ask for price


The diagnosis of obstructive sleep apnea (OSA) in Alzheimer’s disease (AD) by polysomnography (PSG) challenging because of the collaboration required of the patient. In addition, screening questionnaires have shown limited usefulness in this subpopulation. Considering this, we investigated circulating microRNA (miRNA) profiles associated with OSA in patients with AD. This study included a carefully selected group of females with mild-moderate AD is confirmed by biological evaluation (n = 29). Individuals submitted to one night PSG to diagnose (apnea-hypopnea index ≥ 15 / h) OSA and the blood collected in the next morning.